Abstract:This proposed project is to develop a novel class of high-temperature, high-energy-product permanent magnets with minimized rare-earth element based on a two-phase (Sm2Fe17N3)1-x(Co35Fe65)x (0<x<0.8). The resultant two-phase magnetic materials, which can be fabricated by a cost-effective,… more
Abstract:Project Summary / Abstract - EY020017 Phase IIB Competitive Renewal The overall goal of the proposed SBIR program is to implement and evaluate a low cost, portable retinal camera, the DLP-Cam, in a primary care system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels… more
Abstract:A microphone array system for studying the near field hydrodynamic region adjacent to the supersonic exhaust plume of a tactical aircraft engine in a ground test fixture at approximately 20 feet above the ground. It will consist of approximately 160 microphones aimed radially inward at the edge of… more
Abstract:ABSTRACT: Aerobotix personnel have engineered and delivered eight turn-key robotic painting systems to apply performance coatings to the inlet ducts of several major programs. These successful systems are comprised of off-the-shelf FANUC robots outfitted with long composite tools to reach inside… more
Abstract:End Cryptographic Units (ECUs) and associated security module, are essential for protecting satellite communications that include payload data, control commands, status, and bent-pipe operations. Legacy systems such as require cryptographic needs for Communication security (COMSEC) and Transmission… more
Abstract:Water heaters use about 16% of the energy used in the typical home. This is an unnecessary financial burden on most home owners and an unnecessary burden on US energy supplies. Currently, the high cost of solar hot water systems discourages alternatives to Natural gas, Propane and electric water… more
Abstract:A significant challenge in scaling micro-propulsion devices up to 100s of Watts as well as scaling macro devices down to sub-kiloWatt level is the lack of a compatible neutralizer technology in the meso scale. Sub-kiloWatt EP systems require cathode technology that can produce sufficient current… more
Abstract:AeroSoft, with the USAFA Laser and Optics Research Center proposes to create an extensive and thorough Verification and Validation (V & V) Program for anchoring physics based modeling software for static and flowing DPAL systems. During Phase I, a review of existing experimental programs will… more
Abstract:Atmospheric nucleation processes produce large numbers of particles. Once formed, these particles grow rapidly and may alter the formation and lifetime of clouds, and thereby influence the earths radiation balance. Rapid growth of newly formed particles has been observed in many locations, but it is… more
Abstract:ABSTRACT: Proposed is a miniature sensor for real time measurement of nano-particle number concentration, surface area and size distributions, and for time- and size-resolved collection of these particles for off-line analysis. This instrument combines two novel technologies: (1) a self-sustaining… more
Abstract:DESCRIPTION (provided by applicant): Cell culture studies allow air pollution researchers to assess toxicological outcomes that can be later used in human exposure models and risk assessment studies. However, there are only a few collection systems that allow direct cellular exposure to ambient… more
Abstract:ABSTRACT Size-Resolved Measurement of Ultrafine and Nanometer Particle Concentrations This proposal addresses the need to assess worker and community exposure to engineered nanomaterials and other ultrafine particles. The ultimate aim is the development ofa compact, battery powered instrument for… more
Abstract:Every asset ages. Pipes, roads, computers, cars, etc. This fact is inevitable. And, as a result of the aging process, every asset suffers a degradation in its intended capability or performance over time. Yet every day, millions of people in the U.S. get up in the morning expecting that they will be… more
Abstract:The objective of this SBIR project is to develop the technologies needed to allow innovative, high performance avionics systems, subsystems, and components that will enhance the capability of successfully achieving early intercept missile defense in current and future interceptors in all hostile… more
Abstract:DESCRIPTION (provided by applicant): Sleep deprivation (SD) occurs universally in modern societies and causes significant social and financial harm. Numerous human and animal studies indicate that various forms of SD are deleterious to mental and physicalhealth. Therefore, SD has been recognized as… more
Abstract:DESCRIPTION (provided by applicant): Development of Novel Tricyclic Pyrone Drugs for Treatment of Alzheimer's Disease Alzheimer's disease (AD) afflicts approximately 35 million people worldwide and is the most common cause of dementia in the elderly. Thereis an unmet medical need for new… more
Abstract:DESCRIPTION (provided by applicant): Our completed SBIR Phase I project (R43 DA031578) was in response to NIH PA11-096, PHS 2011-02 'Omnibus solicitation for SBIR/STTR Grant Application' under NIDA 2, Development of Alternate Drug Delivery Dosage Forms for Drugs Abuse Studies. We have… more
Abstract:Under this Small Business Innovation Research (SBIR) Phase I project, Research Topic 149, the Contractor shall develop predictive in vivo screening systems for phenotypic drug discovery for smoking cessation. The Contractor shall accomplish this throughthe following objectives: Objective 1-… more
Abstract:Vesitech, Inc. has developed a totally new class of water treatment technology utilizing novel carbon based electrodes that have been shown to electrochemically produce advanced oxidation (AO) species in-situ in contaminated water. Depending upon the electrode formulation and configuration, the… more
Abstract:The chloroperoxidase enzyme from the filamentous fungus Caldariomyces fumago has applications in industrial chemical synthesis and the detection and inactivation of chemical warfare agents. Chloroperoxidase is capable of regio- and enantioselective oxygenations and halogenations of organic… more
Abstract:Bacterial enteric pathogens causing travelers"diarrhea (TD) in developing countries include enterotoxigenic E. coli (50%), Camplyobacter jejuni, Shigella sonnei and Shigella flexneri, while Norovirus is a common viral cause. High risk regions for TD include areas where US service members are… more
Abstract:Agave BioSystems, with their academic partners at the Mote Marine Laboratory, proposes to develop probiotic pharmaceuticals from indigenous commensal microbes to enhance gastrointestinal health in the bottlenose dolphin (Tursiops truncatus). The dolphin gastrointestinal microbiome will be… more
Abstract:Wound management becomes increasingly challenging due to bacterial infections, especially from epidemic drug-resistant strains. To address this problem, Agave BioSystems proposes to develop a RANT (Rapidly Adaptable Nanotherapeutics) breadboard system built upon the modules successfully established… more
Abstract:Agiltron Inc. proposes to develop a compact, sensitive, and selective tunable diode laser absorption spectroscopy (TDLAS) based multi-gas sensor for OBOGS breathing oxygen monitoring. In the proposed research, novel laser diodes that output wavelength tunable from 2000 nm to 3500 nm will be used to… more
Abstract:ABSTRACT: In this program, Agiltron, Inc. and Harvard University will develop a biologically-inspired integrated sensor that can detect the UV, visible (VIS), near infrared (NIR), and mid-wave infrared (MWIR) bands. This sensor will be integrated with plasmonic filters to provide additional… more
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