Abstract:Folic acid is a water-soluble vitamin that serves as a cofactor in 1-carbon transfers required for DNA replication. Humans lack the enzymes to synthesize folate, so dietary intake is necessary. Its deficiency is associated with neural tube defects (NTDs) in fetuses. The global burden of folate… more
Abstract:Breast, cervical, and colorectal cancer can be successfully prevented and/or diagnosed and successfully treated at the earliest stages through use of appropriate and timely screening and adequate follow-up and care coordination. Recognizing the importance of cancer screening, groups like the… more
Abstract:A rapid respond to outbreaks critically depends on laboratory confirmation of suspected measles cases. In general, the turnaround times for serologic test results provided by the WHO Measles/Rubella Laboratory Network are adequate; however, results from specimens collected in remote areas can be… more
Abstract:We propose to design a compact, high-precision, single-axis accelerometer based on atom interferometry that is applicable to operation in space environments. Our design will emphasize reliable operation and minimization of the acceleration noise floor, bias drifts and scale factor instability. Laser… more
Abstract:AOSense has successfully designed and fabricated numerous laser systems for applications ranging from a rubidium Bose-Einstein condensate (BEC) apparatus to ultracold cesium and rubidium atom trapping. This SBIR topic is well-matched to our experience in designing integrated, rugged laser systems… more
Abstract:AOSense proposes an atom interferometer based inertial measurement unit that is capable of meeting the navigational requirements of surface ships and submarines. Real-world applications require extensive optimization of various interferometer design choices in order to deal with platform dynamics.… more
Abstract:AOSense has successfully designed and fabricated numerous cold-atom-based sensors, including lasers, vacuum systems, optomechanics and control electronics. This SBIR topic is well-matched to our experience in developing systems for the manipulation of ultracold atoms. We propose to design and… more
Abstract:We propose to leverage the expertise of Applied Nanotech, Inc. (ANI) in building highly sensitive, selective, portable and versatile GC/DMS instruments, to create a system to uniquely identify a pollen species based on its VOC profile. This project will determine which VOCs shall be collected and… more
Abstract:Applied Nanotech Inc. (ANI) proposes to continue application development of its proprietary thermal management composite, (CarbAl(TM)). CarbAl(TM) is a carbon-aluminum composite with low coefficient of thermal expansion (CTE), high thermal conductivity, low density and low cost. The Phase I… more
Abstract:Uniquely identifying an individual based on biometric information can currently be performed by using fingerprints, facial images and eye scans. These techniques frequently require the cooperation or at a minimum the acknowledgement from an individual that information is being gathered from them. … more
Abstract:The research objective of the proposed work is to apply the foundational knowledge of ultrasonic bonding, metallic composites, microstructure transformation kinetics and material failure criteria to create a multi-scale simulation model for the optimization of ultrasonic additive manufacturing (UAM)… more
Abstract:ABSTRACT: Applied Optimization, Inc. (AO) has developed computational process simulation for the prediction of temperature, residual stress, and melt pool control during the material feed DDM processes (e.g. LENSTM and EBFFF). The Phase I work plan is to extend this existing simulation technology… more
Abstract:ABSTRACT: Applied Optimization, Inc. proposes to develop a prototype hardware and software system for concurrent collection of metric observations and single-point spectral brightness data. The concurrency will be attained by using all but a few percent of the CCD pixel array for metric… more
Abstract:The first objective of this Phase II is to develop and demonstrate thermally controlled direct digital manufacturing (DDM) of Ti-6Al-4V that will have the ability to produce uniform/desired microstructure in a repeatable manner. The proposed method will be designed to provide a quasi steady and… more
Abstract:ABSTRACT: All High Energy Laser (HEL) systems require accurate pointing and precise stabilization of the laser beam to be effective. HEL systems hosted on aircraft pose an additional challenge to beam stabilization efforts due to the harsh linear and angular vibration environments inherent in such… more
Abstract:ATA proposes to develop, test and deliver an Optical Inertial Reference Unit (OIRU) called the MSTAR Inertial Reference Unit with DRGs (MIRU-D). The MIRU-D will incorporate four ATA ARS-14s and four Boeing MEMS DRGs on the inertially stable side of the MIRU-D. The efforts in Phase II will lay the… more
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