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Year:2012
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Displaying 5526 – 5550 of 5641 Awards
Company: 23ANDME, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Genetics of Allergic Disease in a Participatory Research Cohort Asthma and allergic disease are extremely common conditions with substantial public health burdens, affecting as many as one in five Americans. Discovery of genetic variants affecting allergic… more
Company: CYLERUS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The Company's business and research efforts are focused on developing and commercializing a novel drug delivery approach to prevent the abnormal ingrowth of tissue (intimal hyperplasia) that can block the flow of bloodthrough artificial blood vessels… more
Company: HEMEMICS BIOTECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Although platelets are a critical component in hemostasis, current methods for platelet storage severely limit their utility as a lifesaving blood component. In related work conducted to date, we have developed methodsto preserve mammalian cells in desiccated… more
Company: NANOCOR THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Congestive heart failure is a major cause of morbidity and mortality in the United States. While progress in conventional treatments is making steady and incremental gains to reduce heart failure mortality, there is a critical need to explore new therapeutic… more
Company: MED-CONDUIT, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The survival of patients with end-stage renal disease (ESRD) on hemodialysis is largely dependent upon the maintenance of vascular access. Yet catheter related blood stream infection remains one of the most important causes of sepsis and repeat hospital… more
Company: ACCEL DIAGNOSTICS Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: ****NOTICE: ABSTRACT EXTRACTED FROM APPLICATION FOR REPORTING CATEGORIES AND DISEASE CODING (RCDC). THIS TEXT HAS NOT BEEN PROOFED BY SRA. WHEN THE UPLOADED ABSTRACT IS NOT IN THE EXPECTED FORMAT, THE EXTRACTED TEXT MAY BE INCORRECT OR INCOMPLETE.**** Project Summary: The overall goal of the… more
Company: EMPHYMAB BIOTECH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Emphysema is a prevalent chronic obstructive pulmonary disease (COPD) induced predominantly by cigarette smoking through a complex mechanism that includes excessive apoptotic cell death of alveolar lung structural cellsand chronic inflammation and for which there… more
Company: RHEOMICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Population studies and drug research require a high-throughput measurement of clot stiffness, permeability. The single largest cause of death in the US over the latter half of the 20 century was and still is a thrombotic event: a clot in the heart, brain, or… more
Company: VIVAQUANT, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In-band artifact and noise present a major obstacle to extracting accurate, reliable, and repeatable information from ambulatory recordings of subcutaneous and surface ECGs. With more than 4 million patients a year experiencing ambulatory evaluations for cardiac… more
Company: CIRCADIAN MANAGEMENT, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): ZircLight: Spectrum-Specific Lighting for Shift Work Epidemiologic evidence has established that shift work exposure is associated with an array of adverse health consequences, including increased risk of cardiovasculardisease, gastrointestinal disease, and… more
Company: PROLUDE MEDICAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): ProHealing Drug Alternative for Coronary Drug Eluting Stents Our goal is to develop a novel, safer and more efficacious approach for treating Coronary Artery Disease, by incorporating a modulator of growth factor activity, PRM-100, within a Drug Eluting Stent… more
Company: FGH BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The Specific Aim of this proposal is to test the feasibility of using an orally available small molecule (FGH10019) to reduce obesity. Obesity contributes to the prevalence of many disease states and accounts for more than 25% of all health care costs in the US… more
Company: KOGNITO SOLUTIONS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Childhood obesity is a serious public health issue with significant health risks and high medical costs. Using motivational interviewing (MI) around nutrition and physical activity in the context o an office visit has shown positive results in terms of… more
Company: ORPRO THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Effective management of obstructive pulmonary diseases, especially Cystic Fibrosis (CF), represents a significant unmet medical need. Such diseases are characterized by thickened mucus that contributes to impaired lungfunction. This mucus barrier is composed… more
Company: NOVERATECH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The specific aims of this proposal are to use a newly developed intracellular energy delivery technique to enhance resuscitation, and to study the relationship between tissue high-energy phosphate supplementation and tissue necrosis and apoptosis during… more
Company: PARAGONIX TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Organ preservation and safe transport is a critical factor in transplantation medicine, but adequate preservation of human organs donated for transplantation poses a significant challenge. While significant progress hasbeen made in defining the principles… more
Company: RETIA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Cardiac output (CO) monitoring can improve the outcomes of critically ill patients via early detection and diagnosis of disease and goal-directed therapy. Yet, CO monitoring has sharply declined due to its invasiveness.Retia Medical will offer a device that… more
Company: SILICON BIODEVICES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Acute myocardial infarction (MI) is the biggest killer in the western world and is the cause of death for nearly 500,000 Americans each year. The symptoms of MI can be vague and non- specific; for this reason 6 to 9 million adults present to hospital Emergency… more
Company: ACXEND Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Nucleic acid analysis is the essential foundation of many biomedical research and diagnostic methods. Quantitative molecular diagnostic methods are critically dependent on the ability to stabilize the collected sampleprior to purification and analysis. While… more
Company: ZYDOC MEDICAL TRANSCRIPTION, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): This proposal aims to ensure the ability of NLP-Standalone-or-Hybrid Documentation, a method of EHR data capture involving Natural Language Processing and possibly also standard EHR data capture, to improve the usability of EHR by reducing documentation time,… more
Company: LUMENETEC, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The Climate Risk Analysis Division of Lumenetec, LLC, proposes to develop the Climate Change and Health Gateway (CCHG), an innovative and ground-breaking software tool that will radically enhance biomedical, health andclimate-change informatics. CCHG will empower… more
Company: BAUER LABS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Response to an Emergency Cesarean Delivery (ECD) at rural hospitals is complicated not only by inefficiencies in monitoring and early detection of fetal and/or maternal distress during labor, but by the conditions of the rural settin. Many rural hospitals lack… more
Company: PEOPLE DESIGNS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): This application addresses the development and translation of a medical technology to reduce health disparities within the priority area of chroni disease through the development and testing of an innovative web-based technology, Cookin' Up Health, for the… more
Company: DELPOR, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The objective of the proposed study is to develop a subcutaneous implant of risperidone which provides consistent therapeutic blood levels of the drug for 3 months. The benefits of such product include improved medication adherence, the ability to withdraw the… more
Company: NEUROSCOUTING, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Attention Deficit and Hyperactivity Disorder (ADHD) is a paramount public health concern - impacting more than 7% of children and 5% of the population as a whole. Although pharmacological interventions (e.g. psychostimulants) remain the main treatment for ADHD,… more
Displaying 5526 – 5550 of 5641 Awards
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