Abstract:DESCRIPTION (provided by applicant): The goal of this project is to rapidly discover biomarkers for Parkinson's Disease (PD) by defining the spectrum of causal genetic loci for PD, not only for the purpose of accurate diagnosis and risk stratification butalso in order to shed light on the… more
Abstract:DESCRIPTION (provided by applicant): Regeneration Matrix's technology, licensed from Georgia Tech, enables the design of a next generation nerve guide product to bridge large peripheral nerve gaps created due to trauma, tumor resection, or reconstructive surgery. The fundamental technology… more
Abstract:DESCRIPTION (provided by applicant): Hypothermia is a powerful neuroprotective treatment for ischemic injury and is indicated for use in cardiopulmonary bypass, cardiac arrest, and neonatal hypoxia. However, current methods induce systemic hypothermia which requires significant time and has… more
Abstract:DESCRIPTION (provided by applicant): Wide varieties of peripheral neuropathies accompanied by severe chronic pain are among the most common and debilitating human afflictions. Existing treatments have little long term benefits and often have severe side effects. Increasing evidence indicates that… more
Abstract:DESCRIPTION (provided by applicant): An absence of age-appropriate assessment technologies has hindered the ability of health, mental health, and school psychology professional to obtain and utilize self- report information from young children. This gap isproblematic for science and applied fields… more
Abstract:DESCRIPTION (provided by applicant): Our goal is to develop an In Vitro Diagnostic Multivariate Assay (IVDMIA) to distinguish Essential Thrombocythemia (ET) from non-clonal reactive thrombocytosis (RT) etiologies. ET represents a distinct subtype of myeloproliferative disorders, thrombocytosis,… more
Abstract:DESCRIPTION (provided by applicant): This STTR application is to develop and test for eventual clinical use a new strategy for tumor specific anticancer drug delivery. The technology, Clostridia-directed enzyme prodrug therapy, or CDEPT, exploits the factthat certain non-pathogenic bacteria of the… more
Abstract:DESCRIPTION (provided by applicant): Over 90% of cancer patients that enroll in Phase I or II clinical trials experience no benefit from the experimental therapies, yet are exposed to drug toxicity and other challenges related to treatment. For over 50 years, physicians have used patient-specific… more
Abstract:DESCRIPTION (provided by applicant): There is a significant unmet medical need to provide additional pharmacologic treatments for treatment and prevention of opioid overdose. This Fast Track STTR project proposes to apply drug delivery technologies to develop a novel use for a nasally delivered… more
Abstract:DESCRIPTION (provided by applicant): It is uniformly recognized that sedentariness - the sitting disease - is bad for the health of the nation. The solution to reversing sedentariness involves devising and disseminating real-world solutions to promote day-long physical activity and help people who… more
Abstract:DESCRIPTION (provided by applicant): This project aims to develop a commercial software product, VirtualDoseTM, for calculating and analyzing patient radiation doses from x-ray computed tomography (CT) examinations. Despite its essential role in radiology, CT is responsible for raising the… more
Abstract:DESCRIPTION (provided by applicant): A major cause of morbidity and mortality in cardiovascular surgery is excessive bleeding post- operatively, which is commonly managed by pharmacologically modifying clot degradation (fibrinolysis), through inhibition of plasmin activity (PLact). However,… more
Abstract:DESCRIPTION (provided by applicant): Among the currently available techniques for high throughput proteomics, protein microarrays have the greatest prospects to revolutionize molecular diagnostics for early detection, diagnosis, treatment, prognosis and monitoring clinical response. However, protein… more
Abstract:DESCRIPTION (provided by applicant): In this Phase II STTR project, Vestan Medical Imaging, Inc. will complete the development and clinical evaluation of its proprietary formulation of a fluorescent drug and new medical devices for Sentinel Lymph Node (SLN) biopsy for the surgical treatment of… more
Abstract:DESCRIPTION (provided by applicant): Highly Active Anti-Retroviral Therapy (HAART) used to treat HIV/AIDS has serious side-effects, including metabolic complications from mitochondrial toxicities that can be life-threatening, and limit effectiveness and patient compliance. Adverse metabolic effects… more
Abstract:Many steering mirrors have been developed over the years, but never has one been explicitly designed for high dose radiation environments or long-term space operations. As a result, deployed spaced based optical systems for line-of-sight stabilization or beam control have not benefited from the… more
Abstract:The contractor proposes to: 1) develop gel-based formulations that allow the feeding of mice with a variety of altered diets, 2) determine the level of caloric restriction necessary for protection against chemotherapy and identify dietary components whose deficiency is sufficient to provide a… more
Abstract:Quantum cryptography, and in particular Quantum Key Distribution (QKD) is a secure method to distribute a secret key between two distant authorized partners whose security is based on the laws of physics. Current public key cryptosystems have not been proven to be secure and are based on the… more
Abstract:SA Photonics and the Georgia Tech Research Institute (GTRI) are please to propose the development of MIMO SAR/GMTI techniques. The approach is to leverage the extensive amount of research that has been conducted in an academic setting and to assess the feasibility of the transition of these… more
Abstract:As more countries hostile to the U.S. gain access to and develop ballistic missile technology, the threat of attack against U.S. territory or its allies steadily increases. The continued advancement of Ballistic Missile Defense System (BMDS) interceptors to support longer range missions on more… more
Abstract:SA Photonics' CORONA architecture is a photonic multi-beam beam former. It supports large phase array size of 40,000 to 400,000 elements with scanning angle of +/- 60 degrees. It supports multi-beam operation of minimum 10 beams with wide frequency range of over 2 octaves covering X band as well as… more
Abstract:Gyros are commonly used to measure the rotation of antenna pedestal platforms to enable very accurate antenna pointing. These gyros need to have very good angular stability and work over uncontrolled platform environment. But gyros currently deployed in this application space lack the needed long… more
Abstract:SA Photonics is pleased to propose the SENTRY closely spaced object (CS0) space situational awareness system. THe SENTRY system leverages SA Photonics'' technology in LIDAR, LIVAR, and free space optical communincation by employing: SA Photonics'' innovative light source technology, the Acu-Point… more
Abstract:The need for higher bandwidth communications supporting video as well as data transmission to the warfighter is driving the development of satellite-based free space lasercom. However, the current state-of-the-art in laser transmitter technology is mainly directed at fiber optics systems which have… more
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