Abstract:Ziva Corporation proposes to develop and demonstrate an innovative ultra-wide field of view imaging system that incorporates foveated zoom capability and is fabricated without having multiple cameras, bulky gimbals, or large mechanically moving parts. Ziva has developed under IR&D a unique… more
Abstract:In this Phase SBIR II proposal, Ziva proposes to demonstrate a prototype large angle 2-D scanner featuring integrated imager stabilization with >10X lower SWaP (size, weight, power) compared to conventional technologies. This meso-hydraulic-based technology is unique in that: Large scan angles are… more
Abstract:OBJECTIVE: A prototype unit capable of detecting trace amounts of low-volatility chemicals from distances of 25+ meters. DESCRIPTION: The ability to detect trace chemicals from safe distances is critical. When those chemicals are low-volatility (as they are for many explosives), the difficulty of… more
Abstract:CFD-based design-oriented (DO) steady/unsteady aerodynamic analysis tools for Aeroelastic / Aeroservoelastic (AE/ASE) evaluation lag significantly behind other multidisciplinary design optimization (MDO) developments for flight vehicle design. In practically all studies to date involving… more
Abstract:ZONA Technology, Inc. (ZONA) proposes to develop an on-line flutter prediction tool for wind tunnel model using the parameter varying estimation (PVE) technique to ensure the safety of the flutter model as well as the wind tunnel system. This tool will be applied to rapidly evaluate parameters, such… more
Abstract:Multidisciplinary design and optimization (MDO) tools developed to perform multi-disciplinary analysis based on low fidelity computation methods have been used in aircraft conceptual design for decades. These tools have been proven very effective for simple problems and mostly have been developed… more
Abstract:ZONA Technology, Inc. (ZONA) proposes to develop an integrated flight dynamics simulation capability with nonlinear aeroelastic interactions by combining a flight dynamics model and an added-on nonlinear aeroelastic solver in a Simulink environment. This nonlinear aeroelastic solver is generated by… more
Abstract:An efficient and accurate software package named ZMGP (ZONA Multi-scale Gaskinetic/Particle simulation package) is proposed as a 3D tool to predict the lunar dust trajectory and crater formation process when a retro-rocket lands on the lunar surface. ZMGP has many special features including: 1, the… more
Abstract:Multidisciplinary design, analysis, and optimization (MDAO) tools today possess limited disciplines with little fidelity modeling capability. These tools are typically developed as a single large software application that performs analysis for all disciplines but has little or no capability to… more
Abstract:This SBIR Phase II project will develop a method to convert the byproduct glycerol to a value-added co-product, xylitol, thereby helping to reduce the costs associated with biodiesel production. The anticipated result is a scalable process capable of converting crude glycerol to xylitol in a single… more
Abstract:This Small Business Innovation Research Phase I project seeks to enhance the capability of an instrument for identifying and quantifying bio-molecules, cells, microbes, and their interactions. The goal of the project is to demonstrate the feasibility of a Surface Plasmon Resonance (SPR) biosensor… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will demonstrate the production of robust, versatile probes based on Bioluminescence Resonance Energy Transfer to Quantum Dots (BRET-Qdot
Abstract:There is a clear need to better define patient-specific treatment strategies for the use of both standard and novel therapies for treating multiple myeloma. Eutropics is uniquely positioned to improve therapy efficacy for multiple myeloma by using a proprietary assay that provides a novel… more
Abstract:DESCRIPTION (provided by applicant): The Bcl-2 family proteins are key effectors of cancers. Recent studies indicate that Myeloma cell factor-1 (Mcl-1), a member of this protein family, is a key regulator of lymphoid cancers including Multiple Myeloma (MM)
, Non-Hodgkin's Lymphoma (NHL), and other… more
Abstract:The Small Business Research and Development Enhancement Act of 1992 requires the agencies of the Public Health Service, Department of Health and Human Services and certain other federal agencies to reserve 2.5% of their current fiscal year extramural budgets for research or research and… more
Abstract:DESCRIPTION (provided by applicant): Metastatic bone cancer and multiple myeloma affects over 600,000 people every year in the United States and cause progressive bone destruction that results in severe pain, fractures, and the inability to walk. Patients
usually present with incapacitating pain… more
Abstract:Ultra High Temperature Ceramics (UHTC's) such as zirconium and hafnium diboride based composites are of particular interest for hypersonic leading edges due to their extreme refractoriness. Successful integration into hypersonic structures will require high strength / high temperature joints to… more
Abstract:A method of inducing non-contact creep deformation was demonstrated in ultra high temperature diborides via electro-magnetic forces. The Phase II effort will focus on refining the Electro-Magnetic Mechanical Apparatus to exhibit better control of test variables and have a higher degree of… more
Abstract:This Small Business Technology Transfer Phase I project seeks to develop biomimetic structures in engineering ceramics based on the damage-tolerant sea shell micro-architecture. Poor damage tolerance of engineering ceramics leads to catastrophic failure modes under stress, which restricts their… more
Abstract:The Phase I SBIR program was extremely successful in that we demonstrated the feasibility of using nano-composite cathodes of metal oxide and lithium iron phosphate to provide lithium-ion cells with high energy, high power, abuse tolerance, improved low temperature performance, and good cycle life,… more
Abstract:The objective of the proposed work is to validate the concept of an injection moldable in-situ reinforced barium alumino silicate (IRBAS) missile radome using a Hotblox pre-ceramic siloxane binder system. In Phase I, ATC will optimize formulation, mixing and molding process development. ATC will… more
Abstract:The InAs/InGaSb Strained Layer Superlattice (SLS) system is developing rapidly and is now finally poised to seriously challenge HgCdTe as the dominant technology for mid- and long-wave detection. SLS structures have a number of practical and theoretical advantages over HgCdTe materials, including… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop device structures for infrared sensor applications using lead chalcogenides. This system has reduced cooling requirements over other high performance infrared materials (such as HgCdTe) resulting from their reduced Auger… more
Abstract:Biofuels in the US consist almost entirely of grain ethanol from corn. This has created concern in that a competition for grain for feed and fuel can cause an increase in price which in turn can limit the potential for its use. At best, corn can only account for 25% of replacement fuels. To meet the… more
Abstract:DESCRIPTION (provided by applicant): Complete achromatopsia is an inherited retinal disorder characterized by severely reduced visual acuity, nystagmus, severe photophobia, a small central scotoma, eccentric fixation, and complete loss of color discrimina
tion. In 50% of patients with achromatopsia… more
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