Abstract:Third generation x-ray synchrotron facilities, such as Argonne National Laboratory¿s Advanced Photon Source, create high-brilliance x-ray beams that are focused to small spot sizes on a wide variety of materials and biological samples. The efficient use of these expensive facilities requires that… more
Abstract:DESCRIPTION (provided by applicant): Despite their unique advantages and great promise for elucidating the structure of proteins, neutron techniques have been underutilized compared to X-ray measurement techniques, primarily because of the lack of adequate
neutron sources and suitable imaging… more
Abstract:DESCRIPTION (provided by applicant): Neutron techniques complement X-ray diffraction techniques in their ability to precisely locate hydrogen and light atoms in various materials. This information is critical for determining the structure and function of p
roteins and for the discovery of biological… more
Abstract:Scintillation detectors, consisting of inorganic scintillation crystals coupled to photomultiplier tubes (PMTs), are an important element of medical imaging applications such as positron emission tomography (PET). However, the performance of these systems is limited by the properties of the… more
Abstract:Single photon emission computed tomography (SPECT) is a powerful, noninvasive medical imaging modality that mathematically reconstructs the three dimensional distribution of a radionuclide throughout the body of a human patient or research animal. At present, the performance of available SPECT… more
Abstract:DESCRIPTION (provided by applicant): Recent extraordinary developments in synchrotron radiation sources have enabled the growth of powerful research techniques such as time-resolved X-ray diffraction studies, essential for understanding dynamic biological
phenomena and recovering phase information… more
Abstract:Proliferation of nuclear weapons is a serious threat in the world today. One way to
determine the presence of nuclear weapons is to detect neutrons emitted by special
nuclear material (SNM) such as highly enriched uranium and weapons grade plutonium.
The purpose of this project is to develop… more
Abstract:Current state-of-the-art X-ray imaging detectors use energy integration, where the simple integration of X-ray events during the exposure period forms images. Unfortunately, such indiscriminate operation is sub-optimal for digital radiography or CT imaging because of its inability to reject scatter… more
Abstract:The crude oil will be depleted within 40 years, alternative fuels have to be developed to drive our transportation systems, and biodiesel appears to be the most promising fuel of the future. Biodiesel is renewable, non-toxic, and biodegradable, it can be used in existing diesel engines without… more
Abstract:The team of Velox Semiconductor Corporation (Velox) and Rensselaer Polytechnic Institute (RPI), proposes to demonstrate the feasibility of using a single, monolithic, all-GaN integrated Diode(s) Driven Gate (DDG) HFET to achieve normally-off device operation with specifications required for Navy… more
Abstract:GaN (Gallium Nitride) High Electron Mobility Transistor (HFET) devices face severe thermal control problems as a result of high power densities which result from the need for more power and the ongoing reduction in geometries of individual devices. The device lattice temperature increases under high… more
Abstract:Currently there is no affordable military band on-the-move non-line-of-sight (NLOS) or beyond-line-of-sight (BLOS)communications capability available for land vehicles, helicopters, boats or small UAVs. The current state-of-the-art in Satellite-On-the-Move (SOTM) terminals for Blue Force Tracking… more
Abstract:High capacity Thermal Energy Storage (TES) systems that can rapidly absorb peak waste heat using phase change, liquid to vapor, dissipating it gradually during normal operation, are the most ideal and most compact Thermal Management (TM) systems possible for advanced weapon systems. such as. These… more
Abstract:Open cell foam, which provides the highest heat transfer surface areas per unit volume, is considered as an excellent heat exchanger core material. Pyrolytic Carbon coated reticulated vitreous carbon (RVC) foam, developed by Allcomp, which offers highly conductive foam ligaments and is available in… more
Abstract:The next generation of silicon-based detectors for tracking charged-particles in high energy physics experiments will impose demanding requirements. One of these requirements involves the need for thermally efficient, low mass, dimensionally-stable support structures exposed to high radiation… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is to develop ultra-sensitive ELISA (Enzyme-Linked ImmunoSorbent Assay) methods for quantification of HIV p24 antigen. At present, the p24 antigen test is relatively insensitive, being abl
e to detect only 5- 10 pg/ml. This quantity… more
Abstract:DESCRIPTION (provided by applicant): Currently buprenorphine (BUP) is used in the treatment of opioid abuse and for pain management. It can also be used improperly and abused as an opioid. In the United States, buprenorphine is marketed in sublingual and i
njectable forms. While the drug provides… more
Abstract:The objective of this Phase II SBIR effort is to develop and demonstrate a low cost, lightweight, two independent simultaneous transmit beam antenna for use in SATCOM systems like the Transformational Satellite Communications System (TSAT) downlink. The current MILSATCOM system supports one… more
Abstract:Recent developments of advanced hybrid metallic structural concepts have been extremely promising for durable light-weight and ultra-long fatigue life large transport aircraft. The Alpha STAR team (Alcoa, SWRI, and Virginia Tech) proposes to extend the validated Fiber Metal Laminate (FML) high… more
Abstract:DESCRIPTION (provided by applicant): Awareness of the enormous advantages of computerized adaptive testing (CAT) in an item response theory framework (IRT) is growing rapidly in the behavioral research community. CAT has the capacity to significantly reduc
e respondent burden without losing… more
Abstract:DESCRIPTION (provided by applicant): Targeted Pb-212 therapy in preclinical animal tests has shown a cure in groups receiving the highest dose of this therapy. Scaling the dose that was most efficacious in animal studies to people would bring the human dos
e required from 50 to 100 mCi. This… more
Abstract:In this proposal, AlphaSense, Inc. (AI) and the Pennsylvania State University (PSU) detail the development of a novel noninvasive microwave sensor to quantify the DoS in marine aluminum alloys. The key innovations of this proposal include the following: a) DoS quantifications based on the… more
Abstract:In this proposal, Alphasense, Inc. details the development of a novel microwave NDE sensor for defect inspections in silicon nitride bearing balls. The key innovations of this proposal include the following: a) the use of the spherical bearing ball as a dielectric resonator, thus enabling us to… more
Abstract:In this proposal, AlphaSense, Inc. proposes to develop an innovative real time probe for online monitoring of plastic bonded explosive manufacturing process. Key innovations of the proposed sensor probe include: a) the use of a white light interferometer (WLI) to form real time images of the… more
Abstract:The SBIR Phase I proposal is designed to improve the high end temperature performance of Altairnano''''s nano Lithium titanate batteries and will develop an equivalent circuit model capturing the transient dynamics of Altairnano's 50 Ah cell. Altairnano will study the effects of various materials… more
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