Abstract:DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) imaging systems used in Nuclear Medicine can suffer from loss of spatial resolution due to parallax effects, called radial elongation. A scintillation detector that allows depth-of- in
teraction (DOI) determination would be an… more
Abstract:DESCRIPTION (provided by applicant): High Resolution Detectors for Single Photon Cardiac Imaging Single photon emission computed tomography (SPECT) is a powerful, noninvasive medical imaging modality that mathematically reconstructs the three dimensional d
istribution of a radionuclide throughout… more
Abstract:DESCRIPTION (provided by applicant): Venous catheters play critical roles in the administration of chemotherapy, antibiotics, blood, blood products and total parenteral nutrition essential for the successful treatment of many chronic afflictions. Recent ad
vances in catheter technology have enabled… more
Abstract:DESCRIPTION (provided by applicant): The focus of the proposal is in the area of breast cancer imaging and tumor characterization using oxygen sensitive phosphorescent labels and hybrid imaging modality. We propose to use simultaneous diffuse optical tomog
raphy (DOT) and magnetic resonance imaging… more
Abstract:DESCRIPTION (provided by applicant): While many exotic new scintillation materials are now being developed, few even come close to CsI:Tl in performance and versatility. Widely available commercially at low cost, CsI:Tl not only has superb scintillation ef
ficiency, but also can readily be… more
Abstract:DESCRIPTION (provided by applicant): Microfluidic devices are a promising, emerging technology for molecular imaging studies. These chips can contain a variety of microcircuitry and microwells, and are capable of manipulating nanoliter samples of reagents
and solvents. The microfluidic chips have… more
Abstract:DESCRIPTION (provided by applicant): Some of the most useful tools for diagnosis and understanding of blinding retinal diseases rely on the use of spectral reflectance. Improvements to these tools, especially over the past decade, have greatly advanced our
ability to achieve extremely… more
Abstract:Nuclear physics investigations require photodetectors that operate in harsh conditions (e.g., temperatures of 5 K and below, and magnetic fields greater than 1 T); yet existing methods of photodetection cannot provide the needed quality of data at a reasonable cost. This project will develop a… more
Abstract:Inorganic scintillation crystals are a very important element of the current and the next generation experiments in nuclear and particle physics. Performance of the nuclear physics detection systems is often limited by the properties of scintillators available for neutron and gamma ray detection. … more
Abstract:DESCRIPTION (provided by applicant): Venous catheters play critical roles in the administration of chemotherapy, antibiotics, blood, blood products and total parenteral nutrition essential for the successful treatment of many chronic afflictions. Recent ad
vances in catheter technology have enabled… more
Abstract:Cadmium zinc telluride (CZT) detectors have the potential to be a powerful and versatile tool in the tracking and control of nuclear materials. However, despite well over a decade of development, yield of spectrometer grade material remains low. This project will investigate the traveling heater… more
Abstract:X-ray detector arrays with high energy resolution, high sensitivity and high count-rate performance are required for synchrotron beamline studies. However, in many studies conducted with synchrotron beamlines, the characteristics of available X-ray detectors limit the overall system performance. … more
Abstract:Microfluidic chips, fabricated from low cost polymers, are a promising, emerging technology for synthesis and study of new molecular imaging probes. These chips can contain a variety of microcircuitry and microwells, and are capable of manipulating nanoliter samples of reagents and solvents. The… more
Abstract:Scintillation detectors, consisting of inorganic scintillation crystals coupled to photomultipliers, are an important element of medical imaging applications such as positron emission tomography (PET). Performance as well as cost of these systems is limited by the properties of the scintillation… more
Abstract:Gamma-ray spectrometers based on lanthanide halide scintillators are a very promising class of detectors for nuclear nonproliferation monitoring. They provide excellent energy resolution and fast response. However, the growth of large crystals of lanthanide halide scintillators using traditional… more
Abstract:The development of new high-intensity neutron sources such as the Spallation Neutron Source (SNS) will place demanding requirements on detector performance, because current state-of-the-art detectors are limited by the characteristics of the phosphor screen used to convert the incident neutron flux… more
Abstract:Depth-of-Interaction (DOI) encoding is an important requirement in clinical as well as small animal Positron Emission Tomography (PET). At present, almost all commercial PET scanners do not have DOI encoding capability, and, as a result, these scanners exhibit parallax error, which degrades their… more
Abstract:Positron Emission Tomography (PET) is a functional imaging technique with the potential to quantify the rates of biological processes in vivo. PET imaging can provide diagnosis for symptoms of diseases such as Alzheimer¿s disease, head trauma, cancer, and stroke. However, the performance of… more
Abstract:Optimized extraction of heat content from various blends of coal fuel, in combination with a reduction in harmful constituents and byproducts, will be necessary if reliance on coal energy is desired. Therefore, it is important to have a real-time instrument that (1) provides relevant information… more
Abstract:Most nuclear physics experiments use PMTs coupled to scintillators, which require a readout using BNC cables, HV cables, HV suppliers, analog-to-digital converters (ADCs), and possibly additional modular electronics and mainframes for signal processing. These items tend to account for a significant… more
Abstract:Current and next generation experiments in nuclear and particle physics require detectors with high signal-to-noise ratio, fast response, accurate energy information and high spatial resolution. This project will investigate a compact detector design that can be operated with very high gain. This… more
Abstract:Single photon emission computed tomography (SPECT) is a powerful, noninvasive medical imaging modality that mathematically reconstructs the three dimensional distribution of a radionuclide throughout the body of a human patient or research animal. At present, the performance of available SPECT… more
Abstract:Positron Emission Tomography (PET) is a powerful imaging technique with a potential to quantify the rates of biological processes in vivo. However, the performance of PET systems is limited by presently available detector technology. Next generation gamma-ray detectors will be based on bright, fast… more
Abstract:With the increase in the number of new neutron sources, stationary as well as portable, there has been growing utilization of neutrons in materials science and other fields. However, available neutron detectors are not able to extract the full potential of the new neutron sources being built. This… more
Abstract:Recent developments in synchrotron radiation sources have enabled the growth of powerful techniques, such as time-resolved X-ray diffraction for understanding dynamic biological phenomena and the Multi-wavelength Anomalous Dispersion (MAD) method for recovering phase information in X-ray… more
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