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Year:2008
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Displaying 326 – 350 of 6238 Awards
Company: AET, Inc. Agency/Program/Year/Phase: DOD / STTR / 2008 / 2
Abstract: The goal of this program is to develop high-speed interceptor communications solutions that are hardened to space and nuclear radiation, including high altitude nuclear explosions (HANEs). AET will design and develop lateral emission-based diamond integrated logic circuits that have been… more
Company: AET, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2008 / 2
Abstract: The thrust of this program is to perform research and development that will result in diamond sensors that can be integrated with a silicon-based integrated circuit for incorporation into the skin of cognitive missiles and other air vehicles. These sensors will be fabricated on a silicon chip to… more
Company: AETION TECHNOLOGIES LLC Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: Significant challenges exist related to smartly interviewing multiple people to assess eyewitness accounts and judge how truthful a source is. Aetion proposes applying a powerful form of inference called abduction to help intelligently interview multiple people and compare their corresponding… more
Company: AFASCI, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Recent surveys indicate that approximately 26 - 27 million individuals in the US suffer from moderate to severe chronic pain. A key pathophysiology of chronic pain is neurogenic inflammation, which is primarily elicited by activation of unmyelinated sensory… more
Company: AFCO Systems Development Inc Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: ASD proposes to develop and integrate an Application Partitioning Toolkit (APT). The APT provides an environment for the partitioning, analysis and the construction of a distributed application. The initial target of the toolkit is the OSD06-IA7 secure coprocessor and application monitor. The… more
Company: AFCO Systems Development Inc Agency/Program/Year/Phase: DOD / SBIR / 2008 / 2
Abstract: SHIELD is a defense-in-depth multi-layered architecture that is suitable for a GIG end-node based upon COTS technology. The architecture contains the following layers: 1. A set of application software and data protection techniques, which utilize an out-of-band secure coprocessor and its… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Over 700,000 surgical hernia repairs are performed each year in the United States and despite recent advances, a significant rate of recurrence persists. The incorporation of biocompatable mesh to strengthen the abdomi nal fascia has largely replaced… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Ventriculoperitoneal (VP) shunts are used to treat pediatric and neonatal hydrocephalus in severe cases, representing approximately 1/3rd of affected infants. Due to the high susceptibility for infection and mechanica l breakdown, the failure rate of VP shunts… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): The Centers for Disease Control estimates that as many as 2 million people contract infections in hospitals each year, with as many as 100,000 deaths. Approximately 1/4 of hospital related infections (~500,000) are surg ical site infections. For each single… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infectio ns, which arise from the establishment of… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Summary Improving cardiovascular implants to reduce thrombosis and other confounds has been a long-term goal of medical science. Grafts and endovascular stents have been recently modified to include new materials, atta ched cells or drug-eluting polymers to make… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years of age have at least moderate periodontitis with over a quarter having lost their teeth, resulting in serious health a nd quality of life repercussions. Bone… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infectio ns, which arise from the establishment of… more
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): Growth factors are potent signaling molecules, initiating essential cellular programs for differentiation, proliferation and survival. Only recently have large molecules like growth factors, been employed to enhance the efficacy and specificity of medical… more
Company: AFFOMIX, INC. Agency/Program/Year/Phase: HHS / STTR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Affomix would like to commercialize antibody chips to enable researchers to study the human proteome. Currently, researchers use gene chips as a surrogate means to estimate the concentration of the vast variety of pro teins in cells and tissues. But given the… more
Company: AFFOMIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Nearly 20 years ago, partially as a response to leveraging the genomics research the NIH invested in the development of gene array technologies. These gene chips' enabled great breakthroughs in our understanding of the underlying biological processes that occur… more
Company: AFG BIOSOLUTIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): The deliberate release of Bacillus anthracis spores remains an imminent threat both in terms of bioterrorism and biowarfare. Individuals who inhale these spores are at extreme risk of infection and death from anthrax. C urrent prophylaxis and therapy in the event… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: Rapid detection of the total trihalomethanes (TTHM) in treated drinking water is essential for compliance with the Environmental Protection Agency's (EPA) Stage 2 Disinfectants and Disinfection Byproducts (DBP) Rule, which limits the maximum contaminant level of TTHM in drinking water to 80 parts… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by investigator): Lyme disease, caused by the gram-negative spirochete Borrelia burgdorferi and transmitted by Ixodid tick species, is the leading vector-borne infectious disease in the United States, with a steady rise in the number of cases reported each year. The most… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: The key to effective management of malaria is accurate diagnosis that is also rapid. The "gold standard" microscopy is time-consuming and labor-intensive and suffers from retirement of microscopic diagnostic experts and inaccurate slide reading. A field-deployable diagnostic method that is… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can… more
Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2008 / 1
Abstract: Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and… more
Company: AGENNIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): This project aims to develop talactoferrin (TLF, recombinant human lactoferrin) as a therapeutic agent to treat prematurely born neonates. The treatment will be given orally shortly after birth to prevent nosocomial inf ections (NIs) due to abnormal bacterial… more
Company: AGENNIX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): Severe sepsis is a major cause of morbidity and mortality throughout the world. It is the leading cause of death in non-coronary intensive care units (ICUs) in the United States, with more than 750,000 cases occurring e very year. This means that in the United… more
Company: AGILE GENOMICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Signal transduction systems regulate the majority of cellular activities including the metabolism, development, host-recognition, biofilm production, virulence, and antibiotic resistance of human pathogens. Thus, knowle dge of the proteins and interactions that… more
Displaying 326 – 350 of 6238 Awards
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