Abstract:DESCRIPTION: The specific objective of this STTR Phase II research and development project is to provide an optimized cellular therapy regimen for treating hypoxic-ischemic (HI) injury and its related outcomes in neonates. Pre- clinical studies performed i
n a rat pup model of HI injury as part of… more
Abstract:First Marine International, in their latest benchmarking study of the global shipbuilding industry, identified production preparation as one of the key items preventing U.S. shipbuilders from reaching world quality status. These problems are partially caused by a lack of standardized tools to… more
Abstract:One of the most significant challenges facing the Defense Industry today is the lack of interoperability between software applications. Weapons systems data is voluminous, complex, and distributed across many disparate applications. Typically, only a few of these applications are truly integrated… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project develops a pretreatment process for biomass that will be used as feedstock for making biofuels, thereby solving a significant problem in this process. Before plant and tree material (biomass) can be used to produce biofuels, or… more
Abstract:DESCRIPTION (provided by applicant): Laboratory animals are often subjected to various painful surgical procedures as well as non-surgical procedures. It is the ethical obligation of all research personnel involved with the care and use of laboratory anima
ls to reduce or preferably eliminate pain… more
Abstract:The Small Business Innovation Research (SBIR) Phase I Project will develop a flexible, reusable, two-sided, dry, thermally and electrically conductive adhesive film consisting of a dense vertically aligned multiwalled carbon nanotubes (CNT) embedded in a flexible polymer matrix. The polymer chosen… more
Abstract:As the Air Force moves toward the deployment of many smaller satellites, it would be useful to develop smaller versions of SSUSI and GUVI imagers to take advantage of these multiple platforms, so that global measurements could become an operational reality. The goal of the Phase I effort proposed… more
Abstract:We propose to investigate under Phase-I of the STTR Program FY07 the development of space weather sensor networks including the next-generation of GPS space weather monitors, the network interfaces for internet and remote operation, and system-wide analysis algorithms to validate and calibrate the… more
Abstract:Accurate real-time knowledge of the bottomside ionosphere is necessary for covert HF communications, near vertical incidence sounding, and geolocation of HF transmitters. Sky-wave TDOA geolocation is the "holy grail" of HF geolocation techniques due to its passive nature, low cost, and easy… more
Abstract:"The United States floriculture industry reached a total of $5.6 billion in domestic consumption in
2002 with an additional $111 million in exports. As the industry continues to move towards
mechanized harvesting in order to increase production, the potential for bulb injury and resulting
Abstract:We propose to build and evaluate NDIR Analyzers that can observe eddy covariance flux of CO2 from unmanned airborne platforms. For both phases, a total of four analyzers are to be evaluated for their nose (ppb rms, Dry Mole Fraction) and susceptibility to artifacts on platform. We present original… more
Abstract:Fine-scale, well-calibrated probabilistic weather forecasts are increasingly in demand for such weather-critical applications as battlespace management, and accurate prediction of high-value airborne operations. Built upon the Phase I effort we have just completed, the principal objective of this… more
Abstract:This Phase I Small Business Innovation Research (SBIR) proposal focuses on the development of a complete lab-on-chip analysis system based on open channel capillary chromatography, to provide rapid, real-time identification and quantitation of production process components, using an alternative to… more
Abstract:DESCRIPTION (provided by applicant): The aim of this research is to develop a locus-specific DNA amplification process suitable for highly multiplexed detection of pathogenic mycobacteria in environmental samples. Specifically, this project aims to develo
p an assay to identify the presence of… more
Abstract:This Small Business Innovation Research Phase I project proposes to develop a high-speed and flexible prototype Atomic Layer Deposition (ALD) system suitable for its adaptation to an in-situ precursor generation and a plasma source to develop novel Gallium Nitride (GaN) thin film processes for… more
Abstract:The computational burden of simulating incoherent imaging of large extended objects, through high turbulence, using conventional wave optics simulation techniques is very significant. This simulation capability is crucial for evaluating performance of such systems as the Advanced Tactical Laser… more
Abstract:Knowledge of key parameters of optical turbulence is essential for prediction of optical performance in both imaging and transmitting applications. Optimal techniques for compensation of turbulence effects are only as good as the knowledge of the turbulence environment. The basic required… more
Abstract:DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones employ a
supra-aural design that has several… more
Abstract:DESCRIPTION (provided by applicant): The number of patients treated for antibiotics-resistant infections has increased drastically in recent years. What started as a problem primarily associated with hospital-acquired Enterococcus infections, has not only
moved into the general community, but also… more
Abstract:Demonstration of highly efficient 1000W amplifier (405-450 MHz) is proposed in the two-phase program. The first phase is a feasibility phase where a 100W 70% efficiency block amplifier will be demonstrated using GaN HEMT devices and Class F circuit design technology. In phase 2 of the program, the… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this research is to reduce or eliminate deafness due to certain diseases of the inner ear by developing sustained release formulations for anti-inflammatory drugs which can be implanted directly in
to the inner ear. The initial project will… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this research is to reduce toxicity and graft rejection due to dosing problems with the calcineurin inhibitors by developing sustained release subcutaneous injectable formulations for the drugs tac
rolimus and cyclosporine. Substantial… more
Abstract:DESCRIPTION (provided by applicant): The broad long term goal of this work is to develop sustained release subcutaneous drug delivery systems in order to achieve a more continuous dopaminergic stimulation in the treatment of Parkinson's Disease (PD). The i
mmediate goal of this project is to develop… more
Abstract:Aurora Flight Sciences proposes to apply algorithms for cooperative tasking of multiple unmanned vehicles, which have been significantly matured in UAVs, to a variety of USV littoral search, inspection, and force protection missions. Because of our mature starting point, the focus will be to… more
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