Abstract:DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) is a chronic disease, characterized mainly by inflammation of the lining, or synovium, of the joints. It can lead to long-term joint damage, resulting in chronic pain, loss of function and dis
ability. Approximately 2.1 million people… more
Abstract:DESCRIPTION (provided by applicant): It is estimated that the annual incidence of spinal cord injury (SCI), not including persons who die at the scene of the accident, is approximately 11,000 cases per year. The number of patients currently affected by SCI
in the United States has been estimated at… more
Abstract:The proposed research effort recognizes the growing importance of open-source intelligence for evolving military operations, and is designed to enhance the capability of intelligence analysts to develop inferences from open information sources that can be acted on with confidence in the face of… more
Abstract:Phases I through III of this SBIR are about developing and implementing a new technology for creating "Tactical User Interfaces" (TUIs) that reduce manpower requirements and increase watchstander performance. Phase I applied this multi-faceted "TUI Technology" to passive sensors, especially ASW. … more
Abstract:Game-based training (GBT) has been touted as a promising medium for achieving improved training outcomes and heightened learner motivation, particularly in military training environments. However, there is little empirical research upon which to make informed decisions about when, where, or even if… more
Abstract:This project will develop an innovative training system to deliver advanced instruction in HQ staff officer competencies that will produce effective joint task force (JTF) teams. Stalwart (System of Training to Accelerate Learning in Joint Warfighting Teams) blends on-line training with small-team… more
Abstract:Phase I entails a systematic investigation of handheld devices and wiki-based information sharing in relation to the needs and requirements of PSYOP soldiers in order to produce an optimal design of the Mobile Intelligence Data Acquisition System (MIDAS). The investigation will thoroughly cover… more
Abstract:The aim of this project is to build a handheld Portable Maintenance Support Tool (PMST) incorporating a Micro Controller Unit providing wireless interface between sensor networks and portable computer data bases for materials management and monitoring. The PMST will further incorporate an open… more
Abstract:The feasibility of ANP's proposed seld-calibrated rapid test forf AChE inhibitors has been clearly shown in Phase I. Its compatability with ANP's handheld reader for immuno-assay based threat agent rapid testing has been confirmed. Phase II will finalize the design for robustness, full integration… more
Abstract:This Small Business Innovation Research Phase I project is directed towards development of an innovative technology for fabrication of high-efficiency thin film nanocomposite photovoltaic materials and solar cells taking advantage of the recently discovered breakthrough effect of carrier… more
Abstract:This project develops a multi modal computer interface device and authoring toolkit for the development of age appropriate computer learning for children and adolescents with developmental delays.
Abstract:One of the major questions simulation designers must address is "which components of fidelity have the greatest impact on transfer of training?" In theory, the notion is that the higher the simulation fidelity, the more likely an operator is to behave in a similar fashion within the simulation as… more
Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase II project is to develop robot-based content to target upper extremity movement therapy goals and evaluate the clinical efficacy of the CosmoBot Robotics System as a therapy
intervention for children diagnosed with… more
Abstract:DESCRIPTION (provided by applicant): The goal of this application is to develop imageable tumor-targeting bacteria that can cure tumors without progressive infection of the host. Previous experiments by others employed anaerobic microorganisms for cancer t
herapy. Target specificity appeared largely… more
Abstract:This effort will identify and model the critical functional/physical system and subsystem requirements, components, subcomponents, and key performance parameters for a shock response spectrum test facility that is capable of multi-axis fuze testing.
Abstract:This proposal defines a pathway to safely carry and dispense gasoline and other highly volatile fuels within enclosed spaces aboard U.S. Navy ships, and in particular, the Littoral Combat Ship. This is necessary to accommodate the Combat Rubber Raiding Craft (CRRC) employed by SEAL detachments and… more
Abstract:We will build a versatile, compact, rugged and low-power laser system for use in rubidium Bose-Einstein condensate (BEC) experimentation and sensors. Existing commercial laser systems available for driving 780 nm rubidium transitions have very limited numbers of optical frequency outputs. … more
Abstract:DESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection is a major cause of liver disease throughout the world. Existing therapies are suboptimal and the search for alternative therapies is imperative. Recent years have seen a tremendous inc
rease in efforts to identify more effective… more
Abstract:DESCRIPTION (provided by applicant): A novel bioprocess platform, involving synthesis of peptide and protein biopharmaceutical products as fusions with a synthetic anchor protein in bacteria, and subsequent proteolytic cleavage, will be developed. The un
ique features of the system allow for the… more
Abstract:Many NASA space and Earth programs in the infrared range 1060-1550 nm are limited by the detector performance that require long exposure time due to their low sensitivity and/or high noise. Large format infrared photon counting arrays with ranging capability would provide a valuable tool to many… more
Abstract:Long range, RF space communications do not meet anymore the bandwidth requirements or power constraints of future NASA missions. Optical communications offer the potential to dramatically increase the link bandwidth and decrease the emitter power. High-bandwidth, long-range optical communications… more
Abstract:The unique requirements of the high-voltage capacitive load DC/DC converter for the Navy's non-explosive based acoustic source provide an exciting opportunity for applying innovative design concepts not commonly encountered in commercial power supply product design. The objective of this SBIR… more
Abstract:To meet the ever-increasing power demand of today's spacecraft systems, an integrated power electronics system capable of interfacing, and simultaneously controlling, three power ports will be designed and demonstrated in Phase I of the proposed project. This new proposed power electronic… more
Abstract:DESCRIPTION (provided by applicant): This is an SBIR Phase II proposal directed at the continued development of a diagnostic for the early detection of age-related macular degeneration (AMD). It relies on a functional test of dark adaptation kinetics (the
transition from being light-adapted to… more
Abstract:DESCRIPTION (provided by applicant): This STTR Phase I proposal is directed at the development of a topical treatment for mild psoriasis. It is based on the recent discovery of a cell signaling module important for the regulation of keratinocyte proliferat
ion and differentiation. This signaling… more
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