Abstract:New technology is needed for nondestructive evaluation (NDE) of defects in aluminum structures on ships. Fatigue cracks at weldments where defects may be hidden under paints, rough surfaces and other materials are especially problematic. An NDE technology capable of imaging defects in welds under a… more
Abstract:DESCRIPTION (provided by applicant): DNA microarrays have advanced our understanding of cellular biology by their ability to simultaneously measure mRNA levels for thousands of genes. However, these microarrays are expensive to produce and quality control is a problem due to technical issues… more
Abstract:Due to its excellent properties,CsI:Tl has become the scintillator of choice for a wide variety of applications; however, it has not been widely used in radionuclide imaging in the medical field. The primary reason for this is the presence of a strong afterglow component in its scintillation decay,… more
Abstract:This Small Business Innovation Research Phase I project will develop substrates for enhancing the fluorescence signal from nearby analytes. This will be achieved by utilizing two-dimensional arrays of regularly spaced metallic nanoparticles thereby generating propagating modes of surface plasmons.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I Project involves the development of the Multi-Stage Collector (MSC) for multi-pollutant control. The MSC device is a hybrid electrostatic precipitator (ESP) - barrier filter (BF) device. The Phase I research will incorporate a non-thermal plasma… more
Abstract:This Small Business Innovative Research (SBIR) Phase I project demonstrates the feasibility of producing stearidonic acid from microalgae for human consumption to combat cardiovascular diseases (CVD). The cardiovascular benefits of fish oil enriched in omega-3 polyunsaturated fatty acids (n-3 PUFAs)… more
Abstract:This Small Business Innovative Research (SBIR) Phase I project aims to develop an innovative large-scale photobioreactor for production of natural astaxanthin from Haematococcus strains. The phase I research plan is to construct and evaluate an innovative modular flat-plate photobioreactor for mass… more
Abstract:This Small Business Innovation Research Phase I project will develop technology to automate the creation of survey instrument documentation, to analyze the complexity of survey instruments, and to automate the testing of survey instruments. Software that enables researchers to better visualize,… more
Abstract:The overall objective of this effort is to address a nagging void in the study of Information Age Warfare: there is no coherent set of tools that military analysts can use to visualize, measure, understand and asses networked military systems. While there has been a great deal of effort expended to… more
Abstract:We propose to develop a new fiber optic switch for IRCM applications. The purpose of the phase I program is to demonstrate the feasibility of a high power 1xN (N=2-6) fiber optic switch operating in the mid IR region. By carefully optimizing each individual optical component, the optical switch will… more
Abstract:Composite avionics enclosures with liquid-cooled card guides are predicted to weigh less than current state-of-the-art aluminum enclosure. While there are many successes in developing composite-based Thermal Planes for advanced avionics applications, limited effort has been spent on the enclosure… more
Abstract:The state-of-the-art clutch plate for the lift systems is made of carbon-carbon composites and is challenged to meet future life and frictional requirements. This clutch is very similar in configuration to an aircraft brake, but operates at significantly higher speeds approximately 8500 rpm.… more
Abstract:DESCRIPTION (provided by applicant): Elevated intracranial pressure (ICP) is associated with a number of serious neurological conditions. Its successful management yields improved outcome for patients, yet ICP can only be measured by placing a device within the cranium through a hole in the skull… more
Abstract:DESCRIPTION (provided by applicant): The objective of the proposed research is to develop an ultrasensitive photochemical amplification method for improving the performance of polymerase-chain reaction (PCR)-based detection of human immunodeficiency virus (HIV). A new technology allows one to… more
Abstract:The technical objectives of this SBIR proposal include the design and verification of a frangible composite ILS Glideslope Tower that does not require guy wires (i.e., will maintain existing tolerances and mission performance capabilities). ATSI's technical approach is based upon the high… more
Abstract:DESCRIPTION (provided by applicant): In current medical practice, breast biopsy serves as the gold standard for determining if a breast mass is benign or malignant. Mammography is the main imaging procedure (screening) for detecting suspicious findings with its high sensitivity but its lower… more
Abstract:DESCRIPTION (provided by applicant): The goal of this proposal is the discovery and development of novel drugs to be used in a disease intervention strategy for influenza (flu) infection that comprise short interfering RNAs (siRNAs), the molecules that induce RNA interference. To achieve this goal… more
Abstract:Computational structural mechanics (CSM) is used in energy and other key national industries, and the ever-increasing size of the simulations imposes a pressing neeed for commensurate increases in computational speed, in order to keep costs and computation times in check. This project will… more
Abstract:Design of US Army ground vehicles, especially those that operate in combat environments, faces increasingly challenging requirements. The vehicles should be capable of operating in contrasting rough terrains and must support a wide range of optional equipment and payloads. Component and system… more
Abstract:Manufacturing defects in ceramic composite matrix require 3D fiber architectures to reinforce and toughen both in-plane and out-of-plane directions of CMCs. Modeling 3D material properties and evaluating durability of structures made of 3D composites are of great importance in their application in… more
Abstract:DESCRIPTION (provided by applicant): The ongoing war on terror has created the necessity of a whole new spectrum of systems that are able to detect and inactivate biothreat agents, systems that are inexpensive to produce, robust and stable to allow their use on a massive scale by first responders or… more
Abstract:Microarray technology offers an opportunity for simultaneous monitoring of the behavior of multiple markers within a mammalian cell and ultimately could be used for detection and elucidation of mechanisms of action of different biologically active agents, including those that are considered a threat… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this project is to design and build cameras that can efficiently detect and image isotopes that have gamma rays with energies that are typically beyond those effectively accessible with conventional cameras. There are no nuclear medicine… more
Abstract:An electronically controlled Variable Transmittance Visor (VTV) will permit a pilot to use a Helmet Mounted Display (HMD) system at maximum effectiveness in all lighting conditions without having to add or remove fixed-tint visors. This project will investigate the material and process advancements… more
Abstract:This Small Business Innovation Research Phase I project will establish the feasibility of detecting biological warfare agents (BWAs) using a holographic interferometer. Bio- and Nanotechnologies are enabling this innovation through the preparation of both affinity-based nanoparticles and biosensor… more
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