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Year:2005
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Displaying 476 – 500 of 6801 Awards
Company: Altair Center, Llc. Agency/Program/Year/Phase: DOD / STTR / 2005 / 1
Abstract: ALTAIR Center in cooperation with the University of Rochester proposes to develop the first silicon-based photonic crystal laser diode. The photonic crystal microcavity forms gain region of the laser diode. This enhances the system efficiency. The laser operating either in bandgap edge emitting mode… more
Company: Altair Center, Llc. Agency/Program/Year/Phase: DOD / STTR / 2005 / 2
Abstract: ALTAIR Center in cooperation with the NanoTech Institute at the University of Texas at Dallas proposes to develop a new class of terahertz (THz) lasers generating about 1 mW in the frequency range 0.3-10 THz at room temperature. The proposed concept is based on employing the semiconductor… more
Company: ALTAIRNANO, INC. Agency/Program/Year/Phase: NSF / SBIR / 2005 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project will demonstrate superior power-delivery, rapid-charge, and long cycle-life performance of prototype carbon-coated, nanoparticle-based electrodes for use in inherently safe, moderate-to-large sized lithium ion batteries of various… more
Company: Altea Therapeutics Corporation Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This breakthrough technology, currently… more
Company: Altea Therapeutics Corporation Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) transdermal drug delivery system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This… more
Company: Chromotrax, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): We propose an innovative approach combining two separate, novel techniques to greatly enhance accurate detection of leukemia or lymphoma cells, which can be used ultimately for diagnostics and early detection of minimal residual disease (MRD) in bone marrow,… more
Company: Altex Technologies Corporation Agency/Program/Year/Phase: DOD / STTR / 2005 / 1
Abstract: Altex Technologies, a small business entity, and Pennsylvania State University (PSU), a research organization, have teamed up under this STTR program to develop the innovative Person Portable JP-8 Fueled Fuel Cell-Power Generator (PJF-Gen). The 500-1000 watts PJF-Gen system will be light and… more
Company: Altex Technologies Corporation Agency/Program/Year/Phase: DOD / SBIR / 2005 / 1
Abstract: Low temperature Solid Oxide Fuel Cells (SOFC) operating on JP-8 and other distillate fuels are the ideal power sources for all applications, especially for portable power applications. By operating at lower temperature (400-600 C) these systems have faster response, quicker startup, better longevity… more
Company: X Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The objective of this project is to develop an anti-tissue factor antibody, Sunol-cH36, as a treatment for Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). The association between coagulation and inflammation has been well established and… more
Company: X Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The need to develop novel, cost effective manufacturing processes to produce therapeutic antibodies commercially will continue to be of considerable and growing interest to biopharmaceutical and medical industries. The long-term objectives related to this… more
Company: X Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The long-term objective of this project is to develop small molecule inhibitors of MHC class II activity for the treatment of rheumatoid arthritis (RA). The strong genetic association between specific MHC class II alleles, such as HLA-DR molecules containing the… more
Company: Altoris, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Sex steroids play important roles in a number of cancers including breast, ovarian, endometrial and prostate cancers. In this proposal, we are planning to investigate means to modulate steroid levels in an effort to suppress tumor growth. During the Phase I of… more
Company: Altoris, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The long term goal of this proposal is the development a new class of pharmacological agents that modulate intraocular pressure by altering the levels of cortisol. Our approach consists of the design of inhibitors for an oxidoreductase that acts as a key… more
Company: Altoris, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The long-term goal of this proposal is to develop a new class of pharmacological agents that aid in the management of different aspects of the metabolic syndrome by modulating the levels of cortisol. The compounds could also be of use in the management of… more
Company: Altuda Energy Corporation Agency/Program/Year/Phase: DOE / STTR / 2005 / 1
Abstract: 78000 One way to reduce greenhouse gases is to sequester carbon dioxide. Once sequestered, a bioconversion process can convert carbon dioxide into methane, an environmentally friendly energy source. The process requires an abundance of hydrogen, which is present in the hydrogen-rich coal macerals… more
Company: Amac International, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2005 / 1
Abstract: 79766S05 In order to increase proton energy up to 8 GeV in a driver linear accelerator, particles must be accelerated through various stages and three different power levels (25kW, 100 kW, and 210kw). Unfortunately, no power coupler element for these cavities has ever been produced using U.S.… more
Company: Amac International, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2005 / 1
Abstract: 79784S05 In superconducting cavities used in nuclear physics research, the detection of impurities on to less than 50 micrometer sizes would enable the cavities to reach the highest possible accelerating fields. Currently available equipment can only inspect flat sheets, which allows for defective… more
Company: Amac International, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2005 / 1
Abstract: 79412S05 Superconducting radio frequency (RF) cavities (of which the proposed International Linear Collider (ILC) will need several thousand) require ultra clean vacuum and surface cleanness. A break in a ceramic RF coupler window, with consequent inrushing of air and contaminants, would have… more
Company: Amarillo Biosciences, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Helicobacter pylori (Hp), a gastric bacterial pathogen of humans; infection is the cause of type B gastritis and is also strongly associated with gastric carcinoma (intestinal type) and gastric MALT lymphoma. Combination antimicrobial therapy (triple therapy… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Significant advances have been made in the development of a new generation of molecularly targeted cancer drugs, many of which are only now emerging from the drug development pipeline. Examples of small molecule drugs are imatinib (Gleevec), used to treat CML,… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): There exists an urgent need to develop an effective, non-invasive method of detecting colorectal cancer (CRC), the second leading cause of cancer deaths in the U.S. Such non-invasive testing, if instituted for a large segment of the population, could result in… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Neurofibromatosis (NF) is an autosomal dominant disorder caused by mutations in the NF1 and NF2 genes. Currently, more than 100,000 Americans suffer from NF type 1 (NF1) which has one of the highest prevalence rates for a genetic disease (1/3,500 births). NF1 is… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): This Phase II proposal aims to simplify, expedite, and stabilize the recovery of high quality RNA from tissue samples. In Phase I, we demonstrated the feasibility of a hands-off, closed tube tissue disruption method termed "MELT" (Multi-Enzymatic Liquefaction… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): The overall objective of this proposal is to develop methods for the cost-effective, large-scale synthesis (up to kilograms amounts) of capped, polyadenylated RNA. Several companies are using capped RNA to produce human vaccines against cancers and infectious… more
Company: AMBION DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): The long-term objectives of this proposal are to permit the isolation of RNA from fixed and imbedded tissues for gene expression analysis. The widespread use of tissue fixation and embedding in both clinical and research settings has resulted in the accumulation… more
Displaying 476 – 500 of 6801 Awards
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