Abstract:This Small Business Innovation Research Phase I project aims to examine the feasibility of producing therapeutic proteins in transgenic plants with a biological safety switch that controls the pharmacological activity of the proteins. With the embedded switch, the therapeutics will be inactive… more
Abstract:There is a need for improvement in the performance of thermally and electrically conductive polymeric adhesives used in electronic packaging. In particular, there are few polymeric materi-als that are suitable for replacing eutectic solder bonding in electronic devices used in high-temperature… more
Abstract:The Government is deploying a growing number of radiation detectors at U.S. borders, ports of entry and other key locations, intended to assist in the detection of a potential terrorist`s nuclear explosive device or radiological dispersal device. The most widely deployed radiation detector products… more
Abstract:DESCRIPTION (provided by applicant): The aim is to develop a high resolution, high contrast detector for digital x-ray imaging systems. The target detector would have a Detective Quantum Efficiency much greater than 80%, a limiting resolution of at least 10 lp/mm, ultra-low noise, linear response… more
Abstract:Building on prior success in detector electronics, we propose to design and fabricate a 256 channel readout ASIC for solid state gamma radiation array detectors having a power consumption of less 100 microW/pixel, an event detection throughput of more than 10,000 events/sec, and a dynamic range of… more
Abstract:AI Signal Research, Inc. proposes to develop a Non-Intrusive Vibration Measurement System (NI-VMS) for turbopumps which will provide effective on-board/off-board fault detection diagnostic capabilities without relying on any intrusive installation of once per revolution (1/Rev) tachometer key phasor… more
Abstract:A prototype Next Generation MK III Lightweight HUT/Hatch Assembly will be fabricated and delivered during Phase II. Maximum weight reduction for the Hard Upper Torso - Hatch assembly will be acheived via the innovative material selection and cross sectional redesign investigation Air-Lock conducted… more
Abstract:Air-Lock will deliver a final report based on the follwoing:1. Historical summary of bearing design evolution throughout the life of the EMU Program2. Material research to identify lightweight materials best suited for each beairng.3. Redesign of current EMU bearings to lower bearing profile and… more
Abstract:78026S05 New scintillator materials must be synthesized and evaluated for use in detecting and deterring the proliferation of nuclear weapons. However, there are thousands of possible scintillator materials and it is a challenge to determine which of them will have superior properties. This… more
Abstract:Imaging laser radar is evolving into an important tactical sensor, which may be fielded on UAVs. However, UAV systems range in size from micro systems, which have payload requirements of a few ounces to the mini UAVs with payload requirements of tens of pounds. This provides the designer of UAV… more
Abstract:DESCRIPTION (provided by applicant): Cloning of hot and cold thermal receptors has advanced the understanding of the molecular basis of thermal sensation. Two (2) important remaining questions to be addressed are the identification of additional thermal receptor genes and the elucidation of the… more
Abstract:A China has not permitted the importation of USA seed potatoes in over 19 years and signed a new Potato Protocol in 2003. B We must obtain a Chinese Provincial Variety Evaluation to comply with the current China Seed Law. C We have 10 USA potato varieties under a preliminary evaluation by Chinese… more
Abstract:The United States Coast Guard`s homeland security mission includes providing security for 361 ports and 95,000 miles of US Coastline. This coastline is susceptible to both criminal and terrorist attack. Waterside facilities and critical infrastructure are especially vulnerable to attack from on or… more
Abstract:Acoustic sensor systems are the backbone of both anti-submarine (ASW) and mine-countermeasure (MCM) systems. Inadequate knowledge of the acoustic environment, especially in denied areas, results from a lack of survey equipment, funding, and access to areas of tactical interest. Moreover, the… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will research, prototype, and test a novel system for improving performance and reducing injuries due to improper body mechanics in sports such as baseball, football, and tennis. The innovation of the proposed system is twofold: First,… more
Abstract:Complex and expensive instrumentation is currently required to test the NOAA Weather Radio (NWR) receivers because of their unique characteristics. There is a critical need for a small, portable, dedicated broadcast simulator specifically designed to evaluate NWR system performance. This SBIR Phase… more
Abstract:This Small Business Innovation Research Phase I research project will investigate the feasibility of using a high-speed linear array of micro grating light modulators (GLM) for cost-effective maskless lithography. Current maskless lithography tools are low-throughput instruments designed for the… more
Abstract:75239S Municipal solid waste landfills are the single largest source of anthropogenic methane emissions in the United States, producing 7 million tons, or 34% of the nation's total methane pollution. According to the Intergovernmental Panel on Climate Control¿s third assessment report, methane… more
Abstract:DESCRIPTION (provided by applicant): This proposal aims at the development of hydrophilic, hydrolytically stable wall coatings for plastic microchips made from poly (methyl methacrylate) (PMMA) and/or polycarbonate (PC). In analytical chemistry of the last decade, miniaturization of analytical… more
Abstract:High performance energetic materials are based on inorganic thermite mixtures such as MoO3/Al or organic compounds such as RDX. Future developments in explosives are dependent on the fabrication of nanoscale materials and composite mixtures that display higher energy release rates. The ability to… more
Abstract:This Small Business Technology Transfer Phase I project provides for the manufactureof improved boron nitride (BN) filler materials for electronic thermal management applications. Novel Atomic Layer Deposition (ALD) nanocoating is used to selectively functionalize edges only or edges/basal planes… more
Abstract:This Small Business Technology Transfer Phase I project will develop technology for the manufacture of low cost miniaturized multi-layer capacitors (MLCs). A titania (TiO2) thin film will be deposited on 60 to 150 nanometer nickel (Ni) particles to protect the ultrafine Ni particles from slow… more
Abstract:DESCRIPTION (provided by applicant): In this Phase I SBIR project Alderon Biosciences Inc. (ABI) proposes to demonstrate the feasibility of using electrochemical reverse transcriptase (eRT) assays for determinations of HIV viral load in clinical samples. Success will set the stage for Phase II… more
Abstract:DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. To meet this need, Alderon Biosciences Inc. (ABI) proposes to develop innovative, low-cost… more
Abstract:DESCRIPTION (provided by applicant): Murine models of cancer now have an essential role in formulating modern concepts of carcinogenesis and metastasis, and provide us with a realistic means of developing and evaluating new diagnostic and therapeutic techniques. Moreover, transgenic and knock-out… more
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