Abstract:DESCRIPTION (provided by applicant):
The purpose of this proposal is to develop a protein assay technology that will parallel the newly developing oligonucleotide microarray techniques. We will develop a peptide system capable of performing high throughput real time measurements in parallel on a… more
Abstract:DESCRIPTION (provided by applicant): We propose the development of a microfluidic real-time PCR microarray technology that is far beyond the capability of today's hybridization-based DNA microarrays. This new technology will enable a broad range of research and diagnostic applications that require… more
Abstract:A crucial component of the Joint Battlespace Infosphere (JBI) is a collection of cooperating fuselets, simple programs or scripts that effect small transformations on data, thus transforming data into knowledge. Based on successful Phase I accomplishments, ATC-NY, in collaboration with Architecture… more
Abstract:Distributed systems, important to civilian and military infrastucture, have steadily become more complex and steadily more difficult to understand, implement, and maintain. Addressing these dangers, a collaboration between ATC-NY and Cornell University will build a mathematically based tool, … more
Abstract:To meet the demand for more "intelligent" applications-in web services, enterprise software, network management, etc.-developers are turning to the AI technique of rule-based programming. But the very things that make rule-based programming attractive-its flexibility, its introduction of complex and… more
Abstract:Testing accounts for a large and growing share of software development costs. Developing tests is labor-intensive; and significant savings would result from tools that could automatically generate tests meeting some given criterion of completeness. ATC-NY proposes to build a set of modules, Tiger,… more
Abstract:Ultra Wideband (UWB) technology provides high-speed, low-power wireless networks with a low probability of detection and interception, and is resistant to jamming. This promising technology lacks support above the physical layer to provide capabilities that the Army requires for intra-vehicle… more
Abstract:The Principle of Least Privilege says that programs should operate with sufficient privilege to get the job done, but no more, in order to minimize the harm that can be done in case of error. The Empirical Privilege Profiling system (EPP) will collect data about privileges actually exercised by… more
Abstract:The Transparent Software Protection Infrastructure (TSPI) is a collection of software modules that enhance software protection during the software development process. TSPI uses wrapper technology to provide a layer between COTS development systems and the file system. It provides security to… more
Abstract:ATC-NY and Bigwood Systems, Inc. will design and build Zebra, an innovative access control system for electric power SCADA systems. Access control decisions will depend on the dynamic state of the electric transmission/distribution system, in addition to conventional inputs such as identity. We will… more
Abstract:The Phase I Empower Math Project (EMP) will result in a technology capable of delivering
authentic, engaging, and relevant mathematics studies and understanding to a 9-12 grade
audience. EMP is the result of fusing two existing complementary computer-based learning
systems, developed by the proposer… more
Abstract:DESCRIPTION (provided by applicant): The development and institution of stem cell and tissue engineering methodologies hold the potential to target many of the most significant cardiovascular diseases and have a dramatic impact on the treatment of one of the leading causes of death in the United… more
Abstract:DESCRIPTION (provided by applicant): The goal of this Phase I proposal is to identify novel regulators of transcription factor NFkappaB. The products of this Phase I discovery program will be targets utilized in a Phase II campaign to develop of small molecule inhibitors as potential new drug… more
Abstract:DESCRIPTION (provided by applicant): The objective of the current proposal is to establish genetic modification of Multipotent Adult Progenitor Cells (MAPCs) with Synthetic Microchromosome vectors (SMCs) as a strategy for application in autologous cell based therapy of Hurler's Syndrome… more
Abstract:DESCRIPTION (provided by applicant): Recent advances in our understanding of DNA repair mechanisms have led to the identification of the DNA repair specific nuclease, Artemis. Mutations in this enzyme do not affect viability, but enhance cellular sensitivity to ionizing radiation through the… more
Abstract:The objective of this project is to create a commercialized version of a Common Parts Catalog (CPC) Information Management System that is practical, highly flexible and cost-effective for small and medium sized (second tier) shipyards. The CPC Information Management System will interface with a… more
Abstract:The objective of this project is to demonstrate with Marinette Marine (a Manitowoc Company) and Bollinger Shipyards, the shipyards of the Lockheed-Martin LCS project team, that their design software of choice, ShipConstructor (from Albacore Research Ltd.) can, through a middleware developed as part… more
Abstract:The objective of this proposal is to build a cost-effective and flexible paint planning and estimating system to enhance the surface coating processes of U.S. shipyards. Utilizing parts and product information from the shipyards product model environment, the proposed paint planning system will… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project will develop a Dynamic Torsional Knee Ankle Foot Orthosis (DTKAFO) for the treatment of Metatarsus Adductus/Varus (MTA), Internal Tibial Torsion (ITT) and Talipes Equinovarus (TEV). The DTKAFO offers an easy-to-use brace that… more
Abstract:Future Department of Defense space-based systems will require long-life, active cryocoolers capable of achieving sub-10 K load temperatures. Currently, the available cryocooler technology at these temperatures is too massive and inefficient. In many cases, reliability is low and vibration high.… more
Abstract:For the future spaceport and storage of liquid hydrogen NASA requires cryocoolers that can provide more than 10W of cooling at 20K. The closed-cycle cooling alternatives currently available for such applications are not well suited to their requirements. In many cases reliability is low and… more
Abstract:Future NASA programs will utilize solid-state devices (e.g., detectors, processors) that require cooling. Thermal management is of critical importance for a variety of solid-state devices. As the size of solid-state devices continues to shrink, device performance and reliability is limited by the… more
Abstract:Future instruments and platforms for NASA's Earth Science Enterprises will require increasingly sophisticated thermal control technology, and cryogenic applications will become increasingly more common. For example, Fourier Transform Spectrometers capable of high-accuracy cloud-profile measurements… more
Abstract:Many future advances in NASAys ability to perform cutting edge space science will require improvements in cryogenic system technology, including the development of light-weight, low vibration, highly-efficient, long-life cryocoolers. One such cooler, currently under development, is the… more
Abstract:Future NASA planetary and astrophysics missions will require various enhancements in multi-stage cryocoolers. These include increased efficiency, reduced vibration and reductions in overall system mass and power consumption. For the small coolers required, pulse tube and Stirling coolers offer the… more
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