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Year:2003
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Displaying 576 – 600 of 7277 Awards
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the… more
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the… more
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the most important respiratory pathogen in infants, especially those born prematurely. It is also an important cause of disease in the elderly and immunosuppressed. There is no vaccine available to protect against RSV and "at… more
Company: APATH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The drug discovery industry is under increasing pressure to rapidly prioritize compound candidates based on their efficacy and specificity. Although traditional chip based gene expression microarrays can provide significant insights, sample format and throughput… more
Company: APD LIFE SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The FDA and blood banking societies recognize that bacterial detection to reveal contamination in stored blood products is a direct approach for reducing the problem of post-transfusion bacterial sepsis, and potentially can allow extension of currently approved… more
Company: APD LIFE SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): The FDA and blood banking societies recognize that bacterial detection to reveal contamination in stored blood products is a direct approach for reducing the problem of post-transfusion bacterial sepsis, and potentially can allow extension of currently approved… more
Company: aPeak Inc. Agency/Program/Year/Phase: DOE / SBIR / 2003 / 1
Abstract: 72725S03-I Scintillating and wavelength shifting fibers have increasingly demonstrated advantages over traditional radiation detection/tracking for high energy physics and nuclear physics experiments. As the number of channels increases, traditional instruments (photomultipliers, CCDs, and… more
Company: APECOR Agency/Program/Year/Phase: DOD / SBIR / 2003 / 2
Abstract: This Small Business Innovation Research Phase II project proposes a solar-based expandable, parallel-connected power system with robust maximum power point tracking (MPPT) capability. As the need for flexible, scalable solar power requirements increases,and in an effort to avoid the redesign of the… more
Company: APERIO TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): This Phase-I SBIR application addresses the increasingly significant challenges faced by pathologists and clinicians in manually inspecting microscope slides. Microscopic inspection suffers from being labor-intensive, subjective, expensive and limited by the… more
Company: APHIOS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by investigator): The terrorist events of September 11th and the recent criminal anthrax exposures have increased awareness of the use of smallpox as a biological weapon. A shortage of the vaccine and the incidence of vaccine-related deaths will preclude protection of everyone… more
Company: APHIOS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Influenza is a common and serious respiratory illness affecting tens of thousands each year and causing 20,000 - 40,000 deaths. This significantly contributes to the loss of manpower hours and revenue each year. Annual vaccine programs are in place to protect… more
Company: APL Sciences, Inc. Agency/Program/Year/Phase: USDA / SBIR / 2003 / 1
Abstract: NON-TECHNICAL SUMMARY: Species identification of catfish is necessary for the detection of inappropriately labeled products. U.S. farmed Channel catfish has ranked fifth among the top consumed fishery products since 1999. Due to its high value and immense popularity the Channel catfish is… more
Company: APL Sciences, Inc. Agency/Program/Year/Phase: USDA / SBIR / 2003 / 1
Abstract: NON-TECHNICAL SUMMARY: Due to its high cost, popularity and demand, Atlantic blue crab meat is susceptible to substitution using less valuable, imported crab species. There are no diagnostic tests available to distinguish pasteurized crab meat samples. The purpose of this project is to develop,… more
Company: APL Sciences, Inc. Agency/Program/Year/Phase: USDA / SBIR / 2003 / 2
Abstract: NON-TECHNICAL SUMMARY: Due to its high cost, popularity and demand, Atlantic blue crab meat is susceptible to substitution using less valuable, imported crab species. There are no diagnostic tests available to distinguish pasteurized crab meat samples. The purpose of this project is to develop,… more
Company: APOGEE BIOTECHNOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: The goal of this project is to identify and characterize novel inhibitors of human N-myristoyltransferase (NMT) that are effective as cancer therapeutic agents. Studies have shown that NMT catalyzes critical steps in the processing of several oncoproteins, and that genetic inhibition of this process… more
Company: APOGEE BIOTECHNOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The long-term goal of this program is to identify and evaluate novel inhibitors of human sphingosine kinase (SK) as anticancer therapeutic agents. We have focused on SK as a innovative molecular target for cancer therapy because of its critical role in… more
Company: APOLLO INSTRUMENTS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2003 / 2
Abstract: We propose to develop a kilowatt fiber laser that is highly efficient at the conversion of electrical power into a diffraction-limited laser beam. The overall goal of this program is to deliver an unprecedented kilowatt-class fiber laser. The laser will becompact in size and light in weight. The… more
Company: APOLLO LIGHT SYSTEMS, INC. Agency/Program/Year/Phase: HHS / STTR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Vitamin D deficiency is now recognized as a significant health problem for middle-aged and older adults. Vitamin D deficiency exacerbates osteoporosis and causes the bone disease, osteomalacia. Vitamin D deficiency increases risk of skeletal fractures. It is well… more
Company: Applied Biomathematics Agency/Program/Year/Phase: NSF / SBIR / 2003 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project aims to develop methods and software that can be used to evaluate or explore the impact of human population and land-use changes on species viability. Changes in human population and land use affect the viability of native species… more
Company: Applied Biomathematics Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): The risk from an environmental contaminant is estimated with a risk equation involving the contaminant's concentration and other factors. Because the overall goal of risk management is to ensure such risks are not intolerably large, we need some way to back… more
Company: Applied Biomathematics Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The risk from an environmental contaminant is estimated with a risk equation involving the contaminant's concentration and other factors. Because the overall goal of risk management is to ensure such risks are not intolerably large, we need some way to back… more
Company: AppliCote Associates Agency/Program/Year/Phase: NASA / SBIR / 2003 / 1
Abstract: Technical AbstractApplicote Associates proposes a 6 month $70K program to establish thefeasibility of controlled laser doping of silicon carbide as an enablingprocess step for the fabrication of advanced microelectronics and sensorsrequiring thermal management, high temperature stability, high power… more
Company: APPLIED BEHAVIORAL RESEARCH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: Bridging the gap between science and practice has been identified as an area of major emphasis for NIDA and NIAAA. Manualized individual Twelve-Step Facilitation has been demonstrated to be effective in well-controlled, randomized clinical trials, but still not widely practiced outside of clinical… more
Company: Applied Biotechnology Institute Agency/Program/Year/Phase: USDA / SBIR / 2003 / 1
Abstract: NON-TECHNICAL SUMMARY: Industrial proteins produced in plants, particularly corn, offer a unique opportunity for industrial scale production of enzymes at competitive prices and yields that will address markets that cannot be addressed today. These corn-produced enzymes open the possibility to… more
Company: Applied Biotechnology Institute Agency/Program/Year/Phase: USDA / SBIR / 2003 / 1
Abstract: NON-TECHNICAL SUMMARY: The production of ethanol from lignocellulosic biomass can utilize large volumes of agricultural residues that are untapped today. Ethanol fuels burn cleanly, thus the use of ethanol for partial replacement of petroleum fuels will have a positive impact on the environment. The… more
Displaying 576 – 600 of 7277 Awards
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