Abstract:Bonded repair is a preferred technique for repairing localized damage in aircraft structures that can provide an efficient method for restoring the ultimate load capability of the structure. However, the effectiveness of a bonded repair depends heavilyupon the integrity of the bonding interface… more
Abstract:Bonded repair is a preferred technique for repairing localized damage in aircraft structures like Apache, Chinook and Comanche that can efficiently restore the ultimate load capability of the structure. However, the effectiveness of the repair depends uponthe integrity of the bonding interface… more
Abstract:DESCRIPTION (provided by applicant): World-wide public health surveys point to an increased global health burden for serious psychiatric disorders, particularly depression. Indeed, by 2020 it is expected that depression may be the second most serious medical condition with respect to global… more
Abstract:DESCRIPTION (provided by applicant): Marine natural products are diverse in chemical structure and have great biological activities, especially anticancer activities. However, developing these compounds into clinical drugs has been hindered by their limited supply. Acera Biosciences, Inc. has… more
Abstract:ACIT will design and demonstrate a remotely addressed crack/flaw detection system for composite materials. It will consist of a passive embedded sensor and a handheld portable detector, operating on the principle of the coupling of the LC tank circuit withthe behavior of a strain sensitive resistor.… more
Abstract:DESCRIPTION (provided by applicant): Spinal cord injury (SCI) inflicts trauma to the cells and tissues of the central nervous system and causes a severe and debilitating condition in the individual. Following SCI, limited regeneration of injured neurons results in permanent disability characterized… more
Abstract:Acoustech plans a two-year effort aimed at evaluating acoustic dyadic sensors for prospective use in directional sonobuoys utilized by the U. S. Navy. The chief sonobuoys targeted in this study are the AN/SSQ-53 DIFAR, AN/SSQ-77 VLAD, and AN/SSQ-62 DICASSunits. The DIFAR and VLAD buoys are passive… more
Abstract:This SBIR Phase II research project strives to develop an Advanced Ultrasonic Beamformer that is unparalleled in its scalability and signal processing features. The ultrasonic beamformer architecture will be unique in its breadth of features. The architecture was developed as the superset of… more
Abstract:DESCRIPTION (provided by applicant): A technique is proposed for the development of an intraoperative, 3-dimensional registration of C-arm fluoroscopic images with spatially-registered ultrasound visualization and implant guidance of radioactive implants and on-line implant assessment during the… more
Abstract:The proposed project will develop prototype software for a Stochastic Neural Network for Missile Reliability Prognostics. A neural network model will be developed to predict missile reliability based on the environmental history of particular missiles.Prediction training will be employed to predict… more
Abstract:This STTR project will develop and validate a robust, scalable computational capability for the simulation of weapon-target interactions of interest to the Army. The proposed algorithm is based on the FLIP (Fluid Implicit Particle) - MPM (Material PointMethod) - MFM (Multiphase Flow Method)… more
Abstract:The proposed project will demonstrate the feasibility of developing a data driven prognostic fault tolerant smart weapon system concept for the Airborne Laser. A real-time prognostic health management (PHM) system will be developed to track the likelihoodof future system or subsystem failures and… more
Abstract:72216S03-I This project will develop and demonstrate a seismic data processing technology that facilitates exploration in complex geologic areas, improves reservoir characterization for both oil and gas, increases the accuracy of estimating petrophysical attributes, and decreases the costs of… more
Abstract:This Phase I project will demonstrate a virtual computer environment that links geographically dispersed computer systems over the Internet to solve large computational problems. Ultimately, the technology will deliver compute power from dedicated sources, over the Internet, on-demand, creating a… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a key technology designed to enhance the definition and characterization of oil reservoirs, by using state-of-the-art 3-D prestack depth imaging technology coupled with advanced rock physics principles to produce… more
Abstract:DESCRIPTION (provided by applicant): Currently, there exist a number of methods for the study of transcription factors and gene-promoter activity. These include reporter gene assays, gel shift assays, and expression-profiling methods such as microarray analysis and SAGE. These methods are well… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is the development of novel methods for the study of the Class II Nuclear Receptors Thyroid hormone receptor (TR), Retinoic Acid Receptor (RAR), and Vitamin D3 Receptor (VDR). Like other members of the nuclear receptor superfamily,… more
Abstract:A shock mitigating suspended seat, which places the Special Forces Operator in an optimal ergonomic position, will be developed for use in the NSW 11M RIB. It will feature a semi-actively controlled shock absorber to optimize the suspension for a broadrange of operator weights and sea states. In… more
Abstract:In the high noise environment of fixed and rotary wing aircraft used for casualty evacuation, a critical need exists to detect normal vs. pathologic heart and breath sounds and discriminate among their components. Evaluations by the Army staff at theU.S. Army Aeromedical Research Laboratory has… more
Abstract:Active Signal Technologies proposes a thoroughly planned systematic development effort to produce a system that will meet the requirements of rugged operational monitoring to provide continuous electrocardiogram (ECG) and ventilation data on activelydeployed personnel. The program starts with a… more
Abstract:DESCRIPTION (provided by applicant): With over 1.5 million persons suffering head injury annually in the U.S., and approximately 50,000 dying from these injuries, a need exists for early direct assessment of brain injury. Currently, injuries must be inferred from Glascow Coma Scores (GCS), low blood… more
Abstract:In Phase I we determined that available ANAM data, while extensive, was inadequate for normative purposes because of wide variations in testing conditions, test battery configuration, and subject demographics. In Phase II, we will complete our survey ofexisting data to define a general purpose ANAM… more
Abstract:Data from original and archival sources will be used to compile normative values for both single and repeated administrations of selected ANAM test batteries. These norms will then be used to develop and evaluate strategies for creating cognitive statusreports (CSRs) for use by clinicians, field… more
Abstract:DESCRIPTION (provided by applicant): Serious wheelchair accidents have risen to almost 37,000 per year. Users of power chairs are three times as likely to have accidents as users of manual chairs! Many people can neither walk nor successfully navigate a wheelchair, e.g., many with MS, quadraplegia,… more
Abstract:DESCRIPTION (provided by applicant):
ActivX Biosciences (ActivX) will develop and validate a novel toxicoproteomics platform to correlate changes in protein activity with compound toxicology. This platform uses fluorescent chemical probes to interrogate catalytically active proteins related by… more
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