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Year:2001
Company: Acorda Therapeutics, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: Spinal Cord Injury (SCI) is a devastating condition for which there is no effective treatment. The cost to society is enormous because most new cases occur in people under the age of 30 and these individuals have a near normal life expectancy. Therefore, the development of a new, effective therapy… more
Company: Acorda Therapeutics, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: The goal of this project is to conduct pre-clinical tests of components
of the extracellular matrix molecule tenascin-C that offer potential
as therapeutics for enhancing nerve fiber regeneration. This may lead to the
development of a treatment for spinal cord injury, a… more
Company: ACOUSTIC IDEAS, INC. Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: Budgetary constraints on defense spending have highlighted the importance ofprograms aimed at extending the service life of aging aircraft. Nondestructiveinspection is a key component of such programs. One important capabilityis the detection of cracking and corrosion around fastener holes. Phased… more
Company: ACROMETRIX CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (Applicant's Abstract): Nucleic acid testing procedures for
genotyping of viral pathogens provide results that are utilized in the
diagnosis and treatment of diseases such as hepatitis and AIDS. Medical
products that directly measure these genetic… more
Company: ACRYMED, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (provided by applicant): Wound infection is the single-most
important complication encountered in the management of chronic non-healing
wounds. More than 10 million US patients per annum, at a cost of greater than
$10 billion, receive treatment for chronic… more
Company: ACRYMED, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 2
Abstract: DESCRIPTION (provided by applicant): Wound infection is the single-most
important complication encountered in the management of chronic non-healing
wounds. More than 10 million US patients per annum, at a cost of greater than
$10 billion, receive treatment for chronic… more
Company: ACRYMED, INC. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (Verbatim from the Applicant's Abstract): More than 15 million
patients in the US alone suffer from recalcitrant non-healing wounds with an
estimated expenditure of greater than $10 billion in treatment costs. The
demographic shift in longevity will mean an… more
Company: ACTA Incorporated Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: The proposed innovation is a new computational and analytical structural acoustic technique for aircraft interior noise prediction. Its innovative quality resides in the unifying theory by which conventional finite element analysis (FEA) and statistical energy analysis (SEA) are related through the… more
Company: ACTA Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: A six-month Phase I project is proposed to demonstrate the feasibility of a hierarchical method for more accurately estimating the material parameters of constitutive models in DYNA3D, thereby enhancing the fidelity of nonlinear finite element models. Thehierarchical approach combines the distinct… more
Company: ACTA Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2001 / 1
Abstract: A 24-month Phase II project is proposed to develop and implement models that capture the fidelity of high fidelity physics-based (HFPB) models in a fast-running format. It is anticipated that such models will be incorporated in certain modules of theModular Effectiveness/Vulnerability Assessment… more
Company: ACTA Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2001 / 2
Abstract: A 24-month Phase II project is proposed to develop and implement models that capture the fidelity of high fidelity physics-based (HFPB) models in a fast-running format. It is anticipated that such models will be incorporated in certain modules of theModular Effectiveness/Vulnerability Assessment… more
Company: Active Control eXperts, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: Vibration reduction will be an important contributor to the success of future earth observing platforms. Unwanted motion in the micrometer to nanometer range must be prevented from interfering with components requiring precise alignment and pointing such as telescopes and interferometers. Active… more
Company: Active Control eXperts, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2001 / 2
Abstract: Active Control eXperts (ACX), Inc. proposes a Phase I research and development effort for the development, conceptual design, and proof-of-concept experiment of a hybrid active/passive sound attenuation system for aircraft interiors. While the attenuation of structural vibration and structure-borne… more
Company: Active Control eXperts, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: Active Control eXperts (ACX), Inc. proposes a Phase I research and development effort for the development, conceptual design, and proof-of-concept experiment of a hybrid active/passive sound attenuation system for aircraft interiors. While the attenuation of structural vibration and structure-borne… more
Company: 3dgeo Development Inc. Agency/Program/Year/Phase: NSF / SBIR / 2001 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project will develop a seismic processing system that enables the delivery of leading-edge seismic services over the Internet and Intranets. Internet-based seismic processing (INSP) enables exploration companies to directly control their… more
Company: 3dgeo Development Inc. Agency/Program/Year/Phase: NSF / SBIR / 2001 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase II project will develop a seismic processing system that enables the delivery of leading-edge seismic services over the Internet and Intranets. Internet-based seismic processing (INSP) enables exploration companies to directly control their… more
Company: Active Motif, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (Applicant's abstract): Peptide nucleic acids (PNAs) have a number
of features that suggest they would be ideal probes for purifying mRNA. In this
revised format we have demonstrated the use of phosphono PNAs (pPNAs) in an RNA
isolation procedure that improves the… more
Company: Active Motif, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (Applicant's abstract): In this application we will discuss the
rationale for the development of a novel method for chemically tagging a
synthetic oligonucleotide to the 5'-end of full-length mRNAs using the cap
structure (7-methyl guanosine triphosphate,… more
Company: Active Motif, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: In this proposal we discuss the development of a technique to amplify the signal generated
when a labeled chimeric oligonucleotide hybridizes to it target sequence. Clearly there is
a huge need for such a technique given the amount of variability that occurs during
triditional amplification… more
Company: Active Motif, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION (provided by applicant): The overall experimental approach of this
proposal is targeted to design an innovative format for arraying proteins.
Instead of using the common glass slide or nitrocellulose membrane to spot
proteins onto, we proposed to use a silica… more
Company: Active Signal Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: DESCRIPTION: (Verbatim from the Applicant's Abstract) Active Signal
Technologies, in partnership with the Brain Attack Team of the University of
Maryland Medical Center, proposes to develop a novel portable, non-invasive
system that will enable rapid identification… more
Company: Active Signal Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 2
Abstract: Active Signal Technologies proposes to further develop its self applied, electrodeless home monitoring device for sleep apnea with the ultimate goal of making clinical diagnosis available to a much larger population of sleep disorder patients than currently possible. Preliminary results from Phase I… more
Company: Active Signal Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2001 / 1
Abstract: Active Signal Technologies proposes to further develop its self applied, electrodeless home monitoring device for sleep apnea with the ultimate goal of making clinical diagnosis available to a much larger population of sleep disorder patients than currently possible. Preliminary results from Phase I… more
Company: Aculight Corporation Agency/Program/Year/Phase: DOD / SBIR / 2001 / 2
Abstract: Present, laser based, countermeasure systems are too large and too expensive for deployment. Aculight will apply its propritary optical mounting techniques to reduce the size and cost of these IR transmitters. Further, Aculight will remove the power,controls and diode laser pumps from the laser… more
Company: Aculight Corporation Agency/Program/Year/Phase: NASA / SBIR / 2001 / 1
Abstract: We propose here to develop a practical multi-species sensor for atmospheric gas concentrations and fluxes. The sensor will be based upon Tunable Diode Laser Absorption Spectroscopy (TDLAS), which is a highly sensitive and selective measurement technique. The practicality of this technique has up to… more
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