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Year:1991
Company: ANATRACE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: GENERALLY, OXYGEN AFFINITY INCREASES AFTER TREATMENT OF HEMOGLOBIN S (HBS) WITH COVALENT ANTISICKLING AGENTS, SUCH AS IMIDOESTER CROSSLINKING REAGENTS. ADDING INOSITOL HEXAPHOSPHATE (IHP) DURING THE CROSSLINKING PROCEDURE WILL LOWER THE AFFINITY, PROTECT THE 2,3-DIPHOSPHOGLYCERATE BINDING SITE AND… more
Company: Amparo Corp.on Agency/Program/Year/Phase: DOE / SBIR / 1991 / 1
Abstract: A NOVEL, NONDESTRUCTIVE, LONGITUDINAL, CHARGED PARTICLE BEAMDIAGNOSTIC TOOL TO MEASURE LONGITUDINAL BEAM PROFILE AND CHARGE DENSITY DISTRIBUTION IS BEING STUDIED. THE CONCEPT IS BASED ON THE EFFECT OF MUTUAL ATTRACTIVE FORCES EXERTED BY THE PARTICLE BEAM ON A COLLINEAR ELECTRON BEAM OF… more
Company: Amparo Corp.on Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: BOTH ATMOSPHERIC AND HIGH-ALTITUDE NUCLEAR EXPLOSIONS WILL PRODUCE MAGNETIC SIGNALS THAT ARE DETECTABLE OVER VERY LARGE DISTANCE. AN UNDERGROUND EXPLOSION WILL ALSO PRODUCE A MAGNETIC SIGNAL, BUT IT IS DETECTABLE AT MUCH SMALLER DISTANCE. THIS IS BECAUSE THE UNDERGROUND FIREBALL IS INERTIALLY TAMPED… more
Company: Amsen Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: TO CREATE A DOPPLER IMAGER OF A TARGET, SUCH AS A SATELLITE, WITH A LASER RADAR, IT IS NECESSARY TO HAVE A LASER CAPABLE OF CREATING A SUITABLE. DOPPLER IMAGE RESOLUTION IS DIRECTLY RELATED TO THE LENGTH OF THE LASER PULSE (THE AMOUNT OF THE TARGET ILLUMINATED IN AN INSTANT OF TIME), AND THE… more
Company: Amtec Engineering Inc Agency/Program/Year/Phase: NASA / SBIR / 1991 / 1
Abstract: SEVERAL AEROSPACE VECHICLES ARE CURRENTLY BEING CONSIDERED THAT HAVE A SIGNIFICANT PORTION OF THEIR FLIGHT PATH IN THE UPPER REACHES OF THE ATMOSPHERE. THE FLOW ABOUT THESE VEHICLES IS IN THE CONTINUUM-TRANSITION REGIME WHERE THE STANDARD EQUATIONS OF CONTINUUM FLOW, THE NAVIER-STOKES EQUATIONS,… more
Company: Amtec Engineering Inc Agency/Program/Year/Phase: NASA / SBIR / 1991 / 1
Abstract: ADVANCED SHORT TAKEOFF/VERTICAL LANDING AIRCRAFT ARE DESIGNED TO USE EXHAUST JETS DIRECTLY TO INCREASE LIFT. BEING ABLE TO MODEL NUMERICALLY THE FLOW FIELDS INVOLVED IN THESE DESIGNS WOULD GREATLY IMPROVE THE DESIGN PROCESS. THIS PROJECT WILL DEVELOP A COST-EFFECTIVE FLOW ANALYSIS TOOL FOR MODELING… more
Company: Amtec Engineering Inc Agency/Program/Year/Phase: NASA / SBIR / 1991 / 1
Abstract: COMPUTATIONAL FLUID DYNAMICS (CFD) METHODS GENERATE VAST AMOUNTS OF NUMERICAL DATA THAT MUST BE DISPLAYED GRAPHICALLYFOR USE. CURRENT GRAPHICAL COMPUTER SOFTWARE PROGRAMS CAN DISPLAY DATA ONLY ON LINES OR ON SURFACES DEFINED IN THE COMPUTATIONAL GRID. CFD SOFTWARE USERS DESIRE TO DISPLAY CFD DATA ON… more
Company: Anesta Corpon Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: WORLDWIDE, IT IS ESTIMATED THAT 4.3 MILLION PEOPLE DIE OF CANCER EACH YEAR AND THAT ROUGHLY 70 PERCENT OF THE TERMINALLY ILL CANCER PATIENTS EXPERIENCE PAIN AS A MAJOR SYMPTOM DURING THE COURSE OF THEIR DISEASE. EVEN THOUGH THE MAJORITY OF THESE PATIENTS RECEIVE OPIOIDS FOR PAIN MANAGEMENT, UP TO 30… more
Company: Anacapa Sciences, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: THIS PROPOSAL DESCRIBES A PLAN AND METHODOLOGY FOR DETERMINING THE TECHNICAL MERIT AND FEASIBILITY OF DEVELOPING AN INTELLIGENT ONBOARD MISSION PLANNING SYSTEM FOR ADVANCED ARMY ROTORCRAFT. ONBOARD MISSION PLANNING, ALTHOUGH EXTREMELY DIFFICULT, IS ALREADY NECESSARY IN SOME ARMY OPERATIONS, AND THE… more
Company: Angstrom Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: PROJECT OBJECTIVES ARE TO IDENTIFY AND MODEL THE INTEGRATED LSA PROCESS TO FACILITATE IMPLEMENTATION OF POLICY AND GUIDANCE FOR THE ACCOMPLISHMENT OF INTEGRATED LOGISTIC SUPPORT OF NAVY SYSTEMS AND EQUIPMENT ACQUISITIONS. OUTCOME OF PROCESS MODELING WILL INCLUDE THE IDENTIFICATION AND PROPOSED… more
Company: ANALATOM, INC. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: THEORETICAL CHEMISTRY TECHNIQUES ARE USED TO PROVIDE FUNDAMENTAL UNDERSTANDING OF THE MOLECULAR REQUIREMENTS FOR ACHIEVING CONDUCTIVE PROPERTIES IN POLYMER SYSTEMS AND IN A LATER STAGE TO ADDRESS THE REQUIREMENTS FOR ACHIEVING NONLINEAR OPTICAL PROPERTIES. IT IS PROPOSED TO DEDUCE THE CONDUCTION… more
Company: ANALIZA, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE PHASE I PROJECT RESULTED IN THE DEVELOPMENT OF SEVERAL TATTOO PIGMENTS THAT WERE EFFECTIVE IN IDENTIFYING B6C3F1 BROWN MICE IN A 3-MONTH STUDY. THESE PIGMENTS DID NOT AFFECT GROWTH OR MORTALITY; HOWEVER, ONE PIGMENT WAS CYTOTOXIC TO IN VITRO MOUSE LYMPHOMA CELLS. THE PHASE II PROJECT WILL… more
Company: Annapolis Research & Dev Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: THIS PROPOSAL WILL DEMONSTRATE (IN 2" TO 4" SIZE), A NOISE REDUCING TRIM THAT CAN BE UTOLIZED IN ROTARY CONTROL/ON-OFF BALL VALVES. THIS VALVE TRIM ADDRESSES NOISE AT THE SOURCE. THE BASIC DESIGN HAS A VARIABLE IMPEDENCE TRIM TO CAUSE A HIGH IMPEDENCE AT LOW ANGLES OF OPENING AND LOW IMPEDENCE (VERY… more
Company: Analysis & Computer Systems I Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: THIS PROPOSAL IDENTIFIES THE MANUAL INPUTS REQUIRED FOR THE AUTOMATIC TERMINAL INITIALIZATION (ATI) COMPUTER AID AND FORMULATES A PLAN TO REPLICATE THIS MANUAL PROCESS IN AN ARTIFICIAL-INTELLIGENCE BASED COMPUTER PROGRAM. IT WILL PROVIDE AUTONOMOUS GENERATION OF A DATA SET REQUIRED TO SUPPORT… more
Company: Anro Engineering, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: IMPULSE RADAR HAS BEEN SHOWN TO BE VERY FLEXIBLE AND COST-EFFECTIVE FOR FIXED AND MOBILE SECURITY SURVEILLANCE. THE FIRST IMPULSE RADAR SECURITY SYSTEM INTRODUCED FOR MILITARY APPLICATIONS IS PORTABLE, LIGHT-WEIGHT, AND HAS A RANGE OF 300 FEET AGAINST A WALKING HUMAN TARGET. THIS CLASS OF SENSOR IS… more
Company: ANSOFT CORP. Agency/Program/Year/Phase: NSF / SBIR / 1991 / 1
Abstract: A NEW CONCEPT IS DESCRIBED IN WHICH AN ALTERNATING MAGNETIC FIELD IS USED TO INDUCE A "SWEEPING" ELECTRIC FIELD WITH ADJUSTABLE "SWEEP ANGLE" AND "FREQUENCY" FOR GEL ELECTROPHORESIS. THE EASILY ADJUSTABLE SWEEP ANGLE AND FREQUENCY ARE KNOWN TO BE KEY FACTORS IN RESOLUTION OF ELECTROPHORESIS SYSTEMS… more
Company: Antech Services Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: DEPLETED URANIUM PENETRATOR REMNANTS MAY BE PRESENT IN THE SOIL AND ULTIMATELY COULD BECOME DISPERSED IN THE AIR OR WATER, CREATING HEALTH HAZARDS. CURRENT TRENDS AND DECONTAMINATION PRACTICES MAY REQUIRE REMOVAL AND DISPOSAL OF VAST AMOUNTS OF SOIL TO ENSURE URANIUM REMOVAL. MOST OF THIS SOIL IS… more
Company: ANTICANCER, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THERE IS AN IMPORTANT NEED IN THE STUDY OF TOXICOLOGY OF TOPICALLY-APPLIED AND ENVIRONMENTAL AGENTS FOR AN IN VITRO SYSTEM TO STUDY THEIR TOXIC EFFECTS ON SKIN. THE IN VITRO SYSTEMS HAVE THE BENEFIT OF ALLOWING STUDY OF A LARGE VARIETY OF SUBSTANCES ON AN INDIVIDUAL SPECIMEN. AN IN VITRO SYSTEM… more
Company: ANTICANCER, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: METASTATIC RATES FROM SUBCUTANEOUS XENOGRAFTS IN NUDE MICE HAVE BEEN LOW POSSIBLY DUE TO SITE OF IMPLANTATION. THE APPROACH IS TO USE ORTHOTOPIC ONPLANATION OF INTACT TISSUE SPECIMENS RATHER THAN CULTURED CELL LINES OR DISSOCIATED TISSUE SPECIMENS. RESULTS HAVE INDICATED A HIGH TAKE RATE (SUCCESS IN… more
Company: Antropix Corpon Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: WE WILL DEVELOP A LASER SYSTEM THAT IS SUITABLE FOR PERFORMING PHOTOTHERMAL INTRASTROMAL KERATOPLASTY TO CORRECT OCULAR REFRACTIVE ERRORS. LASER PARAMETERS (WAVELENGTH, IRRADIANCE, AND IRRADIATION TIME) AND DELIVERY/GEOMETRY PARAMETERS (BEAM PROFILE, SPOT SIZE, PATTERN, AND SLEW RATE) SHALL BE… more
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