Abstract:ABSTRACT: The objective of this STTR Phase II project is to continue the development of a fine scale forecast model capability that will provide a technologically superior, high resolution atmospheric decision tool to accurately predict areas of clear air turbulence in the upper troposphere and… more
Abstract:Our approach for protecting critical program information in US weapons systems from exploitation or reverse-engineering efforts is based on a new sensor technology. Utilizing advances in the field of nanotechnology and the sub-field of plasmonics, our design is miniscule in size and allows for… more
Abstract:The goal of this project is to develop STC101, a biosmilar Herceptin . Trastuzumab is a monoclonal antibody made against the HER2 protein that is overexpressed in 20-25% of patients with breast cancer. Because of high cost associated with prescribing Herceptin , a generic version of this drug would… more
Abstract:DESCRIPTION (provided by applicant): The SHARE Program: Supporting Health, Activities, Resources, and Education is a seven-session early stage intervention for care dyads (the IWD and a family CG) that takes advantage of a time when the IWD can still discuss the diagnosis and plan for the future.… more
Abstract:Goals of 80% clean energy production for the United States by 2035 and 20% of the countrys power being supplied by wind energy by 2030 imply nearly a tenfold increase in wind power production. This means that the need for forecast information will extend to longer projection windows with increasing… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project addresses the need for breakthrough technologies in the production of ultrahigh temperature (UHT) ceramics, including nanograin structures, with improved performance-to-cost ratio. UHT ceramics are often challenging to densify. The… more
Abstract:The energetic material community has a need to produce energetic materials in varying particle sizes and morphologies. Control of particle and morphology allows the formulator to investigate various aspects of processing and performance associated with the energetic material. Unfortunately,… more
Abstract:NALAS proposes to address the challenge for novel fluorine-containing propellant components with a 3-fold approach: 1. Synthesize a fluorinated analog of BTTN as novel fluorinated plasticizer. 2. Prepare fluorinated analogs of hydroxyl-terminated polybutadiene (HTPB). 3. Prepare a novel fluorinated… more
Abstract:During Phase I of this project, NALAS endeavored to conceive a remotely operated trial nitration system that would remove the operator from harm"s way and facilitate the trial nitration process by enhancing data acquisition and enabling the creation of a data library providing guidance on… more
Abstract:ABSTRACT: In this proposal, SK Infrared LLC (SKI), a spin off from the Krishna Infrared Detector (KIND) laboratory at the University of New Mexico, is teaming up with Raytheon Vision System (RVS) to develop a flat top broadband high operating temperature mid wave infrared and long wave infrared… more
Abstract:The objectives of this proposal are to further preclinical development of unique two-photon-activated photodynamic therapy (TPPDT) triads that incorporate a nontoxic porphyrin photosensitizer, a tumor targeting group, and an imaging functionality, providing for noninvasive image-guided treatment of… more
Abstract:Despite concerted efforts on both the part of the food industry and Federal regulators, already in 2011 there have been Salmonella foodborne illnesses in 31 U.S. states. Salmonella is a leading cause of foodborne illness. It is responsible each year for an estimated 1 million illnesses, 19,336… more
Abstract:This is a critical crossroads for the poultry industry with a majority of consumers demanding minimal or chemical free foods and the ever present threat of foodborne illness from Salmonella and Listeria associated with raw and ready-to-eat (RTE) poultry products. As a potential solution, we have… more
Abstract:A growing body of research underscores the need to prepare students socially—as well as academically—to ensure successful transition to middle school and foster subsequent academic success. This project team is developing a prototype of a series of web-based interactive games to help students… more
Abstract:DESCRIPTION (provided by applicant): The prevalence of nutrition-related conditions (overweight/obesity, cancer, diabetes, heart disease, etc.) among Americans is widely documented. During the last twenty years, the frequency of dining out has increased, with Americans currently eating… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project concerns the development of an optical fiber biosensor platform that achieves exceptionally high sensitivity through use of a nanoscale, high refractive index, self-assembled polymer coating on the cladding surface. A rapid, specific,… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost portable retinal camera, the DLP-Cam, in a community-based system for diabetic retinopathy (DR) screening and treatment. Untreated DRhas reached epidemic levels in underserved… more
Abstract:DESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction.… more
Abstract:DESCRIPTION (provided by applicant): In the present STTR we propose to investigate two novel approaches in our exploration of the therapeutic and regenerative potential of cell-based medicine. Furthermore, we will utilize a preclinical animal model of compression syndrome (CS) that mimics the… more
Abstract:For humans and robots to effectively work together, they must share a common understanding of concepts defining the environment and the relationship of those concepts. In this proposal, we present an approach for dynamic interface creation which takes advantage of a robot-centric ontology. We first… more
Abstract:ABSTRACT: When a structure breaks up following a blast event, it allows the blast wave to propagate through a new opening into another airspace; this continuation of the blast wave is called"secondary blast"and may cause damage to elements in the other airspace. Each step in this process… more
Abstract:Applied Science Innovations proposes development of metrology on corrective optics for aerodynamic domes using the improved Interferometric Tomography, building directly on ASI's successful development of a new tool for metrology on conformal aspheric windows, domes and corrector optics. The… more
Abstract:Applied Science Innovations proposes Phase II development of metrology on corrective optics for aerodynamic domes using the improved Interferometric Tomography, building directly on ASI"s successful development of a new tool for metrology on conformal aspheric windows, domes and corrector… more
Abstract:The primary technical objective to be achieved during Phase II is the transition from the developed laboratory prototype, which clearly demonstrated the feasibility and superior outcomes of the approach, to a deployable system consisting of two key elements (the reference station - compression side… more
Abstract:DESCRIPTION (provided by applicant): Cardiotoxicity, as a result of adverse drug effects, is a serious problem that has yet to be effectively screened prior to patient exposure. Cardiac safety is one of the leading causes of compound attrition in the pharmaceutical industry and withdrawal of… more
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