Abstract:The Navy needs a metal cutting system for submarine and aircraft carrier hull disposal. We propose to develop a Hull Cutting Mill (HCM) to meet Navy needs. Our HCM uses a compact high-speed high-power hydraulic milling head to perform slot-milling and achieve a fast lineal speed cutting high-tensile… more
Abstract:ABSTRACT: We propose to develop for the Air Force a high-efficiency Waste Heat Removal System (WHRS) that removes large amounts of waste heat from aircraft with negligible impacts on signature and aerodynamic performance. Our WHRS absorbs heat from aircraft thermal loads, including a Thermal… more
Abstract:This Small Business Innovation Research Phase I project seeks to greatly improve the light output of white-light light-emitting diodes (LEDs) using fluorescent nanoparticles or quantum dots (QDs) made from silicon. The most efficient and economical design for a contemporary white LED is based on a… more
Abstract:DESCRIPTION (provided by applicant): Schistosomiasis is a major neglected tropical disease of public health concern to a billion people with 200 million currently infected and 779 million at risk to acquire the infection, the majority of these in Africa.The disease has a high impact on affected… more
Abstract:DESCRIPTION (provided by applicant): Funding of this application will move a new combination cancer therapy for leukemia and lymphomas towards human clinical trials. Monoclonal antibodies, mAbs have emerged as a rapidly growing class of oncology therapeutics. Despite their success in certain… more
Abstract:Develop an inexpensive, easy to use, aerosolized delivery system of a combination of anti-tubercular drugs that could be used for the treatment of multi-drug resistant tuberculosis (MDR TB ). PUBLIC HEALTH RELEVANCE
Abstract:DESCRIPTION (provided by applicant): Based on the poor performance of fourth grade students on national and international tests of mathematics, it is evident students in the early grades are not adequately prepared in mathematics. Several researchers havedemonstrated that students who complete… more
Abstract:DESCRIPTION (provided by applicant): Acute respiratory infections (ARIs) represent a major cause of morbidity and mortality in the world1. About 20% of all deaths in children younger than 5 years of age are due to ARIs, with among those 90% attributed to pneumonia. This translates into approximately… more
Abstract:For soldiers in the field, there are limited opportunities for normal hygiene. Showers/bathing facilities are limited, as is the ability to launder uniforms, underwear and bedding. A lack of clean water can make even basic hygiene difficult-- in addition to the obvious problem of unsanitary drinking… more
Abstract:Proposed is the development of a manufacturing technology that will increase feasible large optics design options and significantly reduce the manufacturing time, cost and risk involved in manufacturing large optic components. Specifically addressed are cutting and light weighting of glass and… more
Abstract:Analyze a tethered VTOL system capable of carrying and maintaining the required communications relay components to at least 500 feet AGL for up to four days continuously. The VTOL and comms relay package receive power delivered using laser power from the surface vehicle over fiber optic cable and… more
Abstract:DESCRIPTION (provided by applicant): The objective of this project is to further develop an immunotherapeutic strategy for HIV-associated malignancy based on the role of HPV in the pathogenesis and perform the pre-clinical experiments with a new drug whichallow us to enter clinical trials to test… more
Abstract:The DOE is evaluating deep borehole disposal of nuclear waste, where waste packages are emplaced in the lower sections of holes drilled 3 to 5 km deep in crystalline rock. A variety of plug and backfill materials are placed in the boreholes above the waste packages as structural and sealing members… more
Abstract:This is a proposal for the development of a geothermal-solar thermal pilot plant to be built on the Oregon Institute of Technology campus, a solar thermal array supplementing the geothermal power facilities. The recent award to ENEL for a geothermal-solar PV hybrid system had come to my attention… more
Abstract:Observing solid-liquid interfaces with high resolution is important for comprehension of physical, chemical and biological interactions between material and fluid. A more detailed knowledge of these interactions can substantially improve our understanding of the processes that occur during … more
Abstract:This SBIR Phase I project will develop a microfluidic in-situ TEM specimen holder with accurate environmental parameter monitoring capabilities; The inability to dynamically image materials at atomic resolutions in changing liquid environments is a significant impediment to the advancement of… more
Abstract:The inability to dynamically image solid-state materials at atomic resolutions and perform spectroscopy at the same time in changing liquid and gas environments is a significant impediment to the advance of multiple areas of science. Recently Hummingbird Scientific has developed commercially viable… more
Abstract:ABSTRACT: This proposal addresses the need for solutions that enable higher levels of spacecraft autonomy to reliably maintain operational capabilities. Random hardware faults and hostile threats necessitate autonomous systems capable of responding quickly and effectively to these threats and… more
Abstract:Converting biomass to biofuels and bio-based chemicals using efficient, sustainable, environmentally benign, and economical production methods has proven to be economically challenging. Biomass generally needs to be broken down and separated into its various components, however, biomass is highly… more
Abstract:DESCRIPTION (provided by applicant): Three novel uncharged silver microbicides have been shown to be effective against a wide variety of pathogens have been shown to spontaneously form amorphous hydrogels when combined with glutathione will be formulated into two different ointment formulations and… more
Abstract:DESCRIPTION (provided by applicant): The goal of this project is to develop a dual-mode PET/x-ray mammography scanner (PET/X) to improve the way in which breast cancer therapies are matched to patients by providing early evaluation of therapy efficacy through 'window' studies on an… more
Abstract:Incorporating hypervisor-based software virtualization into spacecraft architectures offers the capability to integrate payload software in a plug-and-play fashion, enabling more flexible and reconfigurable platforms. The hypervisor allows the payload software to be implemented in an abstracted,… more
Abstract:DESCRIPTION: While the detection and characterization of intact proteins and protein complexes is an exciting prospect, current proteomics measurement capabilities are lacking in a variety of crucial aspects such as measurement throughput, detection of low abundance proteins, and substantial issues… more
Abstract:Traditional chemical sedatives for the processing of farm-raised fish are considered animal drugs that are subject to specific regulations and usage constraints (as well as chemical-bath disposal concerns). As an alternative, we propose to evaluate the use of mild, non-lethal electrosedation… more
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