Abstract:Sample return missions, by nature, require high levels of spacecraft autonomy. Developments in hardware avionics have led to more capable real-time onboard computing platforms, which allow for the implementation of more sophisticated algorithms. A real-time convex optimizer named COARSE (Convex… more
Abstract:If the energy resolution of electron energy loss spectroscopy (EELS) carried out in a scanning transmission electron microscope (STEM), with an atom-sized electron probe, could be improved to 10 meV or better, a new way of studying materials at the atomic scale, by recording and analyzing their… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop a high--?]throughput --?] surface acoustic wave nebulization (HTP--?]SAWN) ion source for mass spectrometry (MS). The SAWN ion source developed during phase I resulted in a device that has competitive performance between… more
Abstract:This Small Business Innovation Research Phase I project will focus on the development of ceramic nanosheets with structurally different sides (sticky/slick), which will be used to form a self-generating tribological coating for improved lubrication. This coating will be automatically created during… more
Abstract:DESCRIPTION (provided by applicant): Magnetic beads have gained increasing use as a convenient separation technique for many forms of cell, nucleic acid and protein isolations and analyses. In particular, the manufacturers of clinical immunoassays utilizemagnetic beads both as a solid support for… more
Abstract:The innovation evaluates the feasibility of developing a tablet-based suite of applications that allow students to interrogate relationships between molecular sequences, molecular structures, and their biological functions. One of the most difficult concepts for students to understand is why certain… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project is focused on the reuse of waste glass to generate high-value replacements for traditional masonry products. Masonry manufacturers cannot meet the construction industry's needs with their status quo product and are therefore losing… more
Abstract:The current method for monitoring hexavalent chromium in groundwater at environmental legacy sites is labor intensive, costly and does not allow for continuous in situ monitoring. The research project is developing an affordable, sensitive, durable and low-maintenance in situ sensor capable of… more
Abstract:The Navy needs a metal cutting system for submarine and aircraft carrier hull disposal. We propose to develop a Hull Cutting Mill (HCM) to meet Navy needs. Our HCM uses a compact high-speed high-power hydraulic milling head to perform slot-milling and achieve a fast lineal speed cutting high-tensile… more
Abstract:ABSTRACT: We propose to develop for the Air Force a high-efficiency Waste Heat Removal System (WHRS) that removes large amounts of waste heat from aircraft with negligible impacts on signature and aerodynamic performance. Our WHRS absorbs heat from aircraft thermal loads, including a Thermal… more
Abstract:This Small Business Innovation Research Phase I project seeks to greatly improve the light output of white-light light-emitting diodes (LEDs) using fluorescent nanoparticles or quantum dots (QDs) made from silicon. The most efficient and economical design for a contemporary white LED is based on a… more
Abstract:DESCRIPTION (provided by applicant): Schistosomiasis is a major neglected tropical disease of public health concern to a billion people with 200 million currently infected and 779 million at risk to acquire the infection, the majority of these in Africa.The disease has a high impact on affected… more
Abstract:DESCRIPTION (provided by applicant): Funding of this application will move a new combination cancer therapy for leukemia and lymphomas towards human clinical trials. Monoclonal antibodies, mAbs have emerged as a rapidly growing class of oncology therapeutics. Despite their success in certain… more
Abstract:Develop an inexpensive, easy to use, aerosolized delivery system of a combination of anti-tubercular drugs that could be used for the treatment of multi-drug resistant tuberculosis (MDR TB ). PUBLIC HEALTH RELEVANCE
Abstract:DESCRIPTION (provided by applicant): Based on the poor performance of fourth grade students on national and international tests of mathematics, it is evident students in the early grades are not adequately prepared in mathematics. Several researchers havedemonstrated that students who complete… more
Abstract:DESCRIPTION (provided by applicant): Acute respiratory infections (ARIs) represent a major cause of morbidity and mortality in the world1. About 20% of all deaths in children younger than 5 years of age are due to ARIs, with among those 90% attributed to pneumonia. This translates into approximately… more
Abstract:For soldiers in the field, there are limited opportunities for normal hygiene. Showers/bathing facilities are limited, as is the ability to launder uniforms, underwear and bedding. A lack of clean water can make even basic hygiene difficult-- in addition to the obvious problem of unsanitary drinking… more
Abstract:Proposed is the development of a manufacturing technology that will increase feasible large optics design options and significantly reduce the manufacturing time, cost and risk involved in manufacturing large optic components. Specifically addressed are cutting and light weighting of glass and… more
Abstract:Analyze a tethered VTOL system capable of carrying and maintaining the required communications relay components to at least 500 feet AGL for up to four days continuously. The VTOL and comms relay package receive power delivered using laser power from the surface vehicle over fiber optic cable and… more
Abstract:DESCRIPTION (provided by applicant): The objective of this project is to further develop an immunotherapeutic strategy for HIV-associated malignancy based on the role of HPV in the pathogenesis and perform the pre-clinical experiments with a new drug whichallow us to enter clinical trials to test… more
Abstract:The DOE is evaluating deep borehole disposal of nuclear waste, where waste packages are emplaced in the lower sections of holes drilled 3 to 5 km deep in crystalline rock. A variety of plug and backfill materials are placed in the boreholes above the waste packages as structural and sealing members… more
Abstract:This is a proposal for the development of a geothermal-solar thermal pilot plant to be built on the Oregon Institute of Technology campus, a solar thermal array supplementing the geothermal power facilities. The recent award to ENEL for a geothermal-solar PV hybrid system had come to my attention… more
Abstract:Observing solid-liquid interfaces with high resolution is important for comprehension of physical, chemical and biological interactions between material and fluid. A more detailed knowledge of these interactions can substantially improve our understanding of the processes that occur during … more
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