Abstract:DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) affects approximately 1.3 million adults in the United States and up to 1.5% of the population worldwide. In its progressive form the disease has debilitating effects including painful inflammation and destruction of the joints. This… more
Abstract:DESCRIPTION (provided by applicant): Age-Related Macular Degeneration is the most common cause of legal blindness in people over 60, affecting an estimated 1.6 million patients. Additionally, over 400,000 diabetic Americans are diagnosed each year with vision-threatening retinal edema and/or… more
Abstract:DESCRIPTION (provided by applicant): With 33 million people living with HIV/AIDS (including 1.2 million in the US), and 1.8 million AIDS-related deaths annually, HIV/AIDS remains a formidable global epidemic (UNAIDS, CDC). Modern HIV therapy combines drugsfrom different classes to form cocktail … more
Abstract:With the current state of world events, the threat of buried explosives used against military vehicles is more pronounced than ever before. The introduction of the MRAP and MTVR vehicles have helped mitigate this threat to a degree, but military personnel continue to suffer from both death and… more
Abstract:A multiscale modeling approach is proposed for the development and implementation of physics-based EOS and constitutive models within a multimaterials continuum modeling framework. Accurate EOS and rate-dependent constitutive (flow, yield stress, damage) models for plate glass, PMMA and segmented… more
Abstract:This Small Business Innovation Research (SBIR) Phase I will focus on development of novel biopolymers obtained by covalently attaching peptide side chains to hyaluronic acid (HA) backbone polymer chains through carefully controlled chemistry. The resulting material can be used for soft tissue… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop an 840 nm spectral domain optical coherence tomography (OCT) system for intravascular imaging applications. The system will be designed to provide images equal to or better than what is currently clinically available… more
Abstract:Thermal Management Technologies proposes to develop concept designs for a scalable two-phase liquid-vapor immersion cooling system and perform a subscale proof of concept demonstration of the technology. Direct immersion cooling is capable of providing thermal management of individual cells whether… more
Abstract:ABSTRACT: Conductive Composites has developed lightweight materials that provide high levels of conductivity and electromagnetic (EM) shielding for composite and advanced polymer materials systems. Conductive materials include metal coated carbon fibers and nonwovens, along with nickel nanostrands.… more
Abstract:ABSTRACT: Traditional shielding enclosures are fabricated from heavy metallic materials. Polymer and composite systems have been used extensively in enclosures for due to their significant weight and manufacturing advantages, but have not been able to provide adequate levels of electromagnetic… more
Abstract:ABSTRACT: A method of fabricating highly conductive and shielding electrical conduit and associated fittings is proposed. The technology will be based upon creating conductive composite tubes and fittings. Such composites have proven their ability to shield as well as their aluminum counterparts… more
Abstract:The innovation in this project is the application of machine intelligence technology to help entrepreneurs quickly connect to the specific resources and services that will help them on their road to success. Entrepreneurs are a key source of growth and economic development in the United States, but… more
Abstract:ABSTRACT: Silicon Technologies, Inc. (STI) proposes to extend the results of a DARPA sponsored contract # W31P4Q-11-C-0046,"Design Tools For Highly Regular Circuit Geometries"to develop a set of design tools and analog cells specifically for use in automating the design of Rad Hard analog… more
Abstract:ABSTRACT: This effort seeks to identify an effective paint remover that does not contain Hazardous Air Pollutants (HAPs) and does not interfere with the metal removal process at the Hill Air Force Base Industrial Waste Water Treatment Plan (IWTP) while also meeting mil-spec requirements for… more
Abstract:The Navy seeks to develop new, innovative motor/generator technologies that can effectively operate at speeds up to 1,000 kRPM at power densities of 40 kW/kg (excluding heat exchanger) with an overall system efficiency of 95% or better. Such a motor/generator will have a wide range of applications,… more
Abstract:ABSTRACT: Over half of spacecraft system anomalies attributed to interactions with the natural space environment including - electron upsets, damage to components, power system debilities, and complete satellite failures - are attributed to spacecraft charging. While measurements of electron… more
Abstract:This SBIR Phase I project will investigate the possibility of using a network of low-cost, battery-powered radio frequency (RF) transceivers to detect,
localize and track the movements of people illegally trying to enter the US borders through wooded areas. The system uses radio tomography (RT), i.e… more
Abstract:The innovation of this SBIR Phase II project is the development and commercialization of a low-cost through-building surveillance product for police and SWAT teams that locates and tracks people across an entire building using a network of wireless sensors deployed around the outside of the building… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a revolutionary new sensor for aging-in-place and assisted living which uses a network of radio frequency (RF) transceivers as a sensor in a home to track a person?s location and detect falls. The sensor is contact-free, i.e… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project creates a drug-screening platform for discovery of new antiparasitic drugs. Resistance to current drug treatments is on the rise. New antiparasitic drugs under development are mostly focused on neurotransmission targets, yet a new target… more
Abstract:The innovation combines mobile technologies becoming more widely used in schools, an evidence-based beginning reading program with a long history of R & D and widespread use in many settings, ongoing student progress monitoring and assessment with results and instructional recommendations… more
Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project seeks to demonstrate the feasibility of a novel device for rehabilitation in the home environment, by using wireless instrumentation and smartphone technology forfeedback to amputees about their real-time… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will advance the technology research and development necessary to bring wireless instrumentation and smartphone technology used for feedback to lower-limb amputees about their real-time performance, for rehabilitation in situ. The… more
Abstract:DESCRIPTION (provided by applicant): Meningitis and encephalitis are inflammatory, often infectious, processes of the central nervous system that can result in significant morbidity and mortality. Prompt, appropriate therapy is crucial, but determining theinfectious etiology can be difficult and… more
Abstract:DESCRIPTION (provided by applicant): Microscopic analysis of tissue mounted on glass slides is commonly used to study cancer, non-neoplastic entities such as heart disease and diabetes, and normal cell function. Researchers utilize micro and macro tissue dissection techniques in order to recover… more
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