Abstract:SYSTEMS & PROCESSES ENGINEERING CORPORATION (SPEC) HAS DEVELOPED TWO ALTERNATIVE DESIGNS THAT MEET OR EXCEED THE FUNCTIONAL AND TIMING REQUIREMENTS OF THE DIGITAL MODULATOR. THE FIRST IMPLEMENTATION IS CENTERED AROUND A HIGH PERFORMANCE 1.0 UM CMOS APPLICATION SPECIFIC INTEGRATED CIRCUIT (ASIC),… more
Abstract:THE USE OF FIBER OPTIC NETWORKS IN DATA COMMUNICATIONS HAS RAPIDLY INCREASED IN RECENT YEARS. ADVANCED COMMUNICATION NETWORKS TECHNOLOGIES ARE NOW USED IN A WIDE RANGE OF IMPLEMENTATIONS, FROM LOCAL AREA NETWORKS FOR PERSONAL COMPUTERS AND WORKSTATIONS TO PARALLEL PROCESSING NETWORKS FOR… more
Abstract:THE ARMY WILL ULTIMATELY EMPLOY TACTIAL IMAGERY/INFORMATION PROCESSING SYSTEM TO ASSIST COMMANDERS BY INTEGRATING THE BATTLEFIELD SITUATION WITH CHANGING TERRAIN AND ENVIRONMENTAL CONDITIONS. TERRAIN REASONING IS A MAJOR FACTOR INVOLVING SENSOR LOCATIONS, MOBILITY, ROUTE LOCATIONS, CHOKE POINTS,… more
Abstract:The objective of agile manufacturing is to increase competitiveness of the US manufacturing base, while addressing DoD priorities, with a combined goal of improving US global competitiveness and national security. To achieve this objective, significant changes in technology and infrastructure must… more
Abstract:The Defense Mapping Agency (DMA) is the primary provider of terrain data to the military services. Other agencies, such as the US Army Engineering Topographical Laboratory, provide terrain data products as well. DMA currently provides Digital Terrain Elevation Data (DTED) and Interim Terrain Data… more
Abstract:THE OBJECTIVE OF THIS PROJECT IS THE DEVELOPMENT OF A 0.2T "DESKTOP" MAGNETIC RESONANCE IMAGING SYSTEM (MRI) FOR HUMAN LIMBS OR SMALL ANIMALS AND MATERIALS. THE DESIGN IS BASED ON A PERMANENT MAGNET, THUS REQUIRING NO EXTERNAL POWER OR CRYOGENIC MAINTENANCE. BECAUSE OF THE MINIMAL FRINGE FIELD OF… more
Abstract:THIS PROJECT WILL IDENTIFY AND SPECIFY ENGINEERING PARAMETERS NECESSARY TO MANUFACTURE NON-METALLIC ELECTRICAL CONNECTORS FOR UNDERWATER SUBMARINE AND SURFACE SHIP SONAR USE. MORE SPECIFICALLY, THIS PROJECT WILL IDENTIFY EQUIPMENT, MATERIALS AND PROCESSES NECESSARY TO ENABLE NAVAL SUPPORT FACILITIES… more
Abstract:A METHOD IS PROPOSED FOR ESTIMATING REMAINING LIFE OF TEFLON COMPOSITE CHEMICAL/BIOLOGICAL (C/B) SUIT AND ENCLOSURE MATERIALS. THE TECHNIQUE IS BASED UPON THE RELATIONSHIP BETWEEN C/B MATERIAL PERMEABILITY RATE AND SURFACE FRACTURE DENSITY OF FATIGUED MATERIAL. DETECTION OF REMAINING LIFE IS MADE… more
Abstract:Reliability and lifetime performance data for environemntal control systems (ECS) is limited. Real-time tests require 5-15 years, and results often apply only to obsolete technology. Accelerated life testing (ALT) is a means by which reliability data may be obtained quickly and at a reasonable cost.… more
Abstract:THE PRINCIPAL TECHNICAL OBJECTIVE OF THIS PROPOSED SBIR PHASE I STUDY WILL BE TO EXAMINE FLIGHT CONTROL SENSOR AND ACTUATOR INTERFACE REQUIREMENTS AND DETERMINE APPLICABILITY OF DSP TECHNOLOGIES TOWARDS CREATING COMMON I/O MODULES TO REPLACE THE VARIOUS INTERFACES. A SMALL, LIGHT WEIGHT, HIGH… more
Abstract:We will develop a novel class of therapeutics based on Triple-Helix Forming Oligonucleotides (TFOs). Attachment of lipophilic groups to anti-cancer and anti- HSV-2 TFOs will be examined to enhance their cellular efficacy. Specifically, cholesteryl modified TFOs that are designed to bind to the… more
Abstract:Triple helix formation between duplex DNA and oligonucleotides has been observed for over twenty years for synthetic polymers and more recently for genomic DNA. Triplex formation prevents the association of proteins with DNA including transcription factors and RNA polymerase. Triple helix formation… more
Abstract:The aim is to test the feasibility of using triple helix (triplex)-forming oligonucleotides as antiviral agents against human cytomegalovirus. Oligonucleotides have long been known to be capable of binding to duplex DNA to form triple helix complexes. Advances in triplex technology now allows the… more
Abstract:Speech disorders affect over 22 million Americans. Many of these individuals suffer from physical or mental handicaps which prevent the more common speech substitutes of sign language or conventional text-to- speech devices. The device, which is extremely flexible and economical, can reproduce words… more
Abstract:An important aspect in the design of aircraft structure and aeropropulsion components made of high temperature composite materials is damage tolerance and life prediction. Many components contain joints between co posites and metals. There is a need to develop methods for predicting life of such… more
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