Abstract:XRD Inc. will deliver a feasibility study and work plan to produce engines operating on heavy fuel that meets the objectives of Program Solicitation entitled "Small Engines designed for High Efficiency, High Power Density and Quiet Operations". The goal is to have power density greater than 1 hp… more
Abstract:DESCRIPTION (provided by applicant): There is a growing body of evidence that implicates the protein kinase Pim-1 as a major driver of prostate cancer progression, and perhaps response to chemotherapy. Pim-1 is overexpressed in early prostate intraepitheli
al neoplasia and metastatic prostate cancer… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project will address the problem of a multifunctional wide band-gap aluminum gallium nitride single crystal substrate that will enable low-defect,… more
Abstract:This Small Business Innovative Research Phase I project is to develop a commercial growth process for single crystals of KBe2BO3F2 (KBBF) using hydrothermal techniques. KBBF shows exceptional promise as a deep UV non-linear optical material (NLO). NLOs are vital for the development of solid-state… more
Abstract:DESCRIPTION (provided by applicant): Acid ceramidase (AC) has been implicated as a novel target for cancer therapy because of its pivotal role in regulating interconversion of three key bioactive lipids; ceramide (Cer), sphingosine (Sph) and Sphingosine-1-
Phosphate (S1P). It is well known that Cer… more
Abstract:DESCRIPTION (provided by applicant): Long term preservation is crucial as an enabling technology for regenerative medicine products that contain living cells. However, while cryopreservation works well for most cells, some cells are more sensitive and hard
to cryopreserve by freezing. Plus, the… more
Abstract:DESCRIPTION (provided by applicant): The long term goal is the development of better, longer hypothermic storage conditions, using novel insect antifreeze proteins, for liver transplants than is currently possible in clinical practice. The use of hypotherm
ia as the principal means to suppress… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project will develop a gas sensor technology that is both highly sensitive and selective, with a rapidity and accuracy not yet seen in commercially available technologies. This will develop an integrated high performance, low cost, and… more
Abstract:DESCRIPTION (provided by applicant): For over three decades, High-Resolution (HR) Nuclear Magnetic Resonance (NMR) has been a leading analytical technique for structure and function elucidation of molecules of all types, large and small, in homogeneous sys
tems. More recently, Magic Angle Spinning… more
Abstract:Advanced Core Technologies brings three advanced competencies together to support a successful research effort required to identify, foster, and deploy technologies promising reliability enhancing materials and manufacturing innovations. Self-learning search methods, sophisticated information… more
Abstract:The goal of this SBIR Phase II project is to test develop high-strength, low-cost fibers for protective clothing and equipment, shelters and airdrop equipment using commodity olefin polymer materials in a unique fiber production process.
Abstract:Development of a software tool capable of predicting crack growth in structures with complex geometries for accurate structural life predictions and residual strength assessment is proposed. The custom crack growth simulation tool, CRACK3D, will be used as the basic code for further development and… more
Abstract:This Small Business Innovation research Phase I project is to develop flexible, elastic, superhydrophobic surfaces with a technology that physically transforms surfaces by molding microstructures into base polymers, ceramics or metals on a large scale. Uniquely the surfaces may be highly elastic and… more
Abstract:There are often major economic and logistical challenges in getting woody biomass out of the forest or off the farm in a manner, which justifies the costs of harvesting and transportation. Raw cellulosic biomass, woody or otherwise, is moist and bulky, which limits its cost-effective transport to… more
Abstract:Electrical lighting consumes ~22% of the electricity in the U.S., which amounts to more than a third of total energy consumption. With the increasing effectiveness of light emitting diodes (LEDs), the long-term forecast is for the eventual replacement of most traditional lights, both incandescent… more
Abstract:This Small Business Innovation Research Phase I project is aimed at the development of a new consolidated bioprocess to generate hydrogen from inexpensive cellulosic biomass in a single bioelectrochemical reactor. Demand for hydrogen is increasing but a renewable, inexpensive supply does not exist.… more
Abstract:Traditional diode end pumped single mode fiber laser designs are limited in terms laser power pumping and energy extraction. Double clad large mode area fibers are easier to scale up and typically utilize fiber delivered diode pumping at various laser gain length intervals in order to overcome… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will result in the commercialization of high power, large area, deep UV LEDs based on a novel vertically conducting geometry that is arbitrarily scalable. AlInGaN based deep UV-B LEDs (Ã½Ã½ = 300 - 340 nm) have recently been… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase II project will result in the development of a novel semiconductor growth technique to produce low dislocation density III-nitride AlInGaN substrate… more
Abstract:The goal of the Phase I program is to demonstrate the feasibility of our technical approach to grow AlInN lattice Matched Barrier HEMTs on low defect Bulk and quasi-bulk III-Nitride Substrates (GaN). This will be accomplished using our pulsed MOCVD growth technique to deposit AlInN films at a… more
Abstract:The goal of the Phase I program is to demonstrate the feasibility of a high-voltage, high-temperature insulating gate AlInN-GaN/i-SiC enhancement-mode HEMT to serve as the basic building block of a power converter/inverter. Our technical approach is to use lattice matched AlInN-GaN epilayers in… more
Abstract:DESCRIPTION (provided by applicant): Since early development of polymethyl methacrylate bone cement (PMMA-BC), there have been many efforts to develop alternative compositions to circumvent some of its clinical shortcomings, which include (1) monomer cytot oxicity; (3) inability to form strong… more
Abstract:DESCRIPTION (provided by applicant): Bioswellable Absorbable Monofilament Sutures Abstract Phase I study was intended and did demonstrate the feasibility of applying a new concept in macromolecular chain design to develop novel, synthetic, bioswellable, ab
sorbable, compliant, coated and uncoated… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research (SBIR) Phase II project aims to commercialize and expand the application of piezopolymer nanocomposite technology. Piezoelectric materials are an alternative… more
Abstract:Develop economical industrial-scale process for production of bulk gamma radiation detectors based on composite material(s) that have characteristics comparable to large single-crystal detectors. DESCRIPTION: The current generations of moderate- and high-resolution detectors for gamma radiation… more
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