Abstract:DESCRIPTION (provided by applicant): We have identified a novel Type IIb prodrug of riluzole, FC-311, which has the potential to revolutionize therapy for the treatment of the devastating condition of metastatic melanoma acting via a novel glutamatergic mechanism of action, and also be useful to… more
Abstract:Valuable time is spent by astronauts performing simple, mundane, or ergonomically taxing tasks. Therefore, one center of focus for NASA is to have robots increasingly perform these tasks to give the crew more time flexibility. Robots are also employed with tasks that are too dangerous for humans or… more
Abstract:Hook and loop closures in Army uniforms have been identified as the critical sources of leaks in protective clothing/equipment, which limits the overall protective capability of the ensemble. New closure systems capable of providing both the shear and peel strengths demonstrated by hook and loop… more
Abstract:KCF proposes to build a general wireless hearing protection device validation system with miniature, wireless in real ear microphones. The microphones will be battery-free to enable the reduction in size necessary to fit in the canal for testing with any hearing protection device. KCF has… more
Abstract:KCF in partnership with Penn State will evaluate and demonstrate a new generation of intrinsically safe robotic actuators built up from micro-actuator module units. The technical approach is based on state-of-the art prosthetic development where the human-mechanism interface is the primary focus. … more
Abstract:This proposal addresses the opportunity to develop an optimized power and data bus for aircraft rotor loads monitoring by offering an innovative solution that delivers high power density energy harvesting and reliable delivery of large volumes of data from a rotating frame to a fixed frame. The… more
Abstract:The embedded rotor load monitoring system developed under this SBIR project principally consists of Smart Rod Ends and a wireless base station. The Smart Rod Ends are conventional push rod ends that have an energy harvester powered wireless sensor system built into the shank of the rod end. The base… more
Abstract:Kion Defense Technologies, Inc. (KDT) has teamed with multiple CMC producers and an engine OEM to develop and demonstrate the effectiveness of a new, integrated matrix system for SiC-based composites for use at 1300oC (2400oF). Based on feasibility demonstration during the Phase I effort, KDT will… more
Abstract:The proposed Phase 2.5 effort will extend the Phase 2 results to airborne data collected at operational altitudes consistent with the current ASW mission profile. The proposed effort will also be extended to include airborne data collected at altitudes above the current ASW mission profile in an… more
Abstract:Per the topic description, naval airborne sensor systems are utilizing or are planning to utilize varying degrees of automation in the prosecution of their missions as part of future naval capabilities. The automation must handle very dense maritime surface picture conditions that can exceed 1,000+… more
Abstract:Detection, tracking and identification of targets, and subsequent prosecution is very challenging in dynamic environments. Traditional methodologies rely on an operator to analyze all the available information to identify what is actionable, and subsequently modify asset tasking. The operator… more
Abstract:In support of the Missile Defense Agencys Interceptor Missile Program, LithChem Energy (LCE) proposes its MDA Phase II Advanced Power Storage System for Interceptors. LCEs Interceptor Missile Lithium Reserve Battery Program and the successful completion of its MDA SBIR Phase I, resulted in the… more
Abstract:Among the factors that inhibit the use of composite materials in both general aviation aircraft and DoD platforms are the high cost of engineering and the cost of certification. Unless manufacturers can control risk when introducing new materials and pro
Abstract:ABSTRACT: Development and use of new composite materials is imperative for continued advancement of airframe and engine systems. In order to facilitate the accelerated insertion of new composite materials, there is a need for an improved analysis methodology that allows designers to reduce the… more
Abstract:The Navy is developing high speed projectiles for a variety of missions including ship defense, surface fire support, and prompt global strike. Inertial loads and high muzzle velocities impose severe operational conditions on the nosetips and suggest they should be made from refractory metals. While… more
Abstract:It is critical to the safe use of ceramic matrix composite components that information on the fracture toughness of these materials be available, in order to allow an assessment of the likelihood for crack growth. Although Military Standards and American Society for Testing and Materials both serve… more
Abstract:This Small Business Innovation Research Phase I Project focuses on improving lithium-air battery system, one of the most promising electrochemical power sources for energy storage application due to its highest theoretical energy density. The major technical issue which has been gradually unveiled… more
Abstract:DESCRIPTION: Tracing neuronal connections with lipophilic carbocyanine dyes has revolutionized neuroanatomical tract tracing and is an essential feature to understand development of brain connections in both control and mutant mice in particular since multiple colors of dyes can be used. More… more
Abstract:Piasecki Aircraft proposes to meet the challenge of delivering a biological or chemical sample maintained at less than -20 deg Celcius over a range of up to 1000 miles with a precision landing with a portable unmanned aerial system capable of a vertical takeoff, cruise flight range typical of a… more
Abstract:Overrunning modes will be modeled with all the spring elements in a non-CF induced field in order to analytically determine normal forces applied. Transitions, fits, tapers, outer case thickness/wall will be varied to minimize stress and wear surfaces. The specific outcome of Phase I is to use the… more
Abstract:This Small Business Innovation Research Phase I project will develop the ?Grip-Act-Reposition (GAR) Miniaturized Stable Working Platform for Minimally Invasive Procedures Inside Active Organs.? Working within or on moving organs ? like the heart or lungs ? is extremely challenging during minimally… more
Abstract:DESCRIPTION (provided by applicant): The Institute of Medicine (IOM) strongly recommends that all breast cancer patients who are ending active treatment have a survivorship plan. Such a plan should assist patients in moving back to their primary care physician (PCP), provide advice for reducing… more
Abstract:DESCRIPTION (provided by applicant): Management of Type 1 diabetes requires vigilant monitoring by patients who often encounter numerous barriers that can impede proper management. Barriers can include educational, psychosocial, and support issues. PolarisHealth Directions, a small business, and… more
Abstract:We propose to build a comprehensive system architecture which will provide a mechanism for researchers/educators/trainers, to extend their methods and designs from the confines of the research lab environment to the wide-scale and global applied use in the field or at home. We will expand our Phase… more
Abstract:This project will achieve an unobtrusive, wearable sensor array to collect environmental, physiological, and subjective measures associated with physical and cognitive fatigue. The proposed innovation, called the Warfighter Fatigue Data Acquisition System (WFDAS), will be an unobtrusive, modular… more
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