Abstract:The innovation is a new approach to structuring, collecting and using historical geospatial data that will make it possible to rapidly assign a geographic location for text descriptions appearing in historic documents. Geospatial location is a critical element of most documents, and historical… more
Abstract:This Small Business Innovation Research Phase I project is directed towards the development of a non-ionic thickening agent for personal care products, which does not contain poly(ethylene glycol) (PEG). Reports have stated that commercially available PEG contains small levels of undesirable side… more
Abstract:This Small Business Innovation Research Phase I project will develop the ?Grip-Act-Reposition (GAR) Miniaturized Stable Working Platform for Minimally Invasive Procedures Inside Active Organs.? Working within or on moving organs ? like the heart or lungs ? is extremely challenging during minimally… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop Micro-Electro-Mechanical Systems (MEMS) based acoustic emission (AE) sensors for structural health monitoring. AE is a well-established nondestructive testing technique commonly used to monitor for active fatigue cracks in… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop advanced single ion gel electrolytes and related low cost manufacturing process for high power rechargeable lithium ion batteries (LIBs) with enhanced safety. Current LIB electrolytes consist of liquid organic solvents and… more
Abstract:Intellectual Merit This Small Business Innovation Research Phase I project takes a novel approach to produce improved maize cultivars for bioenergy applications. Lignin in cellulosic biomass creates a barrier that limits conversion of cellulose into biofuels. In the proposed approach, the lignin in… more
Abstract:The innovation is an agent-based, data-driven guiding technology that will augment the human facility to evaluate task performance by overcoming human limitations to recall complex processes that require high expertise. The cloud-based, mobile technology will assist teams of varying expertise and… more
Abstract:This Small Business Innovation Research Phase 1 project aims to develop a device to reliably and safely close laparoscopic port sites. Laparoscopy is becoming the gold standard for all abdominal procedures. Laparoscopy requires small incisions to be made in the abdominal wall to allow access to the… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes a new expression platform in Escherichia coli applicable to both drug discovery and biopharmaceutical manufacturing. It solves and leverages recombinant protein misfolding in E. coli. Small molecular weight compounds are used in… more
Abstract:The proposed innovation is a heterogeneous multi-robot team developed as a platform for effective subsurface planetary exploration. State-of-art robotic exploration is based on single-robot systems with human controllers augmented by limited automation. This system requires near-constant… more
Abstract:DESCRIPTION (provided by applicant): StemSynergy Therapeutics Inc. (SSTI) is a biopharmaceutical company focused on the discovery, development, and commercialization of drugs that target pathways fundamental to stem cells and cancer stem cells. The WorldHealth Organization estimates that over 12… more
Abstract:DESCRIPTION (provided by applicant): Despite significant advancements in modern medicine with regards to surgery, radiation therapy and imaging of tumors, the survival rate for patients with non-small-cell lung carcinoma (NSCLC) remain almost identical to20 years ago. Current therapies targeting the… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project investigates the feasibility of employing high?resolution, colorized, 3D models of food produce captured with structured light technology to identify (ID) and sort produce by quality. The feasibility of accomplishing this within the… more
Abstract:A novel yet mature technique will be used to assimilate coherent-source multistatic ASW data obtained from drifting acoustic sources and receivers. We will demonstrate the technique's ability to correctly estimate the locations of drifting buoys from acoustic data only even when the buoys may… more
Abstract:This Small Business Innovation Research Phase-II project develops advanced technology capabilities for constructing and deploying client-adapted automated language translation systems within commercial settings that are used by globalizing enterprises and the language service provider companies… more
Abstract:DESCRIPTION (provided by applicant): This Phase I SBIR will develop ICPCheck, the first long term implantable, non-invasively readable intracranial pressure (ICP) monitor for hydrocephalus patients. This device will result in improved clinical management of hydrocephalus by providing a rapid and… more
Abstract:Zeigler Bros., Inc. (ZBI) has teamed with Harrisvaccines, Inc. (HV) to develop a new aquafeed manufacturing platform for the practical application of underutilized feed additives. These include enzymes, immune-stimulating compounds and biologics that require specialized protection to ensure they… more
Abstract:In this proposal Zeomedix proposes to develop a dressing for infected trauma wounds based on its zeolite encapsulating nitric oxide (NO) technology. Nitric oxide has been shown to enhance the wound healing process as well as act as a powerful antibacterial agent. However, delivery of nitric oxide… more
Abstract:DESCRIPTION (provided by applicant): In the US, about 36,000 deaths occur each year due to influenza and its associated diseases, and 85% of these deaths are in the elderly population. Immunization with flu vaccine is considered the best way to prevent seasonal epidemics and pandemics of influenza.… more
Abstract:Phishing fools end-users into disclosing sensitive information or downloading malware. Commercially available solutions have shown limited success in stopping these attacks. We aim to refine and commercialize novel anti-phishing email and web filtering techniques that overcome these limitations.… more
Abstract:NASA Glenn is examining small fission reactors for future space transportation and surface power applications. The reactors would have an 8 to 15 year design life that could be available for a 2020 launch to support future NASA science missions. Both 1 kWe thermoelectric and 3 kWe Stirling systems… more
Abstract:This project aims to increase the reliability of radio frequency (RF) devices used in accelerator facilities by reducing/eliminating corrosion and erosion produced from the high purity de-ionized water cooling systems. Although metal interconnects are required for electrical and thermal … more
Abstract:This Small Business Innovation Research project proposes to develop a first-of-its-kind hybrid solar-coal gasification technology. The current direct heating gasification technology has two shortcomings: (1) greenhouse gases, resulted from the coal combustion, diluting the syngas product, and… more
Abstract:Silicon carbide (SiC) based devices are currently under investigation for their improved efficiency and high thermal stability. Compared to silicon, SiC has an exceptionally high thermal conductivity and also exhibits better mechanical properties. However, limited research has been performed on SiC… more
Abstract:The proposed SBIR Phase I program will develop an innovative fuel flexible reformer for a portable Solid Oxide Fuel Cell (SOFC) power generation system used in the battlefields. The fuel reformer is non-catalytic and can operate with different fuels including methanol, propane, and JP fuels,… more
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