Abstract:Due to their vast diversity and as-yet uncultivated status, detecting, characterizing and quantifying microorganisms in natural settings are of grand challenge, and understanding the mechanistic linkages between microbial diversity and ecosystem functioning and their feedback responses to human… more
Abstract:The interactions among different microbial populations in a community play critical roles in determining ecosystem functioning but very little is known about the network interactions in a microbial community due to the lack of appropriate experimental data and computational analytic tools.… more
Abstract:DESCRIPTION (provided by applicant): This is an application to test the efficacy of a new approach to cognitive training that is focused on higher level processes such as reasoning and inference. The proposal concerns content of interest to mature adults
. The product that will be developed out of… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project develops a unique and transformative ramp load hard disk drive actuator that provides significant improvements over existing ramp load technology by increasing performance and reducing costs. A ramp is used to park the read/write heads… more
Abstract:This project optimizes haptic system design parameters and more thoroughly evaluates the impact of a vibratory haptic system for prosthetics. Objectives include: (1) building a hardware and software test bed for non-invasive voluntary control of a prosthetic hand with vibratory haptic feedback,… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop a tumor-specific delivery technology based on the use of superparamagnetic nanoparticles as vehicles for the delivery of paclitaxel. The magnetic vectoring drug delivery platform uses external shaped magnetic field… more
Abstract:The ability of humans to make complex decisions is one of the most interesting aspects of human intelligence, especially when judgemental, ambiguous, absense, or erratic knowledge is concerned. This project focuses on the development of a methodology to classify multi-attribute alternatives into… more
Abstract:The Engineering Decision Support Framework (EDSF) will provide an engineer a SEAM based process lifecycle to implement detailed analysis of problem reports, assistance requests, requirements and other issues issues encountered. The engineer will be guided through the creation of criteria,… more
Abstract:The development of micro air vehicles (MAVs) will provide a military capability that has never before been fully realized. Technology developments in areas such as vehicle morphing and energy harvesting will enable greater mission capabilities in terms of intelligence, surveillance and… more
Abstract:As a result of a successful SBIR Phase I effort, Design Intelligence Incorporated, LLC (DII) analyzed and demonstrated the feasibility of innovative perching micro air vehicle (MAV) design concepts using multi-modal energy harvesting techniques. The proposed SBIR Phase II effort will develop an… more
Abstract:DESCRIPTION (provided by applicant): The primary objective of this proposal is to develop and commercialize a safe and more effective therapy for the treatment of Crohn's Disease, an inflammatory bowel disease. Crohn's Disease is a chronic inflammatory dis
order of the gastrointestinal tract that… more
Abstract:The InAs/InGaSb Strained Layer Superlattice (SLS) system is developing rapidly and is now finally poised to seriously challenge HgCdTe as the dominant technology for mid- and long-wave detection. SLS structures have a number of practical and theoretical advantages over HgCdTe materials, including… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop device structures for infrared sensor applications using lead chalcogenides. This system has reduced cooling requirements over other high performance infrared materials (such as HgCdTe) resulting from their reduced Auger… more
Abstract:3-C Cattle Feeder, in collaboration with the New Product Development Center [NPDC] at OSU will develop enhanced prototypes to be tested in the field. The doors to the feeder will be controlled by an RFID reader which actuates a motor allowing the feeder doors to open. For safety, the doors are… more
Abstract:As the Air Force (AF) begins the progression of applying systems engineering from the top-level definition of the system architecture down to a granular level of design it is very important to also realize the changes that will be taking place through Technology Insertion initiatives. Continuous… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer (STTR) Phase I project proposes to research and develop technology for the manufacture of a self-regenerating catalyst with an increased efficacy over commercial… more
Abstract:This Phase I SBIR research addresses two important and related needs regarding management of the national herd during an animal disease outbreak. First, is the need to facilitate keeping the national animal tracking databases (ATDs) as complete, accurate, and up-to-date as possible. The second is… more
Abstract:DESCRIPTION (provided by applicant): Diabetic retinopathy is a common complication of diabetes mellitus and a leading cause of severe vision loss and blindness around the world. The current interventions for DR, laser photocoagulation and vitrectomy, imped
e visual loss but do not improve vision for… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is to examine the efficacy of CLT-005 in reducing ocular inflammation and that occurs during endophthalmitis. Endophthalmitis occurs following the introduction of foreign pathogens into th
e eye. In addition to pathogenic virulence,… more
Abstract:Design Intelligence Incorporated, LLC (DII) proposes an integrated design approach for an innovative perching micro air vehicle (MAV) using energy harvesting. The proposed design concepts will build upon DIIs proprietary energy harvesting technology and hardware and will include innovative… more
Abstract:This SBIR Phase I research proposal will develop intelligent sensors for structural state sensing. It will demonstrate the feasibility of a successful intelligent structural state sensor concept. The advantage of this approach is that, unlike traditional sensors, this technology does not require… more
Abstract:In this Phase I SBIR program, RK Composites, Inc. (RKCI) will develop condition-based self healing systems for multifunctional composite materials. Our technology enables damage mitigation by pre-damage repair, inclusion of condition based monitoring, extensive and tailorable multifunctionality, and… more
Abstract:DESCRIPTION (provided by applicant): Bladder cancer kills approximately 13,000 Americans per year. At least half of these deaths are preventable with no improvements in screening because they occur in people who were initially diagnosed with superficial bl
adder cancer. The problem is that bladder… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase I research project seeks to develop a new technique for enhancing fluorescence-based detection of explosives in order to help counter the threat posed by… more
Abstract:DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. P-selectin mediates the first step i
n the recruitment of white blood cells to… more
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