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Displaying 6126 – 6150 of 6531 Awards
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: A RECENT STUDY HAS REPORTED ELEVATED LEVELS OF P60(C-SRC) PROTEIN-TYROSINE KINASE SPECIFIC ACTIVITY IN 100% OF HUMAN COLON CARCINOMA TUMOR TISSUES AND CELL LINES EXAMINED (1). FOUR MECHANISMS COULD ACCOUNT FOR THIS ACTIVATION: I) A POINT MUTATION AT SEVERAL SITES IN THE AMINO TERMINAL HALF OF THE… more
Company: ONCOGENE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Photographic Sciences Corp. Agency/Program/Year/Phase: NSF / SBIR / 1988 / 2
Abstract: THIS PROPOSAL PRESENTS A RESEARCH PLAN FOR THE MEASUREMENT OF SURFACE DEFECTS ON EITHER HARD DISK MEDIA OR HARD DISK SUBSTRATES. THESE DEFECTS CAN EFFECT THE PERFORMANCE OF A COMPUTER DISK AS THE HEAD TRACKS OVER THE SURFACE. THE PROPOSED RESEARCH PROGRAM IS TO MEASURE SURFACE DEFECTS ON COMPUTER… more
Company: Plasma Physics Corp Agency/Program/Year/Phase: DOE / SBIR / 1988 / 1
Abstract: HYDROGENATED AMORPHOUS SILICON (A-SI:H) IS A REVOLUTIONARY NEW SEMICONDUCTING MATERIAL THAT CAN BE DEPOSITED OVER LARGE AREAS AT RELATIVELY LOW COST, AND IS PARTICULARLY SUITED FOR APPLICATIONS SUCH AS LARGE-VOLUME PHOTODETECTORS IN HIGH ENERGY PHYSICS ACCELERATOR PROJECTS. PEREZ-MENDEZ AND OTHERS… more
Company: Praxis Biologics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: VACCINATION IS THE MOST COST-EFFECTIVE MEANS OF PREVENTING RESPIRATORY SYNCYTIAL VIRUS (RSV) DISEASE. A FEASIBLE APPROACH TO A SAFE RSV VACCINE IS TO MAKE A SUBUNIT OF THE VIRUS, AND THE BEST CANDIDATES ARE THE ATTACHMENT GLYCOPROTEIN (GP90) AND/OR THE FUSION GLYCOPROTEIN (GP70). THE FUSION (F)… more
Company: Praxis Biologics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: LIVE ATTENUATED SALMONELLA STRAINS ARE BEING INVESTIGATED ASVECTORS FOR THE DELIVERY OF FOREIGN ANTIGENS TO STIMULATE A PROTECTIVE IMMUNE RESPONSE AGAINST VARIOUS BACTERIAL, VIRAL,AND PROTOZOAN DISEASES. THESE ORAL VACCINES CURRENTLY UNDERDEVELOPMENT RELY ON EXPRESSION OF FOREIGN ANTIGENS FROM… more
Company: Praxis Biologics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: DIARRHEA IS A MAJOR CAUSE OF MORBIDITY AND MORTALITY IN DEVELOPING COUNTRIES, ESPECIALLY IN INFANTS AND YOUNG CHILDREN. ENTEROTOXIGENIC E. COLI (ETEC) CAUSE A SIGNIFICANT PROPORTION OF THIS DISEASE, AS WELL AS EPISODES OF ACUTE DIARRHEA EXPERIENCED BY TRAVELERS TO LESS DEVELOPEDCOUNTRIES. ALL ETEC… more
Company: Praxis Biologics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: PERTUSSIS TOXIN (PT) IS AN IMPORTANT IMMUNOGEN FOR DEVELOPMENT OF IMMUNITY TO PERTUSSIS, AND CHEMICALLY INACTIVATED PT IS A MAJOR COMPONENT OF ACELLULAR PERTUSSIS VACCINES BEING TESTED IN THE CLINIC. A PROBLEM OF CHEMICAL INACTIVATION IS PRESERVATION OF THE TOXIN'S IMMUNOGENIC PROPERTIES, WHILE… more
Company: Praxis Biologics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE LONG TERM OBJECTIVE OF THIS RESEARCH IS TO GENERATE BACTERIAL CAPSULAR POLYSACCHARIDE-PEPTIDE CONJUGATE VACCINESTHAT WILL PROTECT INFANTS, WHO UNLIKE OLDER CHILDREN AND ADULTS, CAN NOT PRODUCE ANTIBODIES TO POLYSACCHARIDE ANTIGENS. CONJUGATE VACCINES THAT ARE UNDER DEVELOPMENT IN DIFFERENT… more
Company: Praxis Biologics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: PROSPECTIVE COMPUTER ANALYSTS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 2
Abstract: THIS PROPOSAL DESCRIBES AN APPROACH FOR THE DEVELOPMENT OF AN EXPERT SYSTEM TO ASSIST IN MINIMIZING THE QUANTITY OF UUT FAULT INSERTIONS DURING VERIFICATION AND VALIDATION OF TEST PROGRAM SETS. THE PROJECT OBJECTIVES ARE: EVALUATE AND CATALOGUE RULES APPLICABLE TO THE SELECTION OF LRU AND SRU FAULTS… more
Company: PROSPECTIVE COMPUTER ANALYSTS, INC. Agency/Program/Year/Phase: NASA / SBIR / 1988 / 1
Abstract: N/A
Company: Scidmore & Shean Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: PHASE I STUDY OF THE FEASIBILITY OF DEVELOPING A ZOOM LENS AS DESCRIBED IN SBIR TOPIC N88-213 IS PROPOSED. THE OBJECTIVE OF THIS STUDY IS TO INVESTIGATE ALTERNATIVE CONFIGURATIONS TO FIND THE ONE MOST EFFECTIVE IN MINIMIZING COST, SIZE, AND WEIGHT WHILE OFFERING APPROPRIATE OPTICAL CHARACTERISTICS… more
Company: Scientific Associates, Inc. Agency/Program/Year/Phase: DOE / SBIR / 1988 / 2
Abstract: THE PERCUSSIVE JET IS PROPOSED AS A MORE RAPID AND ENERGY EFFICIENT MEANS OF CUTTING REINFORCED CONCRETE AND STEEL THAN LASERS, ABRASIVE BLASTING, OR ABRASIVE JETTING. THE IMPACT CHARACTERISTICS OF PERCUSSIVE JETS (INITIAL IMPACTS, TENSILE FAILURE, AND PERSISTENCE) ALLOW TARGETS TO BE CUT IN WAYS… more
Company: Scientific Associates, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Scs Telecom, Inc. Agency/Program/Year/Phase: NSF / SBIR / 1988 / 1
Abstract: EXISTING DIGITAL RADIO SYSTEMS USE CONTINUOUS PHASE, FREQUENCY MODULATION TECHNIQUES WITH COHERENT DETECTION. THESE SYSTEMS MUST TRADE SPECTRAL EFFICIENCY FOR LOW BIT ERROR RATE AND IN CERTAIN APPLICATIONS SUCH AS SATELLITE AND MOBILE RADIO ARE SUBJECT TO DEGRADATION DUE TO FADING AND DOPPLER SHIFTS… more
Company: Scs Telecom, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: N/A
Company: SENSIS CORP. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: IN ORDER TO DETERMINE THE FAR-FIELD PROPERTIES OF AN ADAPTIVE ARRAY ANTENNA SEVERAL NEAR-FIELD MEASUREMENT TECHNIQUES TOGETHER WITH AN ANALYTICAL MAPPING OR EXTRAPOLATION ARE PROPOSED AND ANALYZED WITH RESPECT TO ACCURACY AND ANECHOIC CHAMBER IMPLEMENTATION LOGISTICS. STEADY STATE PERFORMANCE… more
Company: Smartcard International Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE OBJECTIVE IS TO ADAPT SMART CARDS AS AIDS FOR INDIVIDUALS IN ADHERING TO THERAPEUTIC MEDICAL REGIMENS. THESE MICROELECTRONIC DEVICES HAVE A TMS SERIES MICROPROCESSOR WITH 64K BITS OF EEPROM (REPROGRAMMABLE), A TOUCH SENSITIVE KEYPAD, AND AN LC DISPLAY. AN INTERNAL BATTERY SUPPLIES POWER THAT… more
Company: SPECTRACOM CORP. Agency/Program/Year/Phase: DOE / SBIR / 1988 / 2
Abstract: TO ACHIEVE THE PREDICTED HIGH POWER CONVERSION EFFICIENCIES OF MULTIJUNCTION AMORPHOUS SILICON SOLAR CELLS (A:SI), EFFICIENT USE OF ALL INCOMING SOLAR RADIATION IS NECESSARY. MULTIJUNCTION SOLAR CELL DEVICES ARE EFFICIENT COLLECTORS OFINCIDENT LIGHT, IN THEORY, BECAUSE LIGHT WITH ENERGY LESS THAN… more
Company: Sps Software Products & Servic Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: N/A
Company: Sts Duotex Inc. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: IN 1984 AN NIH CONSENSUS CONFERENCE RECOMMENDED COMMUNITY BASED CHOLESTEROL SCREENING PROGRAMS TO EVALUATE HYPERCHOLESTEROLEMIA IN THE CONTEXT OF ITS ASSOCIATION WITH INCREASED HEART ATTACKS. THERE IS A DEVELOPING LITERATURE THAT THE APOLIPOPROTEINS A-1 AND B ARE BETTER MEASURES OF RISK THAN HDL AND… more
Company: Susquehanna Resources And Agency/Program/Year/Phase: DOD / SBIR / 1988 / 2
Abstract: TO DETECT AND IDENTIFY AIRPLANS AND GROUND TACTICL TARGETS WITH IMAGE DATA, TOW COMPLEMENTARY ANAYSES ARE REQUIRED (1) CONTOUR EXTRACTION, AND (2) SHAPE/TARGET RECOGNITION. UNTIL VERY RECENTLY, RESEARCH EMPHASIS HAS BEEN PLACED ON SHPE RECOGNITION BASED ON SEGMENTATIONS FROM ODELS AND/OR SIMPLE… more
Company: Susquehanna Resources And Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: THIS SBIR PROPOSAL, "INTELLIGENT ALGORITHMS FOR SMART MUNITION SEEKERS," HAS TWO MAJOR OBJECTIVES: (1) TO DETERMINE THE HIT-RATE AND FALSE-ALARM RATE OF THE SR&E SEGMENTOR AND TARGET EXTRACTOR USING A COMPREHENSIVE DATA BASE; AND (2) TO EVALUATE AND DETERMINE THE TECHNOLOGICAL REQUIREMENTS FOR… more
Company: Susquehanna Resources And Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: N/A
Displaying 6126 – 6150 of 6531 Awards
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