Abstract:O-glycosylation is one type of important protein modification and plays crucial roles in many cellular processes. Currently, there is limited commercial source for the glycosyl amino acid building blocks that can be utilized in glycopeptide synthesis. Inthis Phase I project, Life BioScience Inc.… more
Abstract:In this Phase II effort, SK Infrared LLC, is collaborating with Raytheon Vision Systems (RVS) to demonstrate a dual color 512x512 30 um pitch long wave/long wave (LW/LW) pBp focal plane array (FPA) hybridized to a RVS SB410 Read Out Integrated Circuit (ROIC). The SB410 is a 512x512 30 micron pitch… more
Abstract:This Small Business Innovation Research Phase I Project proposes to develop a novel non-invasive diagnostic imaging tool for the early detection of skin cancer. In this project, a controlled temperature stimulus is applied to the suspected lesion and the thermal recovery process is captured with an… more
Abstract:NASA has proposed several missions to land a craft on an asteroid and potentially to return samples from it. While large asteroids in the asteroid belt can exhibit a significant amount of gravity, most near-earth asteroids are small and show a surface gravity of less than 0.1% of earth. Landing,… more
Abstract:A large body of historic paper- and film-based seismograms are in storage, containing within them significant stores of seismological information. This information is unavailable for analysis because it needs to be extracted from its analog form and put into modern digital formats. National security… more
Abstract:ABSTRACT: The overall objective of this program is to develop a robust, state-of-the-art, remote data recovery (RDR) system for on-board data acquisition (OBDA) and fuzing systems used during weapon development research programs. The Phase I effort will include supporting a technical start-up… more
Abstract:It is extremely important to understand the temporal characteristics of electron beams at accelerator photoinjectors. Measuring and setting the electron bunchlength is critical to the operation of the accelerator, and can ultimately determine if physics experiments at user-based accelerators can be… more
Abstract:The objective of this proposal is to describe the design and technique behind a novel framing 2-dimensional (2-D) hyperspectral imager system that overcomes the limitations of traditional hyperspectral systems when tracking high speed targets and is capable of placing a 2-dimensional spatial grid on… more
Abstract:ABSTRACT: A new differential spectroscopic technique is proposed to detect VOCs for environmental monitoring and remdiation at Edwards AFB. This new technique has demonstrated promise with similar materials and can be deployed in a modestly sized unit to provide continuous monitoring. BENEFIT: … more
Abstract:Management Sciences"EdgeWare is motivated by the needs of warfighters to understand and negotiate the complex environments in which they are deployed. EdgeWare is an Edge Enabled System (EES) framework that will leverage and enhance the situation awareness (SA) of dismounted warfighters. Using… more
Abstract:MSI proposes to develop automated mechanisms to dissect incoming queries and engage appropriate cloud-based resources to address them. To automate this process, we propose iterative query refinement between an automated analyzer (called the Matchmaker) and human experts. The Matchmaker will use… more
Abstract:Sensing of greenhouse gases including, but not limited, to carbon dioxide and methane, throughout the atmosphere are needed to verify gas fluxes and concentrations in order to understand the terrestrial carbon cycle. Unmanned aerial vehicles (UAV) can provide the speed, range, and steering needed… more
Abstract:Mesa Photonics proposes development of a passive optical sensor for simultaneous high-precision measurement of oxygen and carbon dioxide profiles within the full atmospheric column. The approach, which is based on near-infrared heterodyne spectroscopy using solar occultation (i.e., direct solar… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will demonstrate a new method for monitoring carbon capture and storage (CCS) sites. CCS reduces global warming by using deep geological formations to store large amounts of carbon dioxide formed at power plants or separated from natural… more
Abstract:This Small Business Innovation Research Program (SBIR) Phase I project will develop improvements to multiphoton microscopy, especially two-photon excitation fluorescence (TPEF). This technology has radically changed the manner in which quantitative biological studies are performed. It is now the… more
Abstract:ABSTRACT: The goal of this phase II proposal is to develop a commercial platform for printing high performance, single-walled carbon nanotube transistor circuits on large-area plastic substrate. Automated processes will be developed for the room temperature printing of metal, semiconductor, and… more
Abstract:Ambient methane makes a substantial contribution to the greenhouse gas effect. Rapid, widespread accurate measurements of ambient methane concentration are needed to include in environmental models. D.O.E. is particularly interested in methane measurements in the Arctic where rapid climatic change… more
Abstract:Knowing atmospheric 13CO2/12CO2 ratios precisely is important to understanding biogenic and anthroprogenic sources and sinks for carbon. However, instruments currently available have attributes that are not favorable for distributed UAV deployment; they are large, require a lot of power, are very… more
Abstract:Monitoring the root systems of plants is essential to improving models of crop productivity, soil carbon sequestration and biogeochemical cycling. Fine roots (considered to be smaller than 1-2 mm in diameter) are the dominant component of this system, with roots & lt;0.2 mm in diameter often… more
Abstract:Past industrial practices have resulted in groundwater that is contaminated by heavy metals. Long-term monitoring and maintenance is one of the largest costs of environmental management. This project is developing a compact analyzer for measuring chromium ions in ground water that should… more
Abstract:The Compound Specific Analyzer?Combustion Products, used on the International Space Station as a warning monitor of smoldering or combustion events, is being phased out of service. Southwest Sciences Inc. proposes to develop a replacement laser-based analyzer using wavelength modulation… more
Abstract:This Phase I research project will investigate a novel method of operating an atomic magnetometer to simultaneously measure total magnetic fields and vector magnetic fields. Magnetometry has provided critical scientific information throughout the history of space exploration. The ideal magnetic… more
Abstract:Ensuring a safe air environment in manned spacecraft is critical to the success of all missions. Exposure to hazardous chemical species threatens the well-being of the crew and prevents them from fulfilling their tasks. While a wide variety of sensors currently are available to monitor such… more
Abstract:The development of rocket-based and turbine-based combined cycle engines are a high priority for transportation into space. In order to test components and systems, and certify life cycles for these engines, non-intrusive flow diagnostics are required. In particular, high-speed measurements of… more
Abstract:X-ray fluorescence spectroscopy is a widely used and extremely sensitive analytical technique for qualitative and quantitative chemical analysis. Superconducting Transition Edge Sensor (TES) microcalorimeter detectors have now been developed that achieve an energy resolution of 2 eV for 1.5 keV… more
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