Abstract:DESCRIPTION (provided by applicant): The global burden of cancer doubled between 1975 and 2000. Cancer became the leading cause of death worldwide in 2010, and is projected to double again by 2020 and to triple by 2030. This horrible disease has touched each of us, and despite enormous investments… more
Abstract:DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the leading cause of death in the world. The staggering mortality rate is expected to increase significantly in the next ten years. In the U.S., an estimated 81 million adults will haveone or more types of cardiovascular disease… more
Abstract:DESCRIPTION (provided by applicant): In both animal proof of concept studies and preliminary clinical trials, there is ample data demonstrating the potential therapeutic benefits o CD154 blockade for treatment of autoimmune diseases and organ transplantation. However, development of ?CD154 as a… more
Abstract:A key technology enabler for next generation EMI shielding applications is low loss, lightweight, flexible, conductive carbon nanotube (CNT) tape. The primary goal of this effort is to determine the optimal geometry for a CNT based EMI shield to provide equivalent shielding effectiveness of cable… more
Abstract:High-sensitivity resonant vibratory microelectromechanical systems (MEMS) sensors are typically vacuum packaged in discreet packages. Wafer-scale vacuum packaging offers size, weight, and cost advantages, and the packages are more shock and vibration tolerant. However, the high internal pressures… more
Abstract:Ocean bottom acoustic surveys are an important component of a number of littoral missions. Knowledge of local ocean bottom acoustic properties is necessary for modern anti-submarine warfare (ASW) and mine and other buried object detection missions to be successful. Bottom-hugging Unmanned Undersea… more
Abstract:Although helmeted divers are routinely exposed to noise levels that pose an increased risk of hearing damage, modern dive helmets do not include additional hearing protection. Noise sources from underwater tools, breathing noise, and high-volume communications all contribute to a dangerous noise… more
Abstract:Future NASA Space Science Missions will incorporate detectors, sensors, shields, and telescopes that must be cooled to cryogenic temperatures. An enabling technology for these missions is advanced cryocoolers that can provide continuous and distributed cooling with minimal input power. On this… more
Abstract:This proposal is responsive to NASA SBIR Topic X10.01, specifically, the need for efficient small- to medium-scale hydrogen liquefaction technologies, including domestically produced wet cryogenic turboexpanders. Future NASA missions will require hydrogen liquefaction systems for spaceport,… more
Abstract:Hybrid turbo-electric aircraft with gas turbines driving electric generators connected to electric propulsion motors have the potential to transform the aircraft design space by decoupling power generation from propulsion. Resulting aircraft designs such as blended-wing bodies with distributed… more
Abstract:Thermal and environmental control systems for future exploration spacecraft must meet challenging requirements for efficient operation and conservation of resources. Regenerative CO2 removal systems are attractive for these missions because they do not use consumable CO2 absorbers. However, these… more
Abstract:Future space exploration missions require advanced thermal control systems (TCS) to dissipate heat from spacecraft, rovers, or habitats to external environments. We propose to develop a lightweight, reliable TCS to effectively maintain cabin and equipment temperatures under widely varying heat… more
Abstract:In situ resource utilization (ISRU) is essential for several of NASA's future flagship missions. Currently envisioned ISRU plants include production of oxygen from hydrogen reduction of lunar regolith and extraction of water from Martian regolith or asteroid material. These ISRU processes… more
Abstract:ABSTRACT: Inspection of machined composite laminate parts is currently performed using a precision milling machine (PMM) to maneuver a touch probe. When performed on complex parts, this inspection process is extremely time consuming and ties up the PMM for longer time periods than the actual… more
Abstract:ABSTRACT: Future airborne imaging sensors will utilize next-generation focal plane technology that must operate at temperatures from 25 to 30 K. Passive cooling techniques such as stored cryogens are heavy and logistically undesirable. Current airborne cryocoolers are too inefficient in this… more
Abstract:ABSTRACT: CubeSats provide a new, low-cost platform for space weather missions. They enable new mission paradigms, such as the ability to perform multiple measurements of the same physical phenomena globally from several satellites, in contrast to high accuracy measurements of multiple phenomena… more
Abstract:ABSTRACT: The efficient, effective balancing of jet engine rotors and subassemblies continues to be a challenge for key aerospace applications. While manufacturing methods for balancing have improved significantly over the last ten years, measurement methods and procedures and fixturing have not… more
Abstract:ABSTRACT: Next-generation thermal management systems in advanced aircraft must utilize all available heat sinks, including fuel, ram air, and bleed air flows to effectively manage aircraft thermal loads. To this end, we propose to develop a compact, highly integrated condenser to prevent heat… more
Abstract:ABSTRACT: Dual-mode scramjet engines must operate over a wide range of flight Mach numbers. Closed loop engine control is necessary to maintain thrust and flame stability while preventing unstart over the large flight envelope. High-frequency sensors and actuators will be a key component of… more
Abstract:Small manned and unmanned aircraft need advanced propulsion technology to increase mission capabilities and improve reliability. We propose to develop an innovative recuperator technology that can significantly reduce fuel consumption for small gas turbines. Our microchannel recuperators are built… more
Abstract:The advanced properties achieved by modern ceramic matrix composite (CMC) structures depend critically on the surface condition of reinforcement materials used in the manufacturing process. Contamination of reinforcement surfaces can result in brittle phases, low melting point eutectics, or foreign… more
Abstract:Sand and dust ingestion can be a significant issue for military aircraft operating in desert environments. For gas-turbine engines, ingested sand erodes engine components such as turbine blades, accelerating engine wear. Currently, no operational systems exist for tracking sand and dust loading in… more
Abstract:Cabling faults can be difficult to identify and locate when a large number of interconnections are used such as in the shipboard Machinery Control System. Ungrounded systems further complicate diagnosis, since signal voltages and currents are small amplitude. It often takes a considerable amount of… more
Abstract:Instrumented manikins are used to assess the risks of burn injuries and evaluate the ability of clothing and other protective equipment to mitigate the injury potential during compartment or flash fires or other thermal threats. Recent data indicate that fabric stresses due to body motion are… more
Abstract:Advanced underwater vehicles (unmanned underwater vehicles (UUVs), torpedoes, etc.) are key to achieving long-term objectives for undersea force projection and surveillance. Existing battery-based power systems for these vehicles do not meet mission requirements due to low energy density,… more
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