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Displaying 1926 – 1950 of 2193 Awards
Company: Biotherm, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 2
Abstract: AN ASSAY SYSTEM FOR MONITORING FUNCTIONAL FIBRINOGEN IN PATIENTS UNDERGOING THROMBOLYTIC THERAPY WILL BE DEVELOPED. THIS SYSTEM WILL BE BASED ON A NOVEL DRY REAGENT ASSAY TECHNOLOGY THAT HAS RECENTLY BEEN APPLIED SUCCESSFULLY TO PTAND ACTIVATED PTT TESTS. INTRODUCTION OF A RAPID, CONVENIENT,… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: DOE / SBIR / 1992 / 2
Abstract: BORON NEUTRON CAPTURE THERAPY (BNCT) HAS A CLEAR THEORETICALADVANTAGE OVER OTHER TECHNIQUES AS A METHOD OF DELIVERING CELL-KILLING RADIATION TO CANCEROUS TUMORS. COMPOUNDS CONTAINING THE ELEMENT BORON, SUCH AS BORONOPHENYLALANINE (BPA), CAN ALSO SELECTIVELY LOCALIZE IN SKIN CANCERS SUCH ASMALIGNANT… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: DOE / SBIR / 1992 / 1
Abstract: N/A
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: N/A
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: NASA / SBIR / 1992 / 1
Abstract: N/A
Company: DIGITAL OPTICS CORP. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: PLEX Corporation will demonstrate a highly efficient laser emitting light at 1100nm in the near infrared. Technical issues in laser design will be resolved in Phase I, with a full lasing test experiment in Phase 2. This laser candidate has potentially a 25% electrical efficiency and can, in… more
Company: DIGITAL OPTICS CORP. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: N/A
Company: ELCATECH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 2
Abstract: THE INABILITY TO DETECT TOXINS WITH ADEQUATE SENSITIVITY IS ONE OF THE PRINCIPAL REASONS THAT THEY ARE POTENTIALLY THREATENING, EITHER DUE TO "NATURAL" EXPOSURE OR DELIBERATE AND HOSTILE USE OF THESE AGENTS BY AN ADVERSARY. THIS PROPOSAL OUTLINES A WAY THAT THE DETECTION OF THESE TOXINS CAN BE MADE… more
Company: ELCATECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: DURING THE DEVELOPMENT OF OUR FIBRINOLYTIC ASSAY SYSTEM WE NOTED AN ENHANCEMENT OF FIBRINOLYTIC ACTIVITY IN PLASMA WHICH COULD NOT BE ACCOUNTED FOR BY ANY KNOWN FIBRINOLYTIC FACTOR. USING HEPARING AFFINITY CHROMATOGRAPHY, WITH A 0.5M NAC1 ELUTION AND AN IMMUNO AFFINITY COLUMN WE HAVE BEEN ABLE TO… more
Company: ELCATECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: PLASMINOGEN ACTIVATION IS MODULATED BY A NUMBER OF INHIBITORS. THE FAST ACTING INHIBITOR OF T-PA AND U-PA HAS BEEN DESIGNATED PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1). THE DETECTION OF RAISED LEVELS OF THIS ACUTE PHASE PROTEIN IS INDICATIVE OF AN IMBALANCE IN THE HEMOSTATIC SYSTEM. IN ORDER TO… more
Company: Eldersource Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: N/A
Company: GENE TEC CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: N/A
Company: INTEGRATED LABORATORY SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: N/A
Company: Learning Services Corpon Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THIS PROJECT WILL DEVELOP, VALIDATE, AND MARKET A FUNCTIONAL-INTEGRATED REHABILITATION CURRICULUM FOR USE WITH HEAD INJURED ADULTS. THE CURRICULUM WILL FOCUS ON EMBEDDING COGNITIVE RESTRAINING INTO DAILY, FUNCTIONAL ACTIVITES OF HEAD INJURED INDIVIDUALS AS A COMPLEMENT TO TRADITIONAL COGNITIVE… more
Company: Lloyd K Konneker Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE PROJECT WILL MEASURE THE ACCURACY OF AN INFRARED PEOPLE-TRACKING SYSTEM. THE MAIN LONG-TERM OBJECTIVE IS TO AID HEALTH CARE OF THE ELDERLY IN THE HOME. PEOPLE-TRACKING SYSTEMS IN HOMES OF THE ELDERLY WILL HELP ORIENT THE CONFUSED, HELP THE ELDERLY FIND THEIR EQUIPMENT, HELP ALERT EMERGENCIES,… more
Company: Macronex, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE OBJECTIVES OF THIS APPLICATION ARE TO OPTIMIZE AND TO BEGIN THE PHARMACEUTICAL DEVELOPMENT OF TWO NOVEL THERAPEUTICS FOR THE TREATMENT OF ALLOGRAFT REJECTION OR AUTOIMMUNE OR INFLAMMATORY DISEASES. SPECIFICALLY, WE WILL: 1) OPTIMIZE AS TO LENGTH AND AMINO ACID COMPOSITION A HOMODIMER OF A… more
Company: Macronex, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE OBJECTIVES ARE TO OPTIMIZE AND BEGIN THE PHARMACEUTICAL DEVELOPMENT OF CHEMICALLY- DERIVATIZED POLYMERS OF LYSINE FOR USE AS THERAPEUTICS IN THE TREATMENT OF GRAFT REJECTION, AUTOIMMUNE DISEASES, OR ARTHRITIS. SUCH DERIVATIZED POLYMERS HAVE BEEN SHOWN TO INHIBIT THE EXPRESSION OF CLASS II (IA)… more
Company: Macronex, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) HAS BEEN IMPLICATED AS A POTENTIAL RISK FACTOR FOR MYOCARDIAL INFARCTION AND AS AN INHIBITOR OF PHARMACOLOGICAL THROMBOLYSIS. TRANSFORMING GROWTH FACTOR-BETA (TGF-BETA), A MAJOR CONSTITUENT OF PLATELET LYSATES, INDUCES PAI-1 RELEASE FROM VASCULAR ENDOTHELIAL… more
Company: QUANTUM RESEARCH SERVICES Agency/Program/Year/Phase: NSF / SBIR / 1992 / 1
Abstract: WE PROPOSE TO DEVELOP THE RUDIMENTS, IN PHASE I, OF A SOFTWARE SHELL THAT WILL ALLOW TEACHERS AND OTHERS INTERESTED IN SCIENTIFIC EDUCATION TO CONSTRUCT SPECIFIC SCIENTIFIC "EXPERIMENTS" ON PERSONAL COMPUTERS. THE SHELL WILL INCORPORATE A GRAPHICAL USER INTERFACE, ALREADY DEVELOPED IN PREVIOUS WORK,… more
Company: QUANTUM RESEARCH SERVICES Agency/Program/Year/Phase: NSF / SBIR / 1992 / 1
Abstract: WE PROPOSE TO INVESTIGATE IN PHASE I A VOLUME-SPECIFIC, LIMITED-SCAN PHOTON BACKSCATTER TECHNIQUE FOR THE DETECTION OF LOCALIZED CHANGES IN COMPOSITION AND/OR THICKNESS OF A LAYER HIDDEN UNDER A SURFACE LAYER, AS A GENERIC ANALOGUE OFTHE HIDDEN CORROSION PROBLEM. FEATURES INHERENT IN THE… more
Company: QUANTUM RESEARCH SERVICES Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THIS RESEARCH PROJECT SEEKS TO DEVELOP A MODEL FOR A LOCAL LEGISLATIVE TRACKING SYSTEM FOR CANCER CONTROL POLICIES RELATED TO SMOKING. THE MODEL WILL ADDRESS ALL ASPECTS OF AN EFFECTIVE LEGISLATIVE TRACKING MECHANISM, INCLUDING DATA SOURCES, DATA COLLECTION, DATA STORAGE, DATABSE MANAGEMENT, SYSTEM… more
Company: QUANTUM RESEARCH SERVICES Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THIS PROJECT SEEKS TO CONSTRUCT, TEST AND PREPARE FOR A LATER CLINICAL TRIAL (BY OTHERS), A FLYING-SPOT INFRA-RED (IR) OR NEAR-IR TRANSILLUMINATOR, WHICH MIGHT HAVE USE AS AN ADJUNCTIVE BREAST-CANCER EXAMINATION MODALITY. THE INSTRUMENT DIFFERS FROM PREVIOUS DESIGNS BY THIS AND OTHER GROUPS IN THAT… more
Company: Research Triangle Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE FORMATION OF MICRODROPLET FORMULATIONS OF A DRUG, A MEANS OF IMPROVING TISSUE COMPATIBILITYAND OF PROVIDING SUSTAINED RELEASE, INVOLVES THE PREPARATION OF MICROSPHERES (O.1 MICRON DIAMETER) OF A DRUG-CONTAINING OIL PHASE, AND THEIR ENCAPSULATION WITH A LAYER OF PHOSPHOLIPID.A RAT MODEL WILL BE… more
Company: Sean R Maloney & Company Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: N/A
Displaying 1926 – 1950 of 2193 Awards
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