Abstract:DESCRIPTION (provided by applicant): Stroke is the leading cause of adult disability and the third leading cause of death in the United States. Approximately 15 million people in the world, and more than 700,000 people in the United States, experience a stroke each year. Following a hemispheric… more
Abstract:DESCRIPTION (provided by applicant): Advanced Medical Electronics proposes to develop an advanced wireless hearing aid that tracks user head movements and provides automatic audio source switching based on user focus. The proposed advanced hearing aid willenable users to utilize hearing aids in more… more
Abstract:DESCRIPTION (provided by applicant): Advanced Medical Electronics (AME) proposes a wireless hearing aid accessory that utilizes gaze tracking of the hearing aid user's eyes by a smartphone's front facing camera to electronically steer a microphone array with signal processing. The… more
Abstract:DESCRIPTION (provided by applicant): This proposed project aims to develop an advanced telemetry system for body worn continuous glucose sensors using a new radio based on distance-bounded ultra wideband impulse radio technology for secure, reliable, low cost, low power body area sensor networks.… more
Abstract:DESCRIPTION (provided by applicant): Advanced Medical Electronics Corporation (AME) and the University of Minnesota propose to develop a new graphene based continuous glucose monitor with passive wireless readout capability and dissolvable / biocompatiblemetallization layers for use in close-loop… more
Abstract:Constructing, maintaining, and adapting operational procedures for manned space operations is a complex task, requiring the procedure author to satisfy constraints resulting from the system configuration, current state, and applicable flight rules. This Phase 1 SBIR project will establish the… more
Abstract:Hypervisors could significantly increase mission utility and life of space platforms, while decreasing acquisition time and cost. Terrestrial hypervisor applications, including cloud computing and avionics for Unmanned Aerial Systems, enjoy the benefits of maintenance, short-duration missions, and… more
Abstract:A microphone array system for studying the near field hydrodynamic region adjacent to the supersonic exhaust plume of a tactical aircraft engine in a ground test fixture at approximately 20 feet above the ground. It will consist of approximately 160 microphones aimed radially inward at the edge of… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project addresses the analysis needs for monitoring perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in water. PFOA and PFOS are ubiquitous environmental contaminants that have been found at low concentrations in waste… more
Abstract:Applied Colloids proposes the utilization of its proprietary nanotechnology in order to insure continued operation of powertrain transmissions utilized in rotorcraft. This will entail the use of a nanoadditive to the transmissions of interest. These nanoadditives will coat the interacting gears with… more
Abstract:DESCRIPTION (provided by applicant): The proposed SMART mount, a powered mounting and positioning system, provides individuals with significant disabilities access to and control over their immediate environment. It enables independent repositioning of devices by a person with little or no upper… more
Abstract:DESCRIPTION (provided by applicant): Pancreatic cancer represents the 10th most common cancer diagnosis, yet the 4th most common estimated cause of death. The only potential curative therapy for pancreatic cancer is surgical resection; however, few patients have tumors which can be respected.… more
Abstract:DESCRIPTION (provided by applicant): This project will establish proof-of-concept for a powerful and versatile implementation of live-cell assays in a true high-throughput screening (HTS) format for small-molecule drug discovery. The technological basis isfluorescence lifetime (FLT) readout of FRET… more
Abstract:DESCRIPTION (provided by applicant): The ultimate goal of this project is to develop a safe and effective topical vaccine against the dengue virus (DENV). DENV causes an estimated 30 to 50 million cases of debilitating fever leading to over 20,000 deaths worldwide every year. DNA-based vaccines have… more
Abstract:The design, fabrication, characterization, and preclinical evaluation of novel nanoparticle-based drug formulations capable of delivering candidate RNAi therapeutics for the treatment of cancer. PUBLIC HEALTH RELEVANCE
Abstract:DESCRIPTION (provided by applicant): Alzheimer's disease and related dementias (ADRD) are an urgent healthcare challenge facing 21st Century America. In the U.S. in 2011, one person received an ADRD diagnosis every 68 seconds; by 2050, that number will beone every 33 seconds (Alzheimer's… more
Abstract:DESCRIPTION (provided by applicant): As the US population ages, Alzheimer's disease and related disorders (ADRD) will present an emotional and financial burden to an increasing number of families and the U.S. healthcare system. More than 75% of the care for persons with ADRD is provided by… more
Abstract:ABSTRACT: A better understanding of the thermo-mechanical response, characteristics and properties of materials can lead to improved device performance as well as facilitate the design of new devices and materials for various applications. Although there has been significant progress in the… more
Abstract:DESCRIPTION (provided by applicant): Eden Medical proposes to develop a Self-Sealing Therapy Ostomy Pouch (S2TOP) to stop leakage that leads to skin breakdown and trauma for ostomy care patients. The S2TOP will detect leakage, inform the patient, and prevent leakage occurrence providing better… more
Abstract:Northern Technologies International Corporation (NTIC), MN, in collaboration with Michigan State University (MSU), MI, pans to formulate and engineer chemically modified, marine biodegradable, biofiber-based, non-plastic waste bags that are water resistant, readily treatable with other organic… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project is designed to offer two uniquely tailored thermoresponsive surfaces for the attachment and release of weakly and strongly adherent cells. The commercially available surfaces are highly crosslinked hydrogels that do not work well with… more
Abstract:The Department of Defense is continually looking for opportunities to reduce the weight of fixed-wing aviation assets. Reduced weight translates to a number of significant economic and operational benefits. One area of significant opportunity for increased weight savings is wiring, which is based on… more
Abstract:In atmospheric aerosol research, size-distributed aerosol samples are often collected with airborne instrumentation, but are not analyzed in any manner until after they are brought to a laboratory on the ground. The information thus obtained is averaged for all the locations covered during the… more
Abstract:DESCRIPTION (provided by applicant): This project will provide a significantly improved method for intra-pulmonary drug delivery in pediatric patients who are intubated or have a tracheostomy. Currently available aerosolizing devices are limited in that only certain agents and only a small fraction… more
Abstract:In ballistic missile defense (BMD), sensor placement and sensor-to-target assignment are daunting tasks; even one missed threat has devastating consequences. The Missile Defense Agency (MDA) seeks innovative algorithms for sensor coordination that recommend placement and response options in… more
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