Abstract:DESCRIPTION (provided by applicant): Structurally varied glycans displayed unexpectedly strong efects on inflammation and cancer progression. Glycan recognition by glycan-binding proteins is involved with physiological and disease-related cell adhesion orcell signaling. Tumor tissues secrete… more
Abstract:This Small Business Innovation Research Phase I project will modify an electric field sensor, developed to study dust electrification for it be used in industrial applications. The buildup of electric charges on the surface of materials is frequently large enough to cause electrostatic discharge… more
Abstract:This Small Business Innovation Research Phase I project will demonstrate proof of concept and determine the feasibility of a micro-laser assisted machining (micro-LAM) process that will both reduce the time, cost, and effort, and extend the capability, associated with machining of hard and brittle… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a linear, interleaved magnetic motor (LIMM). Magnetic motors are transducers, which convert electrical power into mechanical power according to the Lorentzian force function,F=B×li, where F is Force, B is magnetic flux, l… more
Abstract:This Small Business Innovation Research Phase I Project addresses the challenge of automating and scaling formal equivalence verification between architectural ESL/TLM SystemC models and RTL Verilog models for microprocessors and ASIC microcontrollers. The complexity of industrial processors,… more
Abstract:This Small Business Innovation Research (SBIR) Phase II Project advances CohortFS, a replicated, parallel storage platform for cloud computing. CohortFS offers unique capabilities for data partitioning, secure data access and retention, and flexible management of storage at very-large scale, with… more
Abstract:Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) that primarily affects the lungs. Approximately one third of the world"s population is latently infected with Mtb and at risk for developing active TB disease. Mtb grows slowly with visible growth appearing on solid media… more
Abstract:ABSTRACT: This project will investigate the feasibility of converting carbon dioxide (CO2) and water into liquid hydrocarbon fuel using solar energy and the same thermodynamic principles that enable biological photosynthesis; however, existing industrial technologies and processes will be… more
Abstract:ABSTRACT: Ultracapacitors are attractive energy storage devices due to their high cycle life, extremely high charge/discharge rates, and very low degradation rates. Improving ultracapacitor specific energy to 30 W-hr/kg or more would provide important functional benefits enabling a wide variety of… more
Abstract:ABSTRACT: BT Engineering proposes a three pronged approach to prevent and adversary from compromising military hardware and particularly space assets. This proposal deals primarily with preventing the means of triggering a malignancy built into the system. We propose three methods that, if used… more
Abstract:At the heart of the US armed services"effectiveness is their extensive background training. US soldiers, airmen, and others are put through exhaustive training, and their warfighting effectiveness is directly related to the quality of the training received. Part of this training includes live… more
Abstract:Most systems we interact with are dynamic systems and among those, multibody systems are pervasive. A multibody system is any physical system which may be modeled as interconnected rigid or flexible bodies which includes all manner of machines and mechanisms ranging from terrestrial vehicles and… more
Abstract:Embedded optical waveguides, with their inherently large transmission bandwidth capabilities, can be utilized to achieve digital transmission speeds that are not possible using copper trace interconnects. Single mode waveguides are not as limited by modal dispersion when compared to multi-mode… more
Abstract:The purpose of this team effort by Solidica and Navmar Applied Sciences Corporation-Advanced Acoustics Section effort is to demonstrate the feasibility of using Ultrasonic Additive Manufacturing (UAM) to build major components of an underwater sonar transducer. UAM has the ability to create new… more
Abstract:DESCRIPTION (provided by applicant): Ultrasound tomography is an emerging modality for breast imaging. However, current ultrasonic tomography's imaging algorithms, hindered by the limited memory and processor speed of computers, are based on ray theory andassume a homogeneous background, which… more
Abstract:DESCRIPTION (provided by applicant): Mammography is the current cost-effective gold standard for breast cancer screening. However, its usefulness has recently become a subject of considerable debate. The limitations of mammography are most evident in the population of women who have dense breast… more
Abstract:DESCRIPTION (provided by applicant): Death of photoreceptor cells is a consequence of many acute as well as chronic retinal diseases which lead to severe vision loss in patients. If photoreceptors could be helped to survive the period of disease, the visual outcomes for patients would be… more
Abstract:DESCRIPTION: Synthetic Biology is full of promises ranging from discovery and production of new drugs, targeted therapies modifying organisms such as yeast or E. coli or creating totally new ones, higher crop yields, CO2 sequestration to bio-energy projects. However, these goals have been difficult… more
Abstract:As recognized by the National Nanotechnology Initiative and the Department of Energy, Scanning Probe Microscopes are vital to the advancement of nanoscience and nanotechnology. Although there has been a steady improvement in the capabilities of commercial Scanning Probe Microscopes, instruments… more
Abstract:ABSTRACT: This STTR proposal is the natural consequence of our collaboration that makes use of the established know-how under the MURI program, the established track record of RHK in commercialization of critical hardware, software and electronic controllers to implement scanning probe microscopy… more
Abstract:The objective of this proposal is to establish the feasibility of developing an integrated decision support framework that transforms the current time-consuming and reactive (post completion of final design) sustainability assessment into a proactive CAE approach that enables the ability to revise… more
Abstract:Our vision is that of an integrated decision support solution that transforms the current time-consuming and reactive (post-design) sustainability assessment of a product into a proactive approach available in the early design phases. This solution called Sustainability Integrated into Early Design… more
Abstract:The objective of this proposal is to demonstrate the feasibility of a fully packaged microelectromechanical (MEMS) gyroscope with a 7 milliarcsecond pointing accuracyÂ?sufficient for space and terrestrial telescope pointing applications. This new environmental resistant packaged (ERP) resonant… more
Abstract:The objective of this proposal is to demonstrate the feasibility of a vibration suppression technology tailored for crystal oscillator applications called the integrated vibration isolator for Quartz (IVIQ). Vibration is an important factor for Quartz timing applications since vibration causes… more
Abstract:An integrated, in-situ, real-time, optical metrology system will be developed to measure temperature, film stress and reflectivity during CdTe and HgCdTe-based deposition applications. Temperature measurement will be performed using band-edge thermometry and blackbody radiation analysis to provide a… more
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