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Displaying 7576 – 7600 of 7761 Awards
Company: Biox, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE DISCOVERY OF ONCOGENES, GENES WHICH CAUSE CANCER, HAS HAD A MAJOR IMPACT ON RESEARCH AND POTENTIAL DIAGNOSIS AND TREATMENT OF CANCER. SOME OF THE PRODUCTS OF ONCOGENES HAVE BEEN FOUND TO BE SIMILAR TO GROWTH FACTORS AND GROWTH FACTOR RECEPTORS WITH REGARD TO BIOLOGICAL ACTIVITIES AND AMINO ACID… more
Company: Biox, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: INFECTION BY HERPES SIMPLEX VIRUS (HSV) HAS BEEN ASSOCIATED WITH CERVICAL CANCERS. IN ADDITION, NEONATAL INFECTION BY HSV IS OFTENTIMES FATAL. THE CURRENTLY RECOMMENDED PROCEDURES FOR SCREENING PREGNANT FEMALES IN THE HIGH-RISK CATEGORY (I.E., HISTORY OF ACTIVE OR RECURRENT HSV INFECTION) INCLUDE… more
Company: Brandel, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: FROZEN SECTIONS FROM TISSUE BIOPSY HAVE BEEN ROUTINELY USED FOR DIAGNOSTIC PURPOSES FOR MANY YEARS, BUT PATHOLOGISTS REPORT DIFFICULTY IN ANALYZING ANY TYPE OF FROZEN SECTIONS FROM TISSUES CONTAINING VESICLES, SUCH AS EPIDERMAL, LIVER, LYMPH NODAL, TESTICULAR, OR INTESTINAL TISSUE, BECAUSE OF… more
Company: Braton Biotech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: IN THE ASSESSMENT OF GENOTOXICITY OF ENVIRONMENTAL CHEMICALS, A BATTERY APPROACH HAS BEEN RECOMMENDED. THE TESTING BATTERY IN GENERAL INCLUDES BACTERIAL AND RODENT MAMMALIAN CELLS AS TARGET ORGANISMS. DATA GENERATED FROM OUR COMPARATIVE EVALUATION OF THESE APPROACHES INDICATED THAT WHEN COMPARISON… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1985 / 2
Abstract: RECENT WORK PERFORMED AT NSWC, WHITE OAK, MD HAS SHOWN THAT CONVENTIONAL LAUE X-RAY TRANSMISSION PATTERNS OBTAINED BY FILM METHODS GIVE AN INDICATION OF GROWN-IN MICROSTRUCTURAL DEFORMATION OF HOLSTEN CLASS D RDX ENERGETIC MATERIALS. THE OBJECT OF THIS STUDY IS TO DETERMINE IF X-RAY LAUE PATTERNS… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1985 / 2
Abstract: THE PROPOSED RESEARCH WORK IS A RESPONSE TO THE NATIONAL DEFENSE EFFORT OF THE UNITED STATES OF AMERICA TO ULTIMATELY MANUFACTURE A LOW COST, RELIABLE AND EFFECTIVE TURNABLE FREQUENCY FAR INFRARED (IR) DETECTOR THAT CAN BE PLACED UPON BOTH OUR OFFENSIVE AND DEFENSIVE WEAPONS SYSTEMS. THE MATERIAL… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1985 / 2
Abstract: WITH THE DOD HGCDTE AND GAAS PROGRAMS MOVING TOWARD EPITAXIAL GROWTH TECHNOLOGY THERE IS A NEED TO DEVELOP REAL-TIME MATERIALS CHARACTERIZATION TECHNIQUES OF BOTH SUBSTRATES AND/OR EPITAXIAL FILMS QUICKLY FOR PRODUCTION ENVIRONMENTS. REAL-TIME X-RAY TOPOGRAPHY OF WHICH BRIMROSE IS A PIONEER IS ONE… more
Company: Business & Technological Syste Agency/Program/Year/Phase: NASA / SBIR / 1985 / 1
Abstract: AN APPROACH TO POSTLAUNCH VECTOR-SENSOR ALIGNMENT CALIBRATION IS PROPOSED WHICH PROVIDES OPTIMAL ESTIMATES OF SENSOR MISALIGNMENTS BASED ON GROUND-TESTING RESULTS AND INFLIGHT DATA. TWO TYPES OF ALGORITHMS ARE PRESENTED WHICH WOULD BE APPLICABLE EITHER TO SPACECRAFT WHICH DETERMINE ATTITUDE FROM… more
Company: Business & Technological Syste Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE FABRICATION OF MULTIELECTRODES FOR CHRONIC, SIMULTANEOUS RECORDING OF SINGLE NEURONS IN TISSUE CULTURES, PERIPHERAL NERVES, HIPPOCAMPUS, AND CEREBRAL CORTEX HAS PROGRESSED TO THE POINT WHERE THE VOLUME OF SINGLE-UNIT DATA IS NOW SIGNIFICANT. RECENT ADVANCES IN SIGNAL PROCESSING ARE BEING USED BY… more
Company: Capital Systems Group Inc Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE LONG-TERM OBJECTIVE OF THE PROPOSED PROJECT IS TO DEVELOP FOR MICROCOMPUTER IMPLEMEN-TATION: 1.AN INTEGRATED, USER-FRIENDLY STATISTICAL SOFTWARE PACKAGE TO ANALYZE EPIDEMIOLOGIC DATA, AND 2.A BIBLIOGRAPHIC FORMATTING PROGRAM TO ALLOW RESEARCHERS TO ACHIEVE THESE RESEARCH GOALS, THE FOLLOWING… more
Company: Capital Systems Group Inc Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE BENEFITS OF USING MICROCOMPUTERS IN HEALTH INSTRUCTION INCLUDE MINIMAL COST, MAXIMUM TEACHING EFFECTIVENESS, AND FLEXIBILITY TO MEET INDIVIDUAL LEARNING NEEDS. ALTHOUGH MANY NUTRITION SOFTWARE PROGRAMS ARE USED IN HOME, HOSPITAL, AND CLASSROOM SETTINGS, NO SUCH SELF-HELP PROGRAMS HAVE BEEN… more
Company: Capital Systems Group Inc Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THIS PROJECT WILL DESIGN, PROGRAM, EVALUATE AND DEMONSTRATE A SELF-HELP SINGLE USE CALCULATOR FOR ESTIMATING CALORIE AND FAT INTAKE TO WITHIN 1015% PER 24-HR PERIOD. THIS INSTRUMENT WILL BE TESTED INTERNALLY FOR 3 WEEKS AND FIELD TESTED FOR 12 WEEKS IN STUDY ENVIRONMENTS IN WHICH INVESTIGATORS ARE… more
Company: Cemcom Research Associates Inc Agency/Program/Year/Phase: DOD / SBIR / 1985 / 1
Abstract: N/A
Company: Center For Preventive Therapy Agency/Program/Year/Phase: HHS / SBIR / 1985 / 2
Abstract: THE SPECIFIC PURPOSE OF THIS PROJECT IS TO PROVIDE A METHOD TO REMOVE BARRIERS WHICH HINDER OR PREVENT THE EMPLOYMENT OF BLIND PERSONS. AN INNOVATIVE METHOD, CALLED THE LOZANOV LEARNING SYSTEM, IS PROPOSED TO HELP TRAIN BLIND PERSONS TO BECOME COMPUTER PROGRAMMERS AND OPERATORS OF AUTOMATED… more
Company: Chemical Dynamics Corp Agency/Program/Year/Phase: NSF / SBIR / 1985 / 1
Abstract: INFRARED MULTIPHOTON EXCITATION (IRMPE) INDUCED PROCESSES INMEDIUM SIZED AD SMALLER POLYATOMICS EXHIBIT SELECTIVITY THATCAN BE CENTRAL IN APPLICATIONS. STATISTICAL THEORIES DO NOTAPPLY AND QUANTUM APPROACHES BECOME FORMIDABLE. A SEMICLASSICAL THEORY OF THESE PROCESSES IS TO BE DEVELOPED FOR… more
Company: Cheung Laboratorytories, In Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Civilized Software, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: TESTING ITS IMMUNOTHERAPEUTIC POTENTIAL THE LONG-TERM OBJECTIVE OF THIS PROJECT IS TO DEVELOP PROCESSES FOR THE PRODUCTION OF B-CELL GROWTH FACTOR (BCGF) AND TO TEST THE POTENTIAL APPLICATIONS OF BCGF FOR THE TREATMENT OF HUMAN IMMUNOPATHOLOGICAL CONDITIONS. BCGF MAY BE USEFUL AS AN… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE OBJECTIVE OF THIS RESEARCH PLAN IS TO ISOLATE A CDNA SEQUENCE ENCODING TUMOR NECROSIS FACTOR (TNF) AND, BY MANIPULATION OF THAT SEQUENCE, TO PRODUCE AND SECRETE THE MATURE TNF PROTEIN FROM THE YEAST SACCHAROMYCES CEREVISIAE. PREVIOUS WORK ON TNF HAS SHOWN IT TO HAVE CYTOSTATIC OR CYTOLYTIC… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: LYMPHOTOXIN IS A LYMPHOKINE WHICH HAS POTENT ANTITUMOR ACTIVITY. IT IS A GLYCOPROTEIN WITH A MOLECULAR WEIGHT OF 25,000 DALTONS. DUE TO THE MINUTE AMOUNT PRODUCED BY LYMPHOCYTES, EVALUATION OF ITS PHARMACEUTICAL POTENTIAL REQUIRES THAT IT BE CLONED AND EXPRESSED IN A SUITABLE HOST. IN ORDER TO… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: WE PROMISE TO DEVELOP METHODS FOR THE LARGE-SCALE PRODUCTION OF HUMAN COLONY STIMULATING FACTORS (CSF) FROM NORMAL HUMAN PERIPHERAL BLOOD LYMPHOCYTES. THE FERMENTATION METHODS EMPLOYED WILL BE SIMILAR TO THOSE USED FOR THE PRODUCTION OF NATURAL INTERLEUKIN-2. WE ARE PRODUCING HUMAN IL-2 FOR CLINICAL… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: WE PROPOSE TO DEVELOP A METHODOLOGY BY WHICH THE GENES CODING FOR AUTOIMMUNE DISEASE-SPECIFIC PROTEIN ANTIGENS CAN BE RAPIDLY CLONED USING RECOMBINANT DNA TECHNIQUES. THE SYSTEM WHICH WE ARE USING LENDS ITSELF TO HIGH-LEVEL EXPRESSION OF THESE ANTIGENS AS HYBRID PROTEINS IN E. COLI. THIS FACILITATES… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: WE PROPOSE TO IDENTIFY THE GENES FOR AUTOIMMUNE DISEASE-SPECIFIC PROTEIN ANTIGENS BY THE USE OF RECOMBINANT DNA TECHNIQUES. THE SYSTEM THAT WE ARE USING LENDS ITSELF TO HIGH-LEVEL EXPRESSION OF THESE ANTIGENS AS HYBRID PROTEINS IN E. COLI. THIS APPROACH FACILITATES PRODUCTION OF THESE ANTIGENS FOR… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Displaying 7576 – 7600 of 7761 Awards
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