Abstract:DESCRIPTION (provided by applicant): The goal of this project is to discover lead compounds acting specifically against Helicobacter pylori, the causative agent of peptic ulcer and gastric carcinoma. Roughly every other person carries the pathogen, and there are an estimated 1.5 million cases… more
Abstract:DESCRIPTION (provided by applicant): The goal of this project is to develop a therapeutic acting specifically against Helicobacter pylori, the causative agent of peptic ulcer and gastric carcinoma. Roughly every other person carries the pathogen, and thereare an estimated 500,000 cases annually of… more
Abstract:Aspen Systems Inc. proposes a novel personal cooling system that uses a vapor compression chiller to circulate cooled water through flow channels in a wearable vest to facilitate improved cooling of personnel in high-temperature environments. The system is designed to cycle coolant delivered to… more
Abstract:Achieving very high-power amplification with maximum efficiency at X- and Ka-band is challenging using solid-state technology. Gallium Arsenide (GaAs) has been the material of choice for high-power microwave systems at these frequencies for decades. Until only recently, GaAs was unchallenged at Ka… more
Abstract:ABSTRACT: Auriga will produce an ultra-linear high-power, high-efficiency amplifier to be used in satellite communication systems. The innovative approaches are proposed and validated in Phase I. The enabling technology is Gallium Nitride (GaN) ,which is well-known for its power handling capability… more
Abstract:ABSTRACT: Phase I tasks will produce a full-duplex, multi-channel, S-band transmit-receive (T/R) module design and the associated panel structure for integration into large communication phased array antennas. An RF section featuring advanced, two-chip Monolithic Microwave Integrated Circuit (MMIC)… more
Abstract:This Small Business Innovation Research Phase II project proposes a robotic hand based on a novel torque-switching mechanism and patented miniature motor controllers. The mechanism actively channels motor torque along different transmission paths and enables dependant and independent (time-discreet)… more
Abstract:Beacon"s vision for this topic is to create an innovative tag-out capability coupled with the ability to capture human work performance data and provide that data to analysis tools such as the Engineering & Supportability Decision System (ESDS) and MFOM. Utilizing tag-out for this research… more
Abstract:Recognizing the advantages of energy storage flywheels in rapid-response, high cycle-life applications, ARPA-E has funded Beacon Power to develop critical components for a low cost flying ring hub-less flywheel under the GRIDS program. The funded system will provide 100 kW for 1 hour for firming and… more
Abstract:The Army is looking to research and develop a programmable multichannel radio frequency filter-equalizer having a programmable number of channels, each programmable with potentially unequal spacing, bandwidth, and equalization. What is needed is a digitally programmable multichannel filter-equalizer… more
Abstract:DESCRIPTION (provided by applicant): In this Phase I project, we propose to investigate a novel primer chemistry and probe detection system called the Zip nucleic acids (ZNA ). ZNAs are oligonucleotides conjugated to a number of cationic spermine moietiesthat enhance the effective concentration of… more
Abstract:DESCRIPTION (provided by applicant): Human respiratory syncytial virus (RSV) is a highly infectious member of the paramyxovirus family causing upper and lower respiratory tract infections. RSV infection is the leading cause of pulmonary disease of the lower respiratory tract (bronchiolitis,… more
Abstract:DESCRIPTION (provided by applicant): Rheumatoid arthritis is a chronic inflammatory disorder that afflicts at least 2.5 million Americans. This autoimmune disease is 2-3 times more common in women and typically affects the small joints in the hands and feet. Current therapeutic strategies include… more
Abstract:DESCRIPTION (provided by applicant): Current gold standards for hemodialysis access to treat End-Stage Renal Disease (ESRD), radial cephalic vein fistulas and autogenous saphenous veins, have significant problems associated with their use. The issues rangefrom unavailability of a healthy vein the… more
Abstract:Currently, assessment of ordnance items for IM and Hazards Classification (HC) characterization requires full-scale testing which presents a considerable financial, logistical, and environmental burden. Some of these munitions (such as the large rocket motors) cost in excess of a million dollars and… more
Abstract:We propose engineering models and incorporate them into Excel spreadsheet to evaluate the effects of ballistic and blast loadings on vehicle armors. The models are developed in innovative ways and run fast but maintain first-order accuracy. The software can be used to screen the design solutions… more
Abstract:We propose to develop a physics based, high accuracy and easy to use software for the fate and transport analysis of chemical and biological agents and contaminants in drinking water distribution systems. A recently developed BlazeTech software called H2OFate1.0 will be used as the platform for this… more
Abstract:ABSTRACT: Design and build a hyperspectral sensor that maintains high spatial resolution information. BENEFIT: To design and build a long wave infrared (LWIR) hyperspectral sensor system that is capable of placing enough pixels on target for shape-based target identification, while maintaining… more
Abstract:ABSTRACT: Measurements of combustion and gas dynamic properties inside gas turbine engines and augmentors are needed to aid in engine development, performance testing and evaluation, and for verification and validation of combustion modeling codes. Advanced instrumentation and flow-field… more
Abstract:ABSTRACT: The Air Force has a need for a wide-range, differential blackbody to test IR surveillance, targeting and tracking systems in the -40 degrees C to 100 degrees C range. Thermal controlled MRTD test blackbody will be developed that can operate over the full temperature range using thermal… more
Abstract:Boston Engineering"s Advanced Systems Group and Dr. Holly Yanco"s team at the University of Massachusetts at Lowell propose to develop a design science for robot operator interfaces and demonstrate its application through existing design tools and prototype systems that reduce operator… more
Abstract:ABSTRACT: Busek Co. Inc. and Massachusetts Institute of Technology (MIT) propose to explore the physical limits of ionic liquid propulsion via development of new theory to explain effects of close packing density and to predict performance limits. The research is motivated by observations and… more
Abstract:ABSTRACT: Busek Co. Inc. proposes to develop an advanced propulsion module with autonomous orbit control for ORS satellites. It will be fueled by low-toxicity liquid propellants and will provide as much as 329m/s delta-V to a 250kg spacecraft. Due to the stability and ease of handling of the… more
Abstract:ABSTRACT: A high power iodine propellant Hall Effect thruster system will be developed for orbit raising and other in-space applications. This system will include a thruster, hollow cathode, and propellant feed system. The Phase I thruster will have a power level of 1-3 kW. The Phase II thruster… more
Abstract:ABSTRACT: Busek proposes to developed a self-contained electrospray thruster that (a) requires no pressurized propellant tanks or valves, utilizes analog-only electronics, and stores propellant as a stable solid; (b) is capable of operation after extended storage and inoperative periods of up to 15… more
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