Abstract:DESCRIPTION (provided by applicant): The First Locally Acting Anti-Inflammatory Stem Cell-Based Therapy for Rheumatoid Arthritis Despite improved therapy; rheumatoid arthritis (RA) remains a significant unmet medical need. The long-term goal of this project is to advance the first stem cell-based… more
Abstract:DESCRIPTION (provided by applicant): CM101 is a polysaccharide tumor angiogenesis-targeting, complement activating, immune stimulating biological produced fermentatively from Group B Streptococcus. CM101 binds a capillary endothelium receptor, HP59, causing inflammatory cytokine cascades, recruiting… more
Abstract:Purpose: In prior research, prosocial behaviors in grade school have been correlated with later academic achievement while anti-social behaviors have been associated with later poor academic achievement and deviance. To help teachers monitor students' social behavior, this project will develop a… more
Abstract:As fish species with greater sensitivity to water quality are cultured in recirculating aquaculture systems (RAS), it becomes vital to improve fine solids capture. Additionally, phosphorous levels in the discharge from RAS are often high (per EPA guidelines and regulations) and can lead to… more
Abstract:ABSTRACT: The objective of this project is to develop nondestructive evaluation technology to locate and characterize defects and damage in ceramic matrix composite material with sufficient quantification to be usable in material performance models. The Evisive microwave interferometry technique… more
Abstract:The objective of this proposal is to develop a robust hand-held, tool for inspection of non-metallic armor while the armor is still mounted on ground vehicles. Impacts of sufficient energy, including those which are routine, like impact with road hazards, and handling incidents can damage the armor… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop a compact, metal-based, recirculating liquid cooling system for next-generation electronic devices. The dramatic increase in computing power over several decades has been accompanied by an equally dramatic increase in… more
Abstract:Mezzo Technologies fabricates high performance micro channel radiators, condensers, evaporators and Phase Change Material (PCM) heat exchangers. The attributes of Mezzo's products include high heat transfer/volume, heat transfer/weight, heat transfer/air side pressure drop, and unique geometry… more
Abstract:This Phase II SBIR will execute the research to commercialization process developed in Phase I, when WorldWinds, Inc. developed and implemented a procedure to showcase graphical NOAA products for on-air consumption by the general public. Through collaboration with Baron Services, Inc., of… more
Abstract:Today, the ability of sensors to generate geographical data is virtually limitless. Although NASA now provides (together with other agencies such as the USGS) a capability for accessing, manipulating, and visualizing these data, an enormous gap still exists between the sensor data and the… more
Abstract:This Small Business Innovation Research Phase I project proposes to develop and commercialize new types of silicon nanowire anodes which may be used to safely store large amounts of lithium for many types of lithium batteries. The key innovation involves unique functionalization and integration… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a next generation forensic human DNA typing system. DNA profiling has gained broad popularity since its first use 25 years ago. Its application has expanded from criminal and parentage issues to mass disasters and… more
Abstract:DESCRIPTION (provided by applicant): Pulmonary infection with the fungal pathogen, Pneumocystis jirovecii, is a common and often fatal complication of HIV infection/AIDS. Emerging data suggest that Pneumocystis may also complicate lung diseases in non-HIVinfected hosts including those with COPD and… more
Abstract:The primary focus of this proposed effort development of methods to allow for ultra fast wideband RF sensing and classification of unknown RF devices. In order for cognitive radio methods and techniques to be implemented substantial improvement in sensing and classification of non-cooperative RF… more
Abstract:BMB Discount Guns, Ammunition, and Supplies proposes to develop a novel form of dim tracer ammunition. This ammunition is a non-burning, chemically inert, constant mass tracer. This design of this dim tracer is such that it cannot be perceived by enemy forces, even with enhanced optics. This… more
Abstract:Through the Social Shape Up System teachers will use a handheld device to manage their classroom by monitoring and track classroom behaviors in pre-K to eighth grade classrooms. The product will include the curriculum consisting of eight research-based… more
Company:AQUA GREEN LLCAgency/Program/Year/Phase:USDA / SBIR / 2010 / 1
Abstract:Although baseline methods for growing high-value marine finfish in low salinity recirculating aquaculture systems (RAS) have been developed, the technologies for effective treatment of wastewater from RAS facilities operating at low salinity levels have not been explored to any great extent,… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project's overall goal is to commercialize a robust, continuous culture production system for rotifers (Brachionus rotundiformis; s-type), the major live feed source for marine larval fish. A major bottleneck in the expansion of the marine… more
Abstract:DESCRIPTION (provided by applicant): Between 10% and 20% of the United State population suffer from seasonal influenza each year. While most individuals recover from influenza in one to two weeks, the very young, the elderly and persons with chronic medica
l conditions can develop post-flu pneumonia… more
Abstract:DESCRIPTION (provided by applicant): 7-Butyl-10-aminocamptothecin (BACPT), as a water-soluble dipeptide pro-drug - BACPTDP, is a novel camptothecin analog that has increased activity in hypoxic/acidic tumor tissues, characteristic of fast growing cancers t
hat characteristically have deficient… more
Abstract:The numerous management tools currently employed for disaster response presents a barrier when attempting to share information
across boundaries. This impediment is due to the different reporting formats, data storages, or incompatibility of software being
deployed. Geocent proposes implementing… more
Abstract:We propose the development of a capability which will allow ecosystem managers to share a map view in terms of location, magnification level, and data layers (to include local data and sources) throughout the community of COAST users. This capability will foster collaboration and allow rapid… more
Abstract:Mezzo fabricates high performance micro tube heat exchangers. In this proposal, extremely light weight versions of these heat exchangers made from polymers will be examined for use on high altitude unmanned air vehicles (UAVs). The anticipated weight of these heat exchangers is expected to be… more
Abstract:The objective of this program is to develop techniques to reduce engine cooling system noise levels of the Expeditionary Fighting Vehicle (EFV). Mezzo's approach is to redesign the engine cooling heat exchangers (LTC, HTC, fuel cooler, and condenser) using Mezzo's heat exchanger technology to reduce… more
Abstract:Mezzo fabricates high performance micro tube heat exchangers. In the Phase I program, Mezzo explored substituting the stainless steel micro tubes that typically have been used with polymer micro tubes. Polymer micro tube heat exchangers have significant potential advantages over currently used metal… more
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