Abstract:We will develop and test a locating device worn on a person's body that can be used to locatepatients with dementia who have wandered away. Current technology used to protect wanderingpatients focuses on alerting caregivers to patient exits, but does not assist in locating patients once theyhave… more
Abstract:Formaldehyde is a common disinfecting agent in dialyzer membrane reuse procedures. Since formaldehyde is carcinogenic, toxic and malodorous, any safe, cost-effective alternative would be a marketable an medical success. The long-term objective is to benefit patient care, employee safety, and cost… more
Abstract:PRESENT DAY FIRE DETECTORS NORMALLY EMPLOY A SINGLE SENSOR, SUCH AS AN OPTICAL DENSITY OR IONIZATION DETECTOR, THAT HAS WELL KNOWN LIMITATIONS. ALARM DECISIONS ARE THUS BASED ON A SINGLE MEASUREMENT THAT IS OFTEN INACCURATE, AND INSENSITIVE. WE PROPOSE TO USE AN ARRAY OF VERY SMALL AND INEXPENSIVE… more
Abstract:More than 100,000 patients now receive chronic hemodialysis therapy in Medicare's End StageRenal Disease Program. Hemodialysis related amyloidosis affects a significant portion of these patients.The syndrome presents clinically as carped tunnel syndrome, cystic bone lesions, and arthropathies.… more
Abstract:THE AMERICAN ASSOCIATION OF PHYSICS TEACHERS DEVELOPED PHYSICS: CINEMA CLASSICS (PCC) VIDEODISCS. THE VIDEODISCS CONTAIN VIDEO CLIPS AND FILM LOOPS WHICH EDUCATORS HAVE SUCCESSFULLY USED FOR DECADES. RESEARCHERS ARE DEVELOPING ANCILLARY MATERIALS TO ENHANCE THE ACCESSIBILITY OF THE VIDEODISCS FOR… more
Abstract:THIS PROJECT DEVELOPS AND FIELD TESTS A PROTOTYPE SOFTWARE/HARDWARE ASSESSMENT PACKAGE TO SUPPORT ASSISTIVE TECHNOLOGY ASSESSMENT PERSONNEL RESPONSIBLE FOR SELECTION OF APPROPRIATE CONTROL INTERFACE DEVICES FOR PERSONS WHO HAVE DIFFICULTY INTERACTING WITH THEIR ENVIRONMENT. THIS POPULATION INCLUDES… more
Abstract:Sports Center Unlimited will be a simulated sports/leisure activity exploration program for youths with physical disabilities. The Phase I prototype will run on a Macintosh using QuickTime multi-media with sound, color, video, animation, and user interaction. As one of many animated characters, each… more
Abstract:There is evidence that the excitotoxic action resulting from excessive accumulation of L-glutamate plays a prominent role in human epilepsy and brain ischemia/stroke, leading to neuronal dysfunction and cell death. The triazolines and the aminoalkylpyridine metabolite analogues are a group of novel… more
Abstract:A CHEMICAL VAPOR MONITORING SYSTEM, INCORPORATING STATE-OF-THE-ART CHEMICAL MICROSENSOR AND MICROCOMPUTER TECHNOLOGIES, WILL BE DESIGNED AND OPTIMIZED FOR THE AUTOMATIC, CONTINUOUS, LONG TERM, LOW LEVEL MONITORING (BELOW 0.01 MG/M3) OF CHEMICAL AGENTS. THE INITIAL DEMONSTRATION UNIT WILL BE… more
Abstract:It is proposed to develop a small, pocket size personal monitor for glutaraldehyde based on the use of a Surface Acoustic Wave (SAW) chemical microsensor as the detector. SAW microsensors are attractive for this application as they are very sensitive to toxic chemicals of modest to low vapor… more
Abstract:OLDER ADULTS HAVE MORE TRAFFIC CONVICTIONS AND ACCIDENTS AND INCUR MORE FATALITIES PER MILE DRIVEN THAN ANY OTHER AGE GROUP. THE AIM OF THE RESEARCH IS TWO-FOLD: 1) TO TAKE THE RESEARCH PARADIGMS DEMONSTRATED TO BE RELATED TO A VARIETY OF EVERYDAY FUNCTIONAL VISION PROBLEMS IN OLDER ADULTS AND… more
Abstract:THE PROJECT DEVELOPS AND FIELDTESTS A COMMERCIAL PROTOTYPE SOFT- WARE/HARDWARE PACKAGE DESIGNED TO SUPPORT CHILDREN WHO HAVE LIMITED PHYSICAL CONTROL AND DIFFICULTY MAINTAINING APPROPRIATE POSTURE DUE TO NEOROLOGICAL DEFICITS. THE POSTURE MONITOR (PM) CONSISTS OF A MICROPROCESSOR-CONTROLLED… more
Abstract:IMMUNOLOGIC REJECTION IS THE LEADING CAUSE OF FAILURE OF RENAL TRANSPLANTATION. THE OBJECTIVE WILL BE TO DEVELOP AN ASSAY FOR MONITORING KIDNEY TRANSPLANT RECIPIENTS FOR THE ONSET OF GRAFT REJECTION AND TO HELP DISTIGUISH GRAFT REJECTION FROM OTHER RENAL AND EXTRARENAL PROBLEMS IN THESE PATIENTS.… more
Abstract:THE OBJECTIVE IS THE DEVELOPMENT OF METHODS AND REAGENTS FOR USE IN THE STUDY OF DELETION MUTATIONS AT THE MOLECULAR LEVEL. SUCH TECHNOLOGY HAS NOT BEEN DEVELOPED FOR THE ANALYSIS OF DELETION MUTATIONS WHICH ARE INDUCED BY AN IMPORTANT CLASS OF ENVIRONMENTAL MUTAGENS/CARCINOGENS AND IS NECESSARY FOR… more
Abstract:THIS PROJECT WILL DEVELOP, FABRICATE AND FIELD TEST AN ADAPTABLE SCANNING SELECION AID (ASSA) AND APPLICATION ACCESSORIES. THIS SYSTEM WILL PROVIDE PERSONS WITH LIMITED MOTOR FUNCTION AND/OR MINIMAL VERBAL COMMUNICATION SKILLS AND MEANS OF MAKING CHOICES IN THEIR ENVIRONMENT USING SIMPLE SWITCHES.… more
Abstract:THE PREPARATION OF PEPTIDES BY SOLID PHASE METHODS USUALLY REQUIRES A RAPID, RELIABLE, AND RACEMIZATION-FREE PROCEDURE TO ATTACH THE FIRST AMINO ACID ONTO THE FUNCTIONALIZED SOLID SUPPORT. CURRENT METHODS EITHER GIVE UNACCEPTABLE LOSS OF OPTICAL PURITY OR FAIL TO GIVE HIGH ENOUGH LEVELS OF… more
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