Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to develop novel hyperosmotic nanoemulsions for the prevention and treatment of infected wounds. Wound infections, whether acute or chronic, affects millions of Americans and have significant monetary and physiologic impacts on… more
Abstract:DESCRIPTION (provided by applicant): Inhibitors of Mycobacterial Protein Tyrosine Phosphatase B (mPTPB) for therapy of tuberculosis Aarden Pharmaceuticals Project Summary/Abstract The need exists for a new, breakthrough therapeutic for tuberculosis (TB). Current treatment regimens with toxic… more
Abstract:The Phase I program is directed at defining a buoy configuration that will capture the improved signal-to-noise ratios of surface or near-surface targets-of-interest when the acoustic sensor is located below the critical depth and as close to the ocean bottom as possible, capitalizing on the… more
Abstract:ABSTRACT: Improvements such as increased array size and better non-uniformity correction have been made to resistive emitter arrays fabricated on silicon (Si). There exist additonal wavelengths of interest whose emitter devices require fabrication in other materials, such as gallium arsenide (GaAs)… more
Abstract:Integrated Pest Management (IPM) is an ecological approach to managing insect pests in agricultural crops, which involves analyzing comprehensive information on the life cycles of pests, their interaction with the environment, past and current conditions of the crop field, etc., in order to provide… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a multi-modal sensor platform for robust detection and classification of insect pests for automated monitoring of insect populations. More specifically, the project will investigate the feasibility of extracting… more
Abstract:Cell-surface oligosaccharides appended to proteins and lipids are key binding epitopes in many critical biological processes, including bacterial infection, cell development and the immune response. Understanding these processes at the molecular level requires access to a wide range of … more
Abstract:The proposed project will focus on the development of closed loop frequency control hardware and algorithms for control of high quality factor tunable microwave filters based upon evanescent mode resonators. The developed controller will be modeled in Matlab to predict overall speed and stability.… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will produce technology to provide students with print disabilities (i.e., blindness, low vision, and learning disabilities that inhibit processing of text), who are commonly relegated to being passive observers in science classrooms,… more
Abstract:DESCRIPTION (provided by applicant): In recent years there has been increased interest throughout the world in the use of proton radiation therapy for treatment of cancer. Currently, there are only 9 operational centers in the US that treat a total of about 7,000 patients per year comprising less… more
Abstract:DESCRIPTION: PROJECT SUMMARY/ABSTRACT. This Phase II SBIR project, Game FACTS (Fun, Adaptable-Content Trainer Suite): The Use of Microgames as a Supplemental Learning Tool for Worker Health and Safety Training builds upon the work of the previously fundedPhase I SBIR project Micro-games for WMD… more
Abstract:DESCRIPTION (provided by applicant): Significance. In the United States, disproportionately high rates of sexually transmitted infection (STI) and unplanned pregnancy among adolescents suggest the continuing need for evidence-based sexuality education. Efforts to address sexual health through… more
Abstract:DESCRIPTION (provided by applicant): Advances in pharmaceutical drug development and the pioneering use of cell-cultures to produce biologic compounds have the potential to usher in a new era of medicine. There are incredible opportunities for developmentof drugs which are highly effective in… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost portable retinal camera, the DLP-Cam, in a community-based system for diabetic retinopathy (DR) screening and treatment. Untreated DRhas reached epidemic levels in underserved… more
Abstract:A small, efficient, light weight propulsion system consisting of a single cylinder, two cycle heavy fuel engine and a waterjet propulsor will be designed to meet the requirements for the 66 inch, 24 inch beam man-portable small Unmanned Surface Vehicle.
Abstract:Flow rate measurements for cryogenic propellants are required for spacecraft and space exploration systems. Such a requirement has been hampered by lack of fast and accurate instruments among existing technologies. This proposed project will develop a mass flow measurement system for… more
Abstract:ABSTRACT: This Small Business Innovation Research Phase 1 project will evaluate the feasibility of utilizing X-Ray tomography to map liquid mass fractions in optically dense sprays. High fuel flow rate nozzles are ubiquitous in rocket propulsion, power generation, and transportation. In these… more
Abstract:The focus of this project is on large-eddy simulation (LES) of high-speed turbulent reacting flows. The Enabling Energy Systems (EES) Inc. has assembled a well-experienced team of experts to tackle all the main issues involved in modeling of such complex flows. Several innovative ideas have been… more
Abstract:ABSTRACT: Increasing temperatures, combined with an accelerated demand for reducing weight in the engine, is creating new problems that require innovative solutions. As temperatures increase, oxidation and hot corrosion of compressor, combustor and turbine section components are becoming… more
Abstract:Pitting corrosion limits the lifetime and performance of turbine engine bearings and gears operated in marine environments. A number of alloys and improved treatments have been attempted to increase corrosion resistance while maintaining mechanical performance of the bearings, but few meet the… more
Abstract:This PHMSA SBIR focuses on the development of a new multi-channel cased in pipe design with internal support structure that will allow access along its entire axial length while adequately securing the carrier pipe to the containment pipe. When combined with the Seal Sensor System (proposed… more
Abstract:This PHMSA SBIR focuses on the development of a Pipe and Repair Sensor System. When combined with the Seal Sensor System (proposed separately), this technology will allow for a Smart Pipeline Network having integrated sensor networks that provide for continuous real-time monitoring of leaks and… more
Abstract:This PHMSA SBIR focuses on the development of a Seal Sensor System. When combined with the Pipe and Repair Sensor System (proposed separately), this technology will allow for a Smart Pipeline Network having integrated sensor networks that provide for continuous real-time monitoring of leaks and… more
Abstract:An opportunity to boost energy efficiency in homes and buildings exists through the design of functional radiative properties in glass and other building materials. Current surface materials ignore or take first-order approaches to complicated spectral behavior, leading to sub-optimal properties. … more
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