Abstract:Problems of large-scale nonlinear optimization are central to the solution of difficult and novel problems that arise from the need to distribute electric power in the most efficient and reliable way. In recognition of the importance of optimization in this area, DOE & apos;s Office of Advanced… more
Abstract:DESCRIPTION (provided by applicant): The ultimate goal of the proposal presented herein is to use E. coli as whole cell biocatalysts for the production of a wide variety of TDP-deoxysugars including di- and tri-deoxysugars, amino sugars and branched-chainsugars. These specialized activated hexoses… more
Abstract:DESCRIPTION (provided by applicant): Acoustic MedSystems proposes to develop an image-guided robot for MRI, CT and fluoroscopy guidance. The robot will be used for brain, prostate, liver, kidney, breast, and spine intervention. A general purpose robotic manipulator will be designed with development… more
Abstract:ABSTRACT: Designing efficient logic circuits involves improvement and optimization of transistors and interconnects. However, as technology follows Moore"s law down to nanometer dimensions, the performance gap between the transistors and interconnects is continuously widening. As conventional… more
Abstract:ABSTRACT: For navigation under GPS denied conditions, there is a need for developing inertial measurement units (IMU), employing gyroscopes and accelerometers, with better accuracy and/or smaller volume and weight than the state of the art. Currently, we at Digital Optics Technologies (DOT) have… more
Abstract:The overall goal of this project is to develop new tools and techniques to address current limitations in mobile forensics. Many factors, including
NAND Flash memory, passcode protected phones, encrypted data, lack of device support and simplistic analysis techniques in current forensic tools
Abstract:American Energy Technologies Co., a woman-owned small business concern of Illinois, will partner with Lockheed Martin MS2-Eagan, and with A.J. Drexel University, in order to develop and field an innovative manufacturing process for synthesis of highly conductive nanosized graphitic materials. A… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project addresses the challenge of coupling direct drive servo actuators to industrial robotic plants with uncertainties. Enhanced productivity sought in many applications requires higher cycle rates placing great demands on machine kinematics,… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop an ultra-thin high-R-value robust vacuum insulation panel (VIP). Thermal models indicate that with a half-inch thick VIP, an R-value of 40 can be achieved with an expected cost of ~$3 per square foot. The technology uses… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop and commercialize a new family of polymers (aromatic thermosetting copolyesters, or ATSP) for application to tribological surfaces for compressors used in air conditioning and refrigeration. Surface treatments/coatings are… more
Abstract:DESCRIPTION (provided by applicant): Methicillin resistant Staphylococcus aureus (MRSA) and methicillin sensitive S. aureus (MSSA) are highly significant human health threats that are responsible for a range of diseases. Recently, the CDC and colleagues reported that MRSA are the most significant… more
Abstract:DESCRIPTION (provided by applicant): Staphylococcus aureus is a significant human health threat, producing exotoxins called superantigens, which are responsible for a range of diseases. S. aureus superantigens are associated with food-borne illnesses, pulmonary disease, pneumonia, toxic shock… more
Abstract:DESCRIPTION (provided by applicant): Twenty-six million people in America have chronic kidney disease (CKD). Diabetes is by far the leading cause of CKD (diabetic nephropathy), accounting for 44% of new cases of dialysis (in 2005). Current treatments including ACE inhibitors for CKD patients mainly… more
Abstract:DESCRIPTION (provided by applicant): Twenty-six million people in America have chronic kidney disease (CKD). Despite the various treatments available to CKD patients, the five-year survival rate is ~33%. Inadequately controlled serum phosphate levels in CKD can lead to various pathologies of… more
Abstract:As a result of SBIR Phase I funding Global Feed in 3 & #8208;Dtm, allows users rapid and intuitive access to the data while simultaneously giving them the option of participating directly in the learning and analysis. The software integrates statistical analysis with tridimensional visualization… more
Abstract:CU Aerospace and team partner, the University of Illinois at Urbana-Champaign, propose to perform innovative research and development that targets the design and control of adaptive bioassistive and telerobotic devices - ABATRODs - that augment normal musculoskeletal function in rapidly changing and… more
Abstract:The primary objective of Phase I work performed by the team of CU Aerospace and the University of Illinois is to produce single-mode, high power (>1 W), narrow linewidth (<100 kHz), diode lasers with no mode hop for pumping alkali (Rb and Cs) atoms and verify their application to atomic… more
Abstract:Until early in the 20th century, nitrate fertilizer was manufactured by the electric arc process using water, air, and cheap hydroelectric power. Because this electric arc process was extremely inefficient, by the 1930s the process was replaced by the Haber-Bosch ammonia process which utilizes… more
Abstract:Current anaerobic digester systems are designed for capturing energy from waste from large heads of farm animals. GHD, Inc., a leading manufacturer of anaerobic digesters, has stated that a minimum dairy heard size for economical implementation of a biogas system as 800 cows. These require turbine… more
Abstract:DESCRIPTION (provided by applicant): This STTR project develops and assesses a new clinical test of visual contrast sensitivity that will work on infants and uninstructable children nd adults. This Stripe Card Contrast Sensitivity (SCCS) test would be useful in quantitatively describing the visual… more
Abstract:DESCRIPTION (provided by applicant): Application of nanotechnology in medicine, nanomedicine, has provided numerous emerging opportunities in healthcare, particularly given ever increasing demand for in vitro toxicology and diagnostics towards personalized medicine. With increasing demand… more
Abstract:This Small Business Innovation Research Phase I project aims at developing and commercializing a cost-effective cell injection system based on nanofountain probe (NFP) technology. The NFP has been recently used to investigate drug delivery and direct cell injection. Benefits of this method include… more
Abstract:DESCRIPTION (provided by applicant): ROS Technologies, Inc, is a medical diagnostics company developing a blood test to predict sudden death risk in patients with heart failure (HF). Heart failure affects more than five million Americans and increases therisk of sudden death. This application sets… more
Abstract:DESCRIPTION (provided by applicant): The clinical impact of the 5 million annual surveillance colonoscopies (follow up of previous neoplasia) is remarkably low (gt90% without significant neoplasia). Juxtaposed with this is the alarmingly frequent occurrence of colorectal cancers (CRCs) in… more
Abstract:This Small Business Innovation Research Phase I project aims to develop and commercialize a technology that can screen patients who are at risk for lung cancer by means of a simple buccal swab of the cheek epithelium. Lung cancer is the leading cause of cancer deaths in the U.S. The reason for the… more
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