Abstract:Etrema is developing an acoustic projector that provides broad bandwidth, high source level, directional output, high duty cycle, and high reliability in a compact package. Specific objectives of the Phase II effort are: demonstrate performance of a prototype projector, optimize the full-scale… more
Abstract:DESCRIPTION (provided by applicant): Project Summary/Abstract Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by mutations in the DMD gene with a prevalence of 1 in 3500 male births. The consequent loss of functional dystrophin results in the progressive degeneration… more
Abstract:DESCRIPTION (provided by applicant): Ataxia-Telangiectasia (A-T) is a multi-systemic, recessively inherited disorder characterized primarily by early onset cerebellar ataxia and telangiectasia, from which the disease name is derived. In addition, patientsalso exhibit a number of other clinical… more
Abstract:DESCRIPTION (provided by applicant): Atherosclerosis is the primary cause of cardiovascular disease, which is the most common cause of death in the United States. Atherosclerosis is characterized by the accumulation of lipids, cholesterol, calcium deposits, and cellular debris in vessel walls, and… more
Abstract:Currently there are no truly effective interventions or therapeutic treatments for White spot syndrome virus (WSSV) in farmed shrimp. Current production practices focus on pathogen exclusion by stocking specific pathogen free (SPF) larvae, decontamination and filtration of water to prevent pathogen… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project is about developing an Educational Interactive Hemodynamics Flow Visualization and Analysis System to be used in physiology courses for anyone studying blood flows such as medical or bioengineering students. Study of hemodynamics is very… more
Abstract:The incorporation of viscous analysis in design is vital for a completeunderstanding of aerodynamic problems.This proposal offers to develop and integrate with RotCFD a method for semi-automatically generating grids suitable for viscous
analysis on complex configurations as well as parallelize the… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to use nitrocarburizing plasmas to generate nanostructured layer on top of nitride case on cast iron surfaces of cast iron dies used in the stamping of high-strength-steel sheets. To deposit nanostructured coatings, reactive… more
Abstract:DESCRIPTION (provided by applicant): In approximately 30% of epileptic patients, seizures are not controlled by currently available therapeutic agents. Even though a number of new chemical entities have entered the marketplace, therapy resistant seizures remain. This project is innovative in that… more
Abstract:The aerodynamic performance of aircraft is significantly impacted by the aero-elastic dynamics of its control surfaces. In particular, the dynamics of flutter - an unstable self-excitation of structure due to undesirable coupling of structural flexibility and aerodynamics - has critical impact on… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will test the baseline requirements necessary for the development of an employee performance measurement platform that utilizes technology to accomplish a continuous service performance data flow used to motivate employees to higher… more
Abstract:The Smart Grid opens the door to the development of many companion devices which will in turn enable the development of a variety of devices for household electricity-consuming appliances that can communicate with it; especially, many major appliance manufacturers (such as Whirlpool and General… more
Abstract:DESCRIPTION (provided by applicant): Drugs used for cancer chemotherapy tend to be highly cytotoxic and genotoxic, with well-documented carcinogenic, mutagenic, and teratogenic effects. Long-term, occupational exposure to these highly toxic drugs presents
serious health risks to the healthcare… more
Abstract:This SBIR Phase I project will develop the feasibility of using piezoelectric transducers to create an artificial plant, embodied as tall bunchgrass, that will harvest and store energy from wind. This device will have aesthetic appeal and provide a nonpolluting supplement to energy produced by wind… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to demonstrate a unique and affordable method to nanotexture the surfaces of metal platform drug-eluting stents (DES) using ultrafast laser surface modification. This technology is relatively inexpensive and capable of integrating… more
Abstract:The SKATE concept was designed to quantify skill levels of trainees, teams, or units, generate skill-appropriate training scenarios, and provide a continuous skill-level assessment of disparately skilled trainees, teams, and units in a joint training exercise while maintaining the overall integrity… more
Abstract:This proposal describes an approach to realize InAs/GaSb type II superlattice focal plane arrays through planar processing. A problem with conventional mesa diode processing approaches is that nonradiative surface recombination at the exposed pn junction is extremely rapid, leading to surface… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a compact, widely-tunable, high-brightness laser diode spectrometer that will be the core of an automated point-of-care (POC) monitor capable of tracking key blood metabolites for patients in intensive care units. The… more
Abstract:DESCRIPTION (provided by applicant): Indigenous population, travelers and troops present in Africa and South America are clearly at risk of exposure to several arenaviruses. Several human pathogenic arenaviruses, e.g., Lassa and Junin viruses, are listed o
n the NIAID's Priority Pathogens and CDC's… more
Abstract:Determining meat quality attributes in food animals is essential for genetic selection, sorting, and marketing. Ultrasound techniques have the potential to benefit the swine industry for improvements in both quality and yield measures by non-destructive and non-invasive means. Biotronics, Inc. has… more
Abstract:This Small Business Technology Transfer (STTR) Phase II project will develop an assistive software tool for endoscopists to have real-time feedback of objective quality for colon and potential polyp region examinations. The technology is aimed to reduce polyp miss rates during colonoscopy.… more
Abstract:Energy harvesting devices utilizing magnetostrictive materials are a logical choice for harvesting the high impedance (high force, low displacement) vibrations found aboard Navy ships. Force-based devices, enabled by magnetostrictive materials, can harvest energy over an extremely large bandwidth,… more
Abstract:DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene encodes a chloride channel that regulates ion flow across epithelial cell membranes. Most
CF patients have a mutation that deletes… more
Abstract:DESCRIPTION (provided by applicant): Atherosclerosis is the primary cause of cardiovascular disease, which is the most common cause of death in the United States. Atherosclerosis is characterized by the accumulation of lipids, cholesterol, calcium deposi
ts, and cellular debris in vessel walls,… more
Abstract:The current state of the art of soybean processing requires heat processing to eliminate anti-nutrition factors and make the protein available for digestion. The proposed research will investigate the opportunity to process a new soybean variety that has been traditionally bred (not genetically… more
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