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Displaying 551 – 575 of 630 Awards
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: N/A
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: N/A
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE OVERALL GOAL OF THIS PROJECT IS TO DEVELOP IMMUNOASSAYS CAPABLE OF DETECTING DIDEMNINS AT THE NANOGRAM LEVEL. DIDEMNIN B IS THE MOST POTENT ANTITUMOR, ANTIVIRAL, AND CYTOTOXIC MEMBER OF A FAMILY OF FIVE CYCLIC DEPSIPEPTIDES ISOLATED FROM MARINE TUNICATES. THIS COMPOUND IS CURRENTLY IN CLINICAL… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: NSF / SBIR / 1989 / 1
Abstract: IMMUNOCHEMICAL TECHNIQUES HAVE MANY DIVERSE APPLICATIONS. HOWEVER, THEY ARE RESTRICTED TO USE ONLY IN AQUEOUS MEDIA. ECONOMICAL TECHNIQUES FOR DIRECT ORGANIC PHASE ANALYSIS AND IMMUNOAFFINITY ISOLATION WOULD SIGNIFICANTLY BROADEN THE USEFULNESS OF ANTIBODY-BASED TECHNOLOGY. THE PURPOSE OF THIS… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: NSF / SBIR / 1989 / 1
Abstract: THE PROPOSED RESEARCH WILL INVESTIGATE THE ABILITY OF NEUROSPORA CRASSA TO EXPRESS AND SECRETE BIOLOGICALLY-ACTIVEMAMMALIAN PROTEINS. THE ABILITY TO GENETICALLY ENGINEER BACTERIA AND YEASTS FOR THESE TASKS IS WELL DOCUMENTED. HOWEVER, RECOMBINANT PRODUCTS FROM THESE ORGANISMS OFTEN REQUIRE COSTLY… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: N/A
Company: Moana Bioproducts Inc Agency/Program/Year/Phase: DOC / SBIR / 1989 / 1
Abstract: THIS PROPOSAL DESCRIBES A UNIQUE AND HIGHLY SIMPLIFIED IMMUNOLOGICAL PROCEDURE USING A MONOCLONAL ANTIBODY TO CIGUATOXIN IN A TWO-STEP PROCEDURE. THE MONOCLONAL ANTIBODY(MAB) IS PREPARED BY THE MOUSE HYBRIDOMA TECHNIQUE, USING HIGHLY PURIFIED CIGUATOXIN CONJUGATED TO PROTEIN CARRIERS. THE MAB-CTX… more
Company: Multipath Systems, Inc Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: THE PROPOSED ULTRASONIC SPATIAL SENSING AID FOR THE BLIND IS AN ELECTRONIC TRAVEL AID DESIGNED TO PROVIDE THE BLIND TRAVELER WITH SPATIAL CONTEXTUAL INFORMATION, A NECESSARY PREREQUISITE FOR MOBILITY. THE DEVICE OPERATES ON THE ECHOLOCATING PRINCIPLE, BY BROADCASTING ULTRASOUND WHICH IS REFLECTED BY… more
Company: Sets Technology Inc Agency/Program/Year/Phase: DOD / SBIR / 1989 / 2
Abstract: THIS PROPOSAL RESPONDS TO DOD TECHNICAL SUBTOPIC A88-162: HYPERSPECTRAL/IMAGE EXPLOITATION, WHICH REQUEST THE DESIGN AND IMPLEMENTATION OF SOFTWARE FOR HYPERSPECTRAL IMAGE EXPLOITATION. THE RESULT WOULD BE THE DEVELOPMENT OF A INTEGRATED SYSTEM WHICH WOULD ALLOW THE ARMY TO EVALUATE THE POTENTIAL… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: TECHNICAL RESEARCH ASSOCIATES, INC. PROPOSES THE DEVELOPMENTOF A NOVEL PLATELET-HARVESTING SYSTEM BASED ON A PREVIOUSLY DEVELOPED ULTRASOUND SEPARATION TECHNOLOGY. THIS TECHNOLOGY, DEVELOPED UNDER AN NHLBI GRANT, ALLOWS THE SEQUENTIAL SEPARATION OF CELLS BASED ON THEIR SIZE, EVEN THOSE CELLS THAT… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 2
Abstract: IN ORDER TO USE THE NEW CERAMIC SUPERCONDUCTOR MATERIALS IN MANY APPLICATIONS, THE NORMALLY BRITTLE MATERIALS MUST BE FORMED INTO WIRES. THIS PROPOSAL SUGGESTS A WET CHEMISTRY TECHNIQUE FOR FORMING THE SUPERCONDUCTOR COMPOUND INTO A WIRE, WHICH WILL THEN BE COATED WITH A METAL JACKET TO PROTECT THE… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE OVERALL OBJECTIVE OF THIS PROJECT IS TO DESIGN AN APPARATUS AND PROCEDURE TO EXTEND THE VITALITY OF STORED HUMAN PLATELET CONCENTRATES FOR TRANSFUSION. EXPERIMENTS WILL BE CONDUCTED THAT WILL SIMULATE THE CONDITION OF MICROGRAVITY STORAGE AND AT THE SAME TIME KEEP MOST OF THE PLATELETS AWAY FROM… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: NSF / SBIR / 1989 / 1
Abstract: POLAR EXPLORATION AND STUDY OF THE POLAR WORLD HAVE BROUGHT ABOUT THE NECESSITY FOR HOUSING ENGINEERS AND SCIENTISTS WHO PRODUCE LIQUID AND SOLID WASTES THAT MUST BE DISPOSED OFIN WHAT CONSTITUTES A HOSTILE ENVIRONMENT. THIS STUDY DEALSWITH SELECTING WASTE WATER TECHNIQUES WHICH WHEN OPERATING… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THIS PROJECT WILL DEVELOP A UNIQUE ANIMAL IDENTIFICATION SYSTEM CONSISTING OF A PASSIVE IMPLANTABLE AND A HAND-HELD ACTIVE SENSOR DEVICE. PHASE I DEVELOPMENT WILL FOCUS ON AN INITIAL INVESTIGATION OF THE IMPLANTABLE'S CHARACTERISTICS WITH A SECONDARY EFFORT TO DESIGN THE SENSOR CIRCUITRY. SMALL RATS… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOE / SBIR / 1989 / 1
Abstract: N/A
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 2
Abstract: THE ULTIMATE OBJECTIVE OF THIS PROJECT IS THE PRODUCTION OF A DENGUE VACCINE. THE FOUR DENGUE VIRUSES (SEROTYPES) AS A GROUP ARE BY FAR THE MOST IMPORTANT VIRUSES TRANSMITTED TO MAN BY ARTHROPODS AND IN TERMS OF GLOBAL MORBIDITY ARE RESPONSIBLE FOR SEVERAL HUNDRED THOUSAND TO SEVERAL MILLION CASES… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 2
Abstract: TETRODOTOXIN IS A HIGHLY POTENT LOW MOLECULAR WEIGHT NEUROTOXIN FOUND IN SOME SPECIES OF PUFFERFISH AND A FEW OTHER WIDELY DIVERGENT ORGANISMS. CURRENTLY, TETRODOTOXIN IS MEASURED BY MOUSE BIOASSAY OR WITH SOPHISTICATED CHROMATOGRAPHIC METHODS. A SIMPLE, SPECIFIC, EASY TO USE ASSAY METHOD FOR… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE OVERALL GOAL OF THIS PROJECT IS TO DEVELOP IMMUNOASSAYS CAPABLE OF DETECTING AVAROL AND AVARONE AT THE NANOGRAM LEVEL IN BIOLOGICAL SAMPLES. AVAROL IS A MARINE NATURAL PRODUCT WITH POTENT ANTI-TUMOR AND ANTI-AIDS ACTIVITY. THISCOMPOUND IS UNDERGOING EVALUATION AS AN ANTI-AIDS DRUG AND AN… more
Company: Multipath Systems, Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Sensors Hawaii Inc Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: THE NOVEL MULTI-DIMENSION RESOLVING ACCELEROMETER IS A UNIQUE INERTIAL MEASURING DEVICE DESIGNED TO PROVIDE CARTESIAN COMPONENTS OF APPLIED ACCELERATION. THE DEVICE OPERATION IS AN INNOVATIVE UTILIZATION OF SEMICONDUCTOR TECHNOLOGY COUPLED WITH STRUCTURAL MECHANICS. THE OBJECTIVES OF THIS PROPOSAL… more
Company: Sets Technology Inc Agency/Program/Year/Phase: NASA / SBIR / 1988 / 2
Abstract: THIS PROPOSAL RESPONDS TO TECHNICAL SUBTOPIC 08.27: MULTI-CHANNEL INFRARED SPECTROMETER, WHICH REQUESTED A SPECTROMETER BE DEVELOPED CAPABLE OF SAMPLING SIMULTANEOUSLYTHE SPECTRAL RANGE 1.0 TO 2.5 AT 1% RESOLUTION WITH A NEP OF 10-16 W/HZ. THE OPPORTUNITY IS TO APPLY NEW IR ARRAY DETECTORS AND… more
Company: Sets Technology Inc Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: N/A
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 2
Abstract: A FOUR-ELEMENT FEASIBILITY STUDY IS PROPOSED TO EVALUATE A NOVEL IDEA FOR PROVIDING URINARY BLADDER CONTINENCE TO INCONTINENT INDIVIDUALS, ESPECIALLY THE AGED. THE DEVICE IS A NONSURGICALLY INSERTED FLEXIBLE SEAL. MICTURITION CAN BE INITIATED BY AN EXTERNAL SEAL CONTROLLER. BECAUSE THE DEVICE CAN BE… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: NSF / SBIR / 1988 / 2
Abstract: TITANIUM HYDRIDE REACTION WITH AMMONIA IN THE PRESENCE OF A NICKEL CATALYST TO FORM TITANIUM NITRIDE SHOWS UNEXPECTED KINETIC BEHANVIOR. A FUNDAMENTAL STUDY TO DETERMINE IF THE CAUSE OF THIS BEHAVIOR IS RELATED TO TITANIUM PHASE CHANGES IS PROPOSED. THE EFFECTS OF NITROGEN CONTENT ON WETTING OF TIN… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOE / SBIR / 1988 / 2
Abstract: THE FIRST WALL STRUCTURE OF FUSION REACTORS WILL BE EXPOSED TO HOT PLASMAS AND HIGH HEAT FLUXES. THIS RESEARCH WILL DETERMINE THE FEASIBILITY OF USING BIDIRECTIONAL GRAPHITE REINFORCEMENT IN COPPER ALLOYS TO PROVIDE A TRANSITION BETWEEN CERAMIC ARMOR (WHICH PROVIDES RESISTANCE TO THE PLASMA… more
Displaying 551 – 575 of 630 Awards
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