Abstract:In this proposal, AlphaSense, Inc. (AI) and the University of Michigan (UM) detail the development of a novel automated and controlled dual laser ablation system for selective chrome removal. The key innovations of this proposal include the following: a) The combination of ns- and fs- laser ablation… more
Abstract:In this proposal, AlphaSense, Inc. details the development of a novel sensor for pitting corrosion monitoring and load distribution measurements. The key innovations of this proposal include the following: a) corrosion and load distribution measurements based on the electrical impedance measurements… more
Abstract:In the current SBIR program, AlphaSense aimed at developing a novel, handheld, non-destructive sensor to evaluate the integrity of Naval Advanced Amorphous Coatings (NAAC) in real time. In phase I, we have proven the feasibility of using the cavity perturbation technique to detect different types of… more
Abstract:DESCRIPTION (provided by applicant): Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of diseases and in situ evaluation of living tissues. However, the application of Raman spectroscopy for tissue evaluation has been limited by the strong tissue fluorescence that… more
Abstract:DESCRIPTION (provided by applicant): Transition metal catalysts are widely used in the pharmaceutical industry for the production of active ingredients, precursors and new drug candidates. These products must be very pure, often requiring labor and energyintensive separation processes, to achieve… more
Abstract:DESCRIPTION (provided by applicant): The overall focus of this application is to develop nanofiltration membranes to recover the spent solvents generated from drug manufacturing processes allowing the solvents to be reused resulting in elimination of waste. This is also responsive to NIH RFP… more
Abstract:DESCRIPTION (provided by applicant): Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds Project Summary: In the chemical manufacturing of pharmaceutical compounds, organic syntheses are often carried out in organic solvents and involve intermediates and final products with high… more
Abstract:DESCRIPTION (provided by applicant): The commercial syntheses of many pharmaceutical active ingredients and intermediates require acid catalysts and the removal of water to drive reactions to completion. Typical reactions include esterifications of carboxylic acids with alcohols, Friedel-Crafts… more
Abstract:DESCRIPTION (provided by applicant): Compact Membrane Systems (CMS) proposes to develop a perfluoro membrane reactor technology that will provide a generally applicable tool for removing water and oxygen from pharmaceutical synthesis processes. This innovation aims to improve product quality and… more
Abstract:Fossil fuels currently supply more than 85% of the worlds energy needs with the ensuing generation of 80% of all anthropogenic emissions of carbon dioxide. Carbon dioxide as a greenhouse gas is considered to be a major contributor to global warming. There is a concerted effort towards capturing… more
Abstract:Industrial hydrogen production relies primarily on natural gas and hydrocarbon feedstocks to drive the various reaction chemistries that lead to hydrogen generation. Carbon dioxide, the ultimate co-product when such feedstocks and processes are employed, necessarily becomes a major contaminant of… more
Abstract:Ethylene and propylene are major chemical industry raw materials and consume a great deal of energy related to their production. It is estimated that 230 trillion BTU/yr are consumed in olefin/paraffin separations. Significant energy consumption is employed when cryogenically separating ethane from… more
Abstract:Solvent extraction by hexane is the most common choice for extraction of oil/lipids from algae. However, hexane is not the best choice of solvent for algae oil extraction because of the need to market byproducts for human and animal consumption. Oil and hexane from the solvent extraction process are… more
Abstract:Vapors produced during the process of refueling cars are a significant source of Volatile Organic Compounds (VOCs) emissions. Uncontrolled emissions cause economic losses and pollute the environment. This problem is exacerbated when the gasoline contains bioethanol because its presence increases the… more
Abstract:Soybean is the major source for production of edible oils worldwide and in United States. Pressing of the soybean into flakes followed by the solvent extraction with hexane (solvent) is most widely practiced for extraction of oil. Separation of solvent from oil-solvent mixture for solvent recovery… more
Abstract:At the heart of scientific computing and numerical analysis are linear algebra solvers. In scientific computing, the focus is on the partial differential equations (PDEs) that arise from computational fluid dynamics (CFD), climate modeling, astrophysics, and structural and heat analysis that cannot… more
Abstract:In an attempt to build more computationally powerful systems and improve the FLOPS/dollar and FLOPS/Watt of high-performance computers (HPCs), we have recently seen the proliferation of GPU-based clusters. Many major vendors are now supporting this technology and such systems are becoming… more
Abstract:Space-based imaging sensors are important for NASA's mission in both performing scientific measurements and producing literature and documentary cinema. The recent proliferation of high-definition capture devices and displays (HDTV) provide the general public with first-hand human experiences… more
Abstract:ABSTRACT: We propose to apply modern massively multicore processors to a key problem area of interest to the Air Force: multiphysics computational fluid dynamics (CFD) and computational structural dynamics (CSD) solvers. The capabilities of the CPU to solve these problems have been increasing… more
Abstract:ABSTRACT: Crystalline semiconductor nanomembranes (NMs) possess the electronic/photonic properties of bulk material, although they are flexible, deformable, and conformable. Semiconductor nanomembranes offer unique opportunities for novel active/ passive electronic, and photonic devices suitable… more
Abstract:ABSTRACT: Optical interconnects are the natural choice for interconnecting different chips when current interconnect technologies cannot fulfill current and future system requirements. Examples of optical interconnect architectures are free-space multistage interconnect, optical fiber interconnect,… more
Abstract:A novel high performance, lightweight vehicle armor system for the Expeditionary Fighting Vehicle (EFV) is proposed. Following past work with perforated metals for weight efficient armor, the present work examines ceramic-based armor systems where the ceramic component has a novel design (e.g.,… more
Abstract:The Army is in need of an improved material for use in bridge structures. Key requirements are reduced weight relative to current metallic structures (steel and aluminum), high strength, resistance to catastrophic failure, attractive cost, and resistance to environmental factors (weather, corrosion… more
Abstract:To meet the ever-increasing challenges imposed by next generation weapon systems and continued reduced manning efforts, Quantum Leap Innovations, Inc. will collaborate with the Institute for Simulation and Training (IST) at the University of Central Florida (UCF) to develop adaptive, embeddable, and… more
Abstract:Existing Anti-Submarine Warfare (ASW) mission planners can specify patrol regions for available sensor platforms and provide detailed, coordinated search tracks for each platform. However, most of the planners have not considered any real-time sensor information feedback during optimization and… more
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