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Company: NEUGENESIS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE ESSENTIAL PLAN OF THIS PROPOSAL IS TO USE OOCYTE MICROINJECTION TO CREATE STRAINS OF MICE THAT ARE TOLERANT TO THE SPECIES-SPECIFIC DETERMINANTS THAT DISTINGUISH HUMAN CLASS I, DR, DC, OR SB ANTIGENS AS A GROUP FROM THEIR MURINE ANALOGUES INDEPENDENT OF THEIR ALLELIC VARIATIONS. THESE STRAINS OF… more
Company: Guyer Santin, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1985 / 1
Abstract: MANAGMENT OF GROUND WATER IS MORE EMPIRICAL ART THAN SCIENCE, MUCH OF WHICH HAS BEEN DEVELOPED IN THE BRICK AND MORTAR INDUSTRIES OF MINING, TUNNELING, DAM AND POWER PLANT DESIGN. THIS PROPOSAL IS TO RESEARCH AND DOCUMENT THE STATE OF THE ART IN THE U.S. AND ABROAD, IDENTIFY METHODS HAVING POTENTIAL… more
Company: Guyer Santin, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1985 / 1
Abstract: GROUTING IS USED AS A REPAIR METHOD IN DAMS, POWERPLANTS, TUNNELS AND SIMILAR STRUCTURES SUBJECT TO GROUND WATER PRESSURE. IN THESE APPLICATIONS SPEED HAS NOT BEEN IMPORTANT BECAUSE IT IS USED IN RESPONSE TO DAMAGE DUE TO LONG TIMEFRAME DISRUPTIONS SUCH AS SOIL CONSOLIDATION, MINOR SEISMIC ACTIVITY,… more
Company: Hemascience Laboratorytorie Agency/Program/Year/Phase: HHS / SBIR / 1985 / 2
Abstract: DEMANDS FOR WASHED RED BLOOD CELLS IS INCREASING. THIS IS IN PART TO AWARENESS OF TRANSFUSION RELATED DISEASE SUCH AS HEPATITIS AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS). EXISTING TECHNOLOGY FOR CELL WASHING IS INEFFICIENT IN THAT A SIGNIFICANT AMOUNT OF FINAL WASHED PRODUCT IS OFTEN LOST IN… more
Company: Hokenson Co Agency/Program/Year/Phase: DOD / SBIR / 1985 / 1
Abstract: A TWO-DECK BOUNDARY LAYER MODEL OF THE FLOW OVER AN ABLATING (AND/OR TRANSPIRING) SURFACE IS PROPOSED IN ORDER TO COMPUTE THE SURFACE ROUGHNESS AND TEMPERATURE DISTRIBUTION IN THE WALL AND FLOW FOR A GIVEN SET OF WALL AND FREESTREAM CONDITIONS. THE OUTER FLOW OF THE TWO-DECK MODEL RESEMBLES A… more
Company: Homogenetics Inc. Agency/Program/Year/Phase: USDA / SBIR / 1985 / 1
Abstract: A RAPID AND VERY SENSITIVE BIOLUMINESCENT IMMUNOASSAY WILL BE USED FOR TRHE DETECTION AND MEASUREMENT OF SALMONELLA BACTERIA IN FOODS. BOTH POLYCOLONAL AND MONOCLONAL ANTIBODIES TO SALMONELLA WILL BE USED. IT IS HOPED TO ATTAINDETECTION LIMITS OF A FEW HUNDRED BACTERIA PER ML. IN AN ASSAY TAKING… more
Company: Howard-schlumberger Agency/Program/Year/Phase: DOD / SBIR / 1985 / 1
Abstract: A NEW METHOD FOR RECONSTRUCTING IMAGES FROM INFORMATION OBTAINED USING A VERY DIFFERENT TRANSMITTER AND RECEIVER CONFIGURATION HAS BEEN DEVELOPED. SENSORS (TRANSMITTER AND RECEIVERS) ARE DEPLOYED OR SCANNED ALONG SKEWED NON-INTERSECTING LINES; THAT IS, COVERING OR SCANNING OVER AN AREA IS NOT… more
Company: Human Performance Research Agency/Program/Year/Phase: DOD / SBIR / 1985 / 2
Abstract: THE PROPOSED STUDY IS INTENDED TO IDENTIFY THE COMMUNICATION REQUIREMENTS FOR COMBAT OPERATIONS ON USN SURFACE COMBATANTS, AND APPLY THE LASTEST TECHNOLOGIES AVAILABLE IN THE COMMUNICATION INDUSTRY TO DEVELOP DESIGN RECOMMENDATIONS FOR VOICE, DIGITIZED VOICE, AND DISPLAY SYSTEMS, TO REQUIRED, AS… more
Company: IDEC PHARMACEUTICALS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Idetek, Inc. Agency/Program/Year/Phase: USDA / SBIR / 1985 / 1
Abstract: THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A SIMPLIFIED, N NON-INSTRUMENTED IMMUNOASSAY SYSTEM FOR THE DETECTION OF AFLATOXIN B1 IN AGRICULTURAL COMMODITIES. THIS SYSTEM WILL BE SUITABLE FOR FIELD MONITORING AND, WHERE APPROPRIATE, BLENDING OF PRODUCT. VISUALLY READABLE STANDARDS WILL BE DEVELOPED… more
Company: Inet Corp Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE OBJECTIVE OF THIS PROJECT IS TO STUDY THE FEASIBILITY OF CONVERTING THE NATIONAL CANCER INSTITUTE DRUG INFORMATION SYSTEM (DIS) SOFTWARE FROM DEC-10 COMPUTER TO A 32-BIT COMPUTER ENVIRONMENT. 2.SOFTWARE REQUIREMENTS OF THE TARGET MACHINE. 3.RECOMMENDED SELECTION OF THE TARGET MACHINE. 4… more
Company: Integrated Systems I Agency/Program/Year/Phase: NASA / SBIR / 1985 / 1
Abstract: REAL-TIME FLUTTER PREDICTION INCLUDING CLOSE MODES CAN BE EFFECTIVELY ESTIMATED FROM TURBULENCE OR ON-BOARD EXCITATIONWITH AN EXTENDED KALMAN FILTER(EKF) APPROACH. THE THE PHYSICALLY BASED MODEL FORM ENABLES PREDICTION OF THE DAMPING RATE AS WELL AS DAMPING GIVING A TIME TO UNSTABILITYESTIMATE WITH… more
Company: Intek Diagnostics Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THERE ARE NO SENSITIVE METHODS FOR THE DIAGNOSIS OF METASTASES AND LYMPH NODE INVOLVEMENT IN HUMAN SQUAMOUS CELL CARCINOMA (SCC) OF THE HEAD AND NECK REGION. RADIOIMMUNODETECTION IS CAPABLE OF HIGH RESOLUTION AND SENSITIVITY IN LOCATING TUMORS. THE LONG-TERM GOAL OF THIS RESEARCH PROPOSAL IS THE… more
Company: Intek Diagnostics Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: INTEK DIAGNOSTICS, INC. (FORMERLY CARCINEX, INC.) IS A SMALL BUSINESS CORPORATION FUNDED TO DEVELOP AND MARKET NEW METHODS TO DIAGNOSE, STAGE, AND TREAT SQUAMOUS CELL CARCINOMAS. INTEK DIAGNOSTICS HAS DEVELOPED A LIBRARY OF HIGHLY TUMOR-ASSOCIATED MURINE MONOCLONAL ANTIBODIES. THESE ANTIBODIES REACT… more
Company: Intek Diagnostics Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: INTEK HAS DEVELOPED OVER 20 VERY PROMISING TUMOR-ASSOCIATED AND POSSIBLY TUMOR-SPECIFIC MURINE MONOCLONAL ANTIBODIES AGAINST SQUAMOUS CELL CARCINOMA (SCC) TUMORS. THERE ARE CURRENTLY NO IMMUNOLOGICAL METHODS IN USE FOR MONITORING SCC PATIENTS FOR RECURRENCE OF TUMOR, OR FOR IDENTIFICATION OF… more
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