Abstract:Increasing electrification of the modern military ground vehicle fleet places ever-increasing demand on each vehicle"s electric power generation and distribution systems. The quantity of instrumentation, computing, and electronic weaponry countermeasures systems is rapidly growing, as is their… more
Abstract:DESCRIPTION (provided by applicant): A binary probe-based DNAzyme cascade for rapid detection of MRSA/MSSA Project Summary This STTR Phase I project will develop a proof-of-concept molecular test for rapid detection of Staphylococcus aureus (SA) and differentiation between methicillin-resistant SA… more
Abstract:DESCRIPTION (provided by applicant): This SBIR project is a collaborative effort between AC Diagnostics, Inc. and the University of Pennsylvania to develop and demonstrate a novel diagnostic system for automated on-site detection of viral pathogens in biomedical laboratory animals. Microbial… more
Abstract:DESCRIPTION (provided by applicant): Wheelchairs in the modern form have been around since at least 1760, when John Joseph Merlin invented pushrim propulsion. Manual wheelchairs are preferred by diagnosing physicians as the act of propulsion provides important cardiovascular exercise for the user.… more
Abstract:Biomass to biofuels can provide solutions for energy independence, lower cost of fuels and global climate change mitigation. However, to achieve the goal of converting biomass into biofuels, the biomass must be broken down into its component sugars so they can be fermented into fuels. Cellulases are… more
Abstract:DESCRIPTION (provided by applicant): There is an urgent need for speech generating devices (SGDs) designed for young children with complex communication needs. Available SGDs are difficult for children to use and time consuming for adults to program. Without appropriate SGDs, children miss valuable… more
Abstract:DESCRIPTION (provided by applicant): Speech generating devices (SGDs) offer people with difficult to understand speech (dysarthria) a synthesized speech replacement for their natural speech. However, people who require SGDs often prefer using their natural speech because it is perceived as normal… more
Abstract:DESCRIPTION (provided by applicant): We develop an integrated writing method named GWP that seamlessly switches between typing, word prediction, and predictive gesturing. Predictive gesturing enables a person to enter text by moving the mouse cursor toward a few letters in a word without requiring… more
Abstract:DESCRIPTION (provided by applicant): Chest pain in patients presenting to the emergency department (ED) present a clinical dilemma: transfer for emergent coronary revascularization, admit overnight for cardiac telemetry and stress testing, or discharge home with medical follow-up. In this proposal,… more
Abstract:Breast cancer is the most common type of cancer and the second leading cause of cancer death among women with more than one million new cases and 370,000 deaths worldwide yearly. Chemotherapy drugs, such as Doxorubicin, have been used in both pre- and post-operative adjuvant therapy or as the main… more
Abstract:The goal of this project is to develop multiple-biomarker imaging for detection of human papillomavirus (HPV) associated human cancer. Quantum dots (QDs) with multiple emission colors were chosen as optical probes to label the biomarkers on tissue. Attribute to the unique optical properties of… more
Abstract:Our goal is to develop easy1to use, inexpensive, and sensitive quantum dots(QDs) or quantum dots nano beads (QDnBs or QDBs) based rapid diagnostic strip test for folate and surrogate metabolites (homocysteine and methylmalonate) in a multiplex assay using quantum dots/quantum dots nano beads based… more
Abstract:This effort seeks to build upon our successful Phase I effort to utilize, refine, and perform detailed testing on designs utilizing our EM Emanation Reduction (EMER) technique for FPGAs. The EMER technique is designed to reduce the feasibility of side-channel attacks aimed at gaining critical… more
Abstract:The Federal Railroad Administration’s (FRA) Automated Track Inspection Program uses optical systems such as cameras or laser-based systems to monitor rail performance throughout the country. These systems are hindered by adverse weather conditions that allow water, dirt and mud to coat their… more
Abstract:According to the NASA A2.01 topic description titled Materials and Structures for Future Aircraft, "advanced materials and structures technologies are needed in all four of the NASA Fundamental Aeronautics Program research thrusts (Subsonics Fixed Wing, Subsonics Rotary Wing, Supersonics, and… more
Abstract:There is a continual drive to move electronics out of the "warm box" to their point of use on space platforms. This requires electronics that can operate reliably over a wide range of temperatures and in the presence of radiation. The range of functions needed at various points across a… more
Abstract:Global electricity from wind power will reach 12 percent by 2050, requiring 3.2 trillion dollars to be invested over the next 40 years. In 2009, wind power additions in the United States were valued at 21 billion dollars, reaching nearly 10GW of new capacity. Despite the financial crisis in 2009 and… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will explore the synthesis and use of novel lignin-derived carbon-magnetite nanocomposites for removal of aqueous phosphate– a run off pollutant from agricultural farms that leads to eutrophication of lakes and other water reservoirs. … more
Abstract:DESCRIPTION (provided by applicant): Acetaminophen (APAP) is the most commonly used drug for the treatment of pain and fever in the world today. In large doses, APAP causes acute liver failure and is the leading cause of acute liver failure in the US. Thecurrent laboratory test for the diagnosis of… more
Abstract:The objective of this proposal is to develop new techniques for addressing the engineering change requests (202"s). These techniques include new processes and workflow management techniques designed to streamline the process and minimize the response time. The 202 process is essentially a… more
Abstract:In this SBIR project, APEI, Inc. is proposing to develop a high efficiency, rad-hard 3.8 kW silicon carbide (SiC) power supply for the Power Processing Unit (PPU) of Hall Effect thrusters. This program specifically targets the design of a PPU for the HiVHAC (High Voltage Hall ACcelerator) thruster,… more
Abstract:In this SBIR project, APEI, Inc. is proposing to develop a high efficiency, rad-hard, 100's kWe power management and distribution (PMAD) system for space nuclear power systems. The PMAD will utilize SiC JFET power switches; components which APEI, Inc. has irradiated under TID conditions to… more
Abstract:In this SBIR effort, Arkansas Power Electronics International, Inc. (APEI, Inc.) and the University of Arkansas are partnering to develop a versatile, radiation-hardened, low-power, asynchronous 8051-based microcontroller capable of functioning in a very wide temperature range… more
Abstract:In this program, APEI, Inc. will build on successful demonstrations of SiC-based wireless transmitter designs in high temperature and high mechanical load environments to develop silicon carbide (SiC) based integrated wireless sensor-transmitter suites for extreme temperature operation in nuclear… more
Abstract:ABSTRACT: The objective of this SBIR project is to develop a high temperature (225 degrees C +) energy harvesting solution for miniaturized smart wireless sensors that can be easily integrated with aircraft turbine engine components such as roller bearings and bearing assemblies to form a… more
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