Abstract:DESCRIPTION (provided by applicant): DiscoveryBioMed, Inc. (DBM) has launched an innovative and automation-friendly drug discovery program to screen synthetic organic small molecule collections on differentiated human adipocyte platforms to discover a newclass of therapeutic drugs for type 2… more
Abstract:DESCRIPTION (provided by applicant): An important discovery and validation event occurred recently within human cell-based drug discovery programs at DiscoveryBioMed, Inc. (DBM), yielding a lead class of cytostatic anti-proliferative small molecules thatdisplay nanomolar potency and marked efficacy… more
Abstract:Valepro proposes DOMINO as an intuitive cross-cultural solution for a common user defined operating picture (UDOP) for multi-mission situational awareness across US and Coalition forces by leveraging existing COTS capabilities used to analyze the global financial markets. The common analytical… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project is a feasibility assessment of using ultrathin magnetic iron oxide nanowires as positive contrast agent for magnetic resonance imaging (MRI). Each year, approximately 30 million MRI scans are performed for diagnostic or therapeutic… more
Abstract:PeopleTec, Inc., a Woman-Owned Small Business (WOSB), teamed with SECOTEC and ITT Exelis to provide an innovative and economical solution to Missile Defense Agency (MDA) requirements for evaluating high explosive detonation response to impact. Led by principle investigator Mr. Tim Cowles, the goal… more
Abstract:WCDMA payloads on fast-moving platforms, such as on satellites in Molniya orbits or on UAVs, will likely be added to the battlefield to assure the warfighter of reliable, ubiquitous communications. The algorithms for handoffs, timing, and Doppler correction suitable for near-Geosynchronous platforms… more
Abstract:WCDMA repeater payloads being developed for deployment on unmanned aerial vehicles will provide enhanced beyond line of sight coverage with guaranteed Quality of Service for the warfighter. To become a reality, these payloads will require deployable multiband base stations to serve as the ground… more
Abstract:Kappler proposes to further define and develop a novel fabric composite that when integrated into Personal Protective Equipment (PPE) garments,
provides protection to the wearer from multiple threats. The proposed research builds on the strength of the Phase I effort where Kappler validated
the base… more
Abstract:Proposed research will address the phenomenology and develop a technical concept of buried IED defeat through the creation of low-frequency electromagnetic fields in the ground by the LF current injection. The technical concept will be based on creating pulsed low-frequency currents in the ground… more
Abstract:Computer simulations of multi-phase flows are important for many applications. In the proposed work, we plan to advance Eulerian-Lagrangian methods by using Adaptive Mesh Refinement for multi-scale resolutions, and CPU-GPU parallelization to drastically reduce computing time. Eulerian-Lagrangian… more
Abstract:The goal of this SBIR project is to develop a computational tool for characterizing TM and GPS antennas mounted on plasma-engulfed hypersonic missiles and re-entry vehicles. The computational tool leverages coupled Computational Electro-Magnetics (CEM) and Computational Fluid Dynamics (CFD)… more
Abstract:Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is… more
Abstract:Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To… more
Abstract:ABSTRACT: Operating in a Service-Oriented Architecture (SOA) environment is risky because there is limited ability to gauge the quality of information, especially information that has been transformed multiple times as it flows within the SOA. To address this problem, CFDRC built METSI (Metadata… more
Abstract:The liberation of particles induced by rocket plume flow from spacecraft landing on unprepared regolith of the Moon, Mars, and other destinations poses high mission risks for robotic and human exploration activities. This process occurs in a combination of "extreme environments" that… more
Abstract:NASA space exploration missions require radiation-hardened memory technologies that can survive and operate over a wide temperature range. Memristors (memory-resistors) are a promising technology for the next generation of non-volatile memory (NVM) applications and offer a highly-desirable… more
Abstract:Launch vehicles experience extreme acoustic loads during liftoff driven by the interaction of rocket plumes and plume-generated acoustic waves with ground structures. Currently employed predictive capabilities to model the complex turbulent plume physics are too dissipative to accurately resolve the… more
Abstract:CFDRC proposes to develop a computational tool for transient, high-altitude events with mixed continuum and free molecular flow regimes. The proposed technology builds upon the Unified Flow Solver (UFS) previously developed by CFDRC, which will be leveraged with several new features for transient… more
Abstract:Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive… more
Abstract:In this STTR Phase I project, CFD Research Corporation and University of Nebraska at Omaha will develop a preliminary computationally-driven first-principles framework for discovery and design of non-RE-containing alloys for high temperature applications. While rare-earth (RE) based alloys have… more
Abstract:ABSTRACT: Unsteady aerodynamic loading and flow separation on modern high speed aircraft weapons bay doors can excite aircraft structural modes and lead to buffet, flutter, or fatigue-induced failures. Rigorous numerical simulations, wind tunnel and flight tests are typically carried out to… more
Abstract:ABSTRACT: Electromagnetic (EM) devices are used increasingly in society, with applications in communication, medicine, security, and defense, among others. To study safety and potential health hazards of EM devices, high-fidelity voxelized anatomical body models have been used in conjunction with… more
Abstract:ABSTRACT: Establishing adequate access controls that limit access to information without adversely denying access is critically needed by our warfighters in today"s complex battlefield environment. To address this need, CFDRC is proposing an innovative method called CAPSA (Controlling Access… more
Abstract:ABSTRACT: The objective of this program is to tailor and focus the capabilities of an existing software package for prediction of the rapid transient events following ignition of rocket-propelled munitions, as well as the firing of small caliber weapons. These events differ from missile plumes in… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.