Abstract:Distracted driving could have severe repercussions leading to loss of life, loss of property, and expensive lawsuits. While there can be many reasons for the driver to get distracted, research shows that the probability of accidents from texting/web-surfing while driving is an order of magnitude… more
Abstract:Congestion due to a work zone can cause accidents, as the drivers may not be prepared to take sudden actions ahead of a work zone or in some cases may not have enough visibility/time. Transmitting alert messages in advance can enable the driver to take safety precautionary measures so that it is… more
Abstract:Our approach for protecting critical program information in US weapons systems from exploitation or reverse-engineering efforts is based on a new sensor technology. Utilizing advances in the field of nanotechnology and the sub-field of plasmonics, our design is miniscule in size and allows for… more
Abstract:DESCRIPTION (provided by applicant): Dental implants have very high survival rates and are the fastest growing field in dentistry. But, high complication rates result in significant morbidit, cost, and disappointment. Better pre-operative knowledge of softtissue thickness and hard tissue contour… more
Abstract:SCIT Labs SBIR proposal is in response to the Department of Homeland Security (DHS) Office of Science and Technology call for new approaches to
cyber defense using Moving Target Defense (MTD). SCIT Labs' is proposing a set of research tasks to enable organizations to evaluate the viability of
Abstract:The goal of this research is to study the feasibility that mobile devices have the capabilities and accuracy to be used as positioning devices for connected vehicles programs. We will demonstrate this proposition by implementing positioning capturing apps using the build in GPS and accelerometers,… more
Abstract:High-current particle accelerators have need for low-impedance bellows connecting accelerating cells and in other areas of the accelerator. Typical techniques to decrease surface impedance are to use shields of superconducting Nb, however, as these shields move they produce particulates that can be… more
Abstract:Laser plasma accelerators have the potential to greatly reduce the cost and size of particle accelerators. A breakthrough in the gas profile used to accelerate the particles is required. Alameda Applied Sciences Corporation proposes to demonstrate a test bed system for tailoring the gas profile.… more
Abstract:Nb is the superconductor of choice for todays SRF accelerators, but the theoretical limits of the material are quickly being reached. An alternative material that could operate at higher temperatures and higher accelerating gradients would provide a reduction in cost for future SRF accelerators.… more
Abstract:Critical enriched isotopes are in short supply. Those that are available are purchased from unstable and foreign sources. Alameda Applied Sciences Corporation proposes to demonstrate a high throughput plasma enrichment technology for stable isotopes. Commercial Applications and Other Benefits:… more
Abstract:The World Health Organization estimates that more than one-third of the worldwide population is infected with Mycobacterium tuberculosis (MTB), the causative agent of most cases of tuberculosis (TB). Patients who are infected with MTB, but do not have active TB disease have latent tuberculosis… more
Abstract:ABSTRACT: ADI and ASU propose to develop a novel methodology for blade peak stress prediction from limited strain gage/tip-timing measurements when multiple vibratory modes are present. The current protocol assumes that only one mode is present and only provides upper and lower bound estimates of… more
Abstract:ABSTRACT: The extreme toxicity of organophosphate (OP) chemical warfare agents (CWA) is due to their specific, rapid, and irreversible reaction with cholinesterase enzymes. A significant portion of this reactive nature of OP agents is directly due to the unique metabolically active environment… more
Abstract:Dried blood spots (DBS) analysis has many advantages over standard liquid blood sample testing including: small sample size, ease of blood sampling, room temperature storage, minimal storage size requirement, and ease of shipping. Although these advantages are significant, there are still problems… more
Abstract:Agave BioSystems proposed to develop a system of Rapidly Adaptable Nanotherapeutics (RANT) by combining advanced bioformatics, with DNA-based nanoparticles, peptide nucleic acid (PNA) antisense oligonucleotides, and cell permeating peptides (CPPs). Advanced bioinformatics computing will allow for… more
Abstract:One major cause of the widespread of drug-resistant and virulent bacteria pathogen is the horizontal gene transfer of resistance and virulence genes in the form of plasmids. As proof-of concept for this Phase I effort, Agave BioSystems proposes to develop combinatorial therapeutics by inhibiting… more
Abstract:Wounds infected with drug-resistant Gram-negative bacteria can increase morbidity, hospital length of stay and cost. Among these Klebsiella pneumoniae and Pseudomonas aeruginosa have become important causes of concern in military personnel wounded in battlefield. New classes of antimicrobial agents… more
Abstract:With no clinically approved antiviral therapy available for treatment of flavivirus infections, the development of efficient vaccines and antiviral agents for prevention and treatment of infections is an urgent health priority. A combination of structure-based in silico models, in vitro and… more
Abstract:Bacterial enteric pathogens causing travelers"diarrhea (TD) in developing countries include enterotoxigenic E. coli (50%), Camplyobacter jejuni, Shigella sonnei and Shigella flexneri, while Norovirus is a common viral cause. High risk regions for TD include areas where US service members are… more
Abstract:Field testing of water samples is needed for broad and sensitive detection of toxic industrial chemicals, or TICs. The use of unicellular organisms in cell-based detection systems is particularly advantageous both because these organisms have developed a natural ability to respond to environmental… more
Abstract:The long-term goal for this effort is to develop a low-cost, high-temperature thruster. Within the attitude control propulsion community, many efforts have focused on development of ultra-high temperature precious metal alloys and systems that give long life and good performance (e.g., Ir/Re). … more
Abstract:ABSTRACT: In the proposed effort, ASI will demonstrate the feasibility of a practical, proven method for significantly increasing the heat transfer coefficient inside regenerative cooling channels. The technique, used in the electronics industry for high heat flux removal applications, requires… more
Abstract:The research objective of the proposed work is to apply the foundational knowledge of ultrasonic bonding, metallic composites, microstructure transformation kinetics and material failure criteria to create a multi-scale simulation model for the optimization of ultrasonic additive manufacturing (UAM)… more
Abstract:ABSTRACT: Applied Optimization, Inc. (AO) has developed computational process simulation for the prediction of temperature, residual stress, and melt pool control during the material feed DDM processes (e.g. LENSTM and EBFFF). The Phase I work plan is to extend this existing simulation technology… more
Abstract:ABSTRACT: Applied Optimization, Inc. proposes to develop a prototype hardware and software system for concurrent collection of metric observations and single-point spectral brightness data. The concurrency will be attained by using all but a few percent of the CCD pixel array for metric… more
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