Abstract:This effort develops automatic detection of malicious binary code based on syntax-independent logical control flow patterns. Control flow patterns yield specific detectable signatures that can be extracted from binary code. Because they are based on functional control flow, these signatures also… more
Abstract:This effort will develop a capability for automated modification of binary code based on canonical algorithm patterns of control flows. Since these methods are based on control flow, they are OS and language independent. The methods offer a path towards building operating systems that are… more
Abstract:Scrub typhus, caused by Orientia tsutsugamushi poses a threat to U.S. forces deployed to the Asian/Australian/Pacific regions during contingency and peacekeeping operations. Development of an assay for the detection of O. tsutsugamushi that is rapid, accurate, field-usable and soldier-friendly is… more
Abstract:The first objective of Phase II is to validate the ready-to-use DNA-based dengue diagnostics kit under laboratory conditions using culture-derived dengue viruses as well as clinically confirmed dengue infected samples from different geographic origins. These prototype products will be developed for… more
Abstract:Filament wound fiber reinforced composite rocket motor cases are widely used on MDA missile systems. However, significant performance and behavior characteristics of the composite structure can be affected by degradation resulting from exposure to environmental conditions or damage resulting from… more
Abstract:Acellent Technologies proposes to develop an innovative one-of-a-kind sensor cluster based structural health monitoring system that combines Acellent's current single-element SMART Layer actuator/sensor network together with multi-element phased arrays to produce a Sensor Cluster Network. The… more
Abstract:The performance and behavior characteristics of nearly all in-service structures can be affected by degradation resulting from sustained use as well as from exposure to severe environmental conditions. Condition awareness of structures in (near) real-time is therefore an important factor that can… more
Abstract:The objective of this proposed project is to develop dual E/M impedance and wave propagation based innovative structural health monitoring (SHM) system for application to composite structures for Army rotorcraft and unmanned air vehicle platforms. Composites can incur invisible damage from impacts,… more
Abstract:Acellent technologies, Inc. proposes to develop a dual E/M impedance and wave propagation based innovative structural health monitoring (SHM) system for application to composite structures for Army rotorcraft and unmanned air vehicle platforms. Composites can incur invisible damage from impacts,… more
Abstract:In recent years, Structural Health Monitoring (SHM) is increasingly being evaluated by the industry as a possible method to improve the safety and reliability of structures and thereby reduce their operational cost. However, the scalability and applicability of SHM systems for the monitoring of… more
Abstract:The Future Combat System (FCS) military diesel engine propulsion systems tribological considerations are predicted to be compromised primarily by the temperature capability of the lubricating fluid. Thermal oxidation resulting in lubricant work in rigid condition breakdown and formation of deposits… more
Abstract:Mastitis, an infection of the milk-producing glands of dairy cows, is a $5 billion problem worldwide. The current, on-site method used to diagnose mastitis, and to monitor its incidence, is to count the total number of "body cells" (white cells and other body cells) present in the milk. There has… more
Abstract:75824-Induction cores, used to accelerate the heavy ion beams in inertial fusion, are built around the outer diameter of the cryostat that houses the superconducting quadrupole array. A compact cryostat would be highly desirable for reducing the cost of the induction cores. Recent experience with… more
Abstract:75879-Hydrogen storage materials with a large capacity are needed to store, transport, and utilize hydrogen for fuel cells. This project will employ a unique combinatorial technique for rapidly screening a number of nanocrystalline alloys and intermetallics, in order to identify prospective… more
Abstract:M19 grade silicon steel is the most commonly used soft magnet for a number of applications such as in the manufature of motors. Advanced Materials Corporation proposes to fabricate new, proprietary magnet compositions and bonded magnets employing novel processing techniques. The saturation induction… more
Abstract:This SBIR Phase II project is to continuously and fully develop the title parallel computational design tools initiated in Phase I into superpowerful, commercializable prototype design tools (computer codes) in the following manner: (i) adopting/extending our own superefficient Integral… more
Abstract:DESCRIPTION (provided by applicant): A laser-based acoustic emission (AE) detection device is proposed (Phase I and II) for work site structural stability assessment in order to reduce the occupational injuries and fatalities caused by roof falls, sidewall
crumples, stop collapses, slope slides,… more
Abstract:The objective of this project is to develop and validate an improved technology base for the cold-working of high strength aluminum alloys. The improved technology base consists of the following three legs: 1. A test-validated CAD/CAM tool for performing virtual cold-working and for virtual… more
Abstract:DESCRIPTION (provided by applicant): Fluorescent semiconductor nanocrystals or quantum dots have many properties that make them superior to traditional dyes as fluorescent markers. Quantum dots have higher extinction coefficients making them brighter than traditional dyes (up to 1000 times brighter… more
Abstract:In this Phase I, Agave BioSystems proposes a novel approach for the development of a rapid and sensitive detection system for arsenic in drinking water based on the bioluminescent protein aequorin. The simplicity and ruggedness of this technology has the potential for providing low cost, on-line,… more
Abstract:Current technologies for marking of landing zones as well as areas for search and rescue have significant drawbacks ranging from the additional weight of batteries for some systems to plastic and metallic debris left behind. There are clear advantages both operationally and environmentally to… more
Abstract:Because many chemical and biological toxins selectively target respiratory endothelial cells, a biosensor using these cells in combination with Electric Cell-substrate Impedance Sensing (ECIS) technology has many useful applications for detection and early warning monitoring of a broad range of… more
Abstract:Due to the extensive amounts of data generated from the genome sequencing projects, the focus of genomics has shifted from elucidating DNA sequence to the interpretation of gene function. In addition, as proteins are most often the targets of drugs, a method of studying the genome at the protein… more
Abstract:Because endothelial cells organize to form a tight barrier under normal conditions, several electrical devices have been used to measure the electrical resistance of endothelial cell monolayers. An Electric Cell-substrate Impedance Sensing (ECIS) system can measure the electrical impedance of… more
Abstract:DESCRIPTION (provided by applicant):
In response to the solicitation for development of nanotechnologies to improve cancer diagnosis by NCI, Agave BioSystems, in collaboration with Dr. George Malliaras, of the Department of Materials Science and Engineering at Cornell University, proposes to… more
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