Abstract:This proposal will provide immediate decision support data, enabling appropriate and cost effective responses (shut down vs. continue) for training exercises/facilities. Specifically, the DoD requires the ability to "train as we fight and fight as we train", however training is severely limited by… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer (STTR) Phase I project will develop a new class of multifunctional nanoparticle assemblies for optical disease diagnosis and treatment. The nanoparticle… more
Abstract:Aegisounds existing Digital Active Noise Reduction (DANR) HPD product configuration, developed under a prior Lockheed Martin JSF SDD program, represents the baseline hearing protector system for this SBIR project. Affordability and performance requirements formed the basis for a Phase I… more
Abstract:DESCRIPTION (provided by applicant): This project aims to develop talactoferrin (TLF, recombinant human lactoferrin) as a therapeutic agent to treat prematurely born neonates. The treatment will be given orally shortly after birth to prevent nosocomial inf
ections (NIs) due to abnormal bacterial… more
Abstract:The crude oil will be depleted within 40 years, alternative fuels have to be developed to drive our transportation systems, and biodiesel appears to be the most promising fuel of the future. Biodiesel is renewable, non-toxic, and biodegradable, it can be used in existing diesel engines without… more
Abstract:This Small Business Innovation Research Phase I research project will use femtosecond laser machining to fabricate Lithium ion based nanobatteries composed of arrays of nanocells. In addition, an array of addressable batteries will also be constructed. A femtosecond laser is a powerful tool to… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase I project will involve the development of a noninvasive intracranial pressure (ICP) monitor based on a pilot clinical study correlating ocular blood… more
Abstract:This proposal covers the development of audio processing technology that enables improved communications capability among first responders. The goal is to improve the SNR of the audio signal that is input to the radio or other communication system when the user is in a noisy environment. The… more
Abstract:This proposal describes a specific problem within the Intelligence community. Because of a lack of GEOINT tools for capturing storing and delivering expert knowledge from experienced analysts, new analysts have difficulty in quickly gaining the level of skill that those expert analysts possess.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project explores a novel detection system for DNA microarrays, which are coin-size glass chips containing diverse molecules of genetic material. DNA microarrays have revolutionized basic research and industrial drug discovery, but have… more
Abstract:DESCRIPTION (provided by applicant): The CardioMetrix Endoluminal HF Monitoring System is intended to provide patients with ambulatory monitoring their heart function, allowing for better management of their disease and allowing them to live a life less en
cumbered by HF. The system uses ultrasound… more
Abstract:DESCRIPTION (provided by applicant): The business of developing, testing, and approving new medical treatments for use in the U.S. has changed dramatically over the past 10 years. In recent years we have observed declining approvals, increasing costs, incr
easing regulatory process complexity,… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will demonstrate the feasibility of growing high-quality fibers of periodically poled Mg-doped LiNbO3 for visible light generation, by a modified version of the laser heated pedestal growth (LHPG) method. Other methods used to grow these… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project develops a diagnostic platform for herpes viruses by combining gold nanoparticle labels, high-speed fluid handling, and sandwich-based heterogeneous immunoassays with advances in surface enhanced Raman scattering (SERS). Herpes has… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase I project addresses the need for a low cost technique to significantly minimize the time required to complete a diagnostic test while maintaining and… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer (STTR) Phase I project is to synthesize an intelligent polymer hydrogel, and to develop a wireless, remote and sensitive magnetoelastic sensor for rapid… more
Abstract:DESCRIPTION (provided by applicant): Rapid, simple and reliable detection of staphylococcal enterotoxin B (SEB) in food products is a crucial step to ensure food safety and prevent food intoxication and gastrointestinal diseases. Current SEB detection is e
nzyme-linked immunosorbent assay (ELISA),… more
Abstract:DESCRIPTION (provided by applicant): Logistic regression is the most frequently used model for binary data and has widespread applicability in the health, behavioral, and physical sciences. Over two thousand research papers were published in 1999 in which
logistic regression was in the title of… more
Abstract:DESCRIPTION (provided by applicant): Longitudinal data are very common in sociological, behavioral and biomedical researches. The data may come from longitudinal clinical trials, community surveys, family studies or spatial-temporal studies to investigate
some health outcomes. The responses are… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes the improvement of real-time PCR, a DNA-based rapid-detection method, for detection of food-borne pathogens such as Salmonella. Current methods are inadequate to accurately detect pathogens in foods such as chocolate,… more
Abstract:Modern multi-core and many-core digital signal processors (mDSPs) offer greater processing capabilities than any other reprogrammable device, with some even performing on par with an FPGA. mDSP development environments support standard languages such as C/C++, and provide application scheduling… more
Abstract:The International Linear Collider (ILC) will need hundreds of modulators to power the 10-MW, long pulse (1.4 ms) klystrons. A Marx modulator controlled by solid-state switches promises higher efficiency, longer lifetime, and reduced cost compared to existing hard tube modulator options. However,… more
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