Abstract:This proposal will provide immediate decision support data, enabling appropriate and cost effective responses (shut down vs. continue) for training exercises/facilities. Specifically, the DoD requires the ability to "train as we fight and fight as we train", however training is severely limited by… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer (STTR) Phase I project will develop a new class of multifunctional nanoparticle assemblies for optical disease diagnosis and treatment. The nanoparticle… more
Abstract:Aegisounds existing Digital Active Noise Reduction (DANR) HPD product configuration, developed under a prior Lockheed Martin JSF SDD program, represents the baseline hearing protector system for this SBIR project. Affordability and performance requirements formed the basis for a Phase I… more
Abstract:Agve BioSystems in collaboration with Carl A. Batt propose to develop decon-nanoparticles which will leverage ongoing opportunities in enzyme engineering and the fabrication of functionalized magnetic nanoparticles. Enhanced performance will be engineered into the system to improve the catalytic… more
Abstract:Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and… more
Abstract:During the normal course of research, development, and testing by the DOD small quantities of environmentally hazardous waste propellants, explosives, and pyrotechnics (PEP) are produced. The compliance costs and burden associated with open burn/open detonation operations are considerable, including… more
Abstract:Improving age-related decrease in cognitive and physical capabilities has tremendous potential for the civilian population and military personnel, including prolonged aptitude of highly-trained military personnel and lowering of healthcare costs. Mitocho
Abstract:Q fever is caused by the bacterium Coxiella burnetii and presents with acute symptoms indistinguishable from many other blood infections. Chronic infection, however, can result in endocarditis, with a high mortality rate (up to 60% of chronic Q fever cases) and requiring open-heart surgery to… more
Abstract:Development of an effective malarial vaccine has been slow, although recent success in vaccine development has been achieved by using the Plasmodium falciparum circumsporozoite surface protein (CSP)-hepatitis B surface antigen fusions, in conjunction with hepatitis B particles (the RTS, S… more
Abstract:The rapid evaluation of drinking water toxicity in the field is a necessity for the safety of our soldiers. To achieve field portability and sensitive screening for identification of toxic industrial chemicals (TICs) a handheld device that is biologically-based and easy to use with components that… more
Abstract:Rapid detection of the total trihalomethanes (TTHM) in treated drinking water is essential for compliance with the Environmental Protection Agency's (EPA) Stage 2 Disinfectants and Disinfection Byproducts (DBP) Rule, which limits the maximum contaminant level of TTHM in drinking water. The current… more
Abstract:DESCRIPTION (provided by applicant): This project aims to develop talactoferrin (TLF, recombinant human lactoferrin) as a therapeutic agent to treat prematurely born neonates. The treatment will be given orally shortly after birth to prevent nosocomial inf
ections (NIs) due to abnormal bacterial… more
Abstract:The crude oil will be depleted within 40 years, alternative fuels have to be developed to drive our transportation systems, and biodiesel appears to be the most promising fuel of the future. Biodiesel is renewable, non-toxic, and biodegradable, it can be used in existing diesel engines without… more
Abstract:This Small Business Innovation Research Phase I research project will use femtosecond laser machining to fabricate Lithium ion based nanobatteries composed of arrays of nanocells. In addition, an array of addressable batteries will also be constructed. A femtosecond laser is a powerful tool to… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research Phase I project will involve the development of a noninvasive intracranial pressure (ICP) monitor based on a pilot clinical study correlating ocular blood… more
Abstract:The Phase I objective is a conceptual design of a hyperspectral/multimodal fundus camera for assessing laser damage. The premise to be ultimately proven in this project is that damage to the fundus, from laser irradiation, may be characterized and detected by reflectance spectra, and by measuring… more
Abstract:This proposal covers the development of audio processing technology that enables improved communications capability among first responders. The goal is to improve the SNR of the audio signal that is input to the radio or other communication system when the user is in a noisy environment. The… more
Abstract:This proposal describes a specific problem within the Intelligence community. Because of a lack of GEOINT tools for capturing storing and delivering expert knowledge from experienced analysts, new analysts have difficulty in quickly gaining the level of skill that those expert analysts possess.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project explores a novel detection system for DNA microarrays, which are coin-size glass chips containing diverse molecules of genetic material. DNA microarrays have revolutionized basic research and industrial drug discovery, but have… more
Abstract:DESCRIPTION (provided by applicant): The CardioMetrix Endoluminal HF Monitoring System is intended to provide patients with ambulatory monitoring their heart function, allowing for better management of their disease and allowing them to live a life less en
cumbered by HF. The system uses ultrasound… more
Abstract:DESCRIPTION (provided by applicant): The business of developing, testing, and approving new medical treatments for use in the U.S. has changed dramatically over the past 10 years. In recent years we have observed declining approvals, increasing costs, incr
easing regulatory process complexity,… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will demonstrate the feasibility of growing high-quality fibers of periodically poled Mg-doped LiNbO3 for visible light generation, by a modified version of the laser heated pedestal growth (LHPG) method. Other methods used to grow these… more
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