Abstract:DESCRIPTION (provided by applicant): Since the earliest examination of cellular structures, biologists have been fascinated by observing cells using light microscopy. The advent of fluorescent labeling technologies plus the plethora of sophisticated light
microscope techniques now available make… more
Abstract:The project addresses the needs of students and adults with intellectual disabilities forwritten self-expression by designing, developing, and testing a universally designed, multimediacompositioning software application. This application creates a specific format for independent expressionof… more
Abstract:Very little research and development has been done to address the unique assistive technology needs of individuals with traumatic brain injuries. In response to the immediate need for executive functioning supports for soldiers with TBI/PTST, an all-in-one (Ai1) system is proposed to provide… more
Abstract:This project develops a location-based method for improving access to information in thecommunity (i.e.: public places such as parks, zoos, bus station and stops, information kiosks, touristattractions, and other places of public accommodation) that is not solely in text format. This… more
Abstract:This project addresses the critical need for money management skills training necessary forindependent community living through the development of a software system (Money Coach). MoneyCoach utilizes both hand-held technology and desktop software to assist individuals with intellectualdisabilities… more
Abstract:This project develops and evaluates a multimedia instant messaging (IM) system, VisualMessenger, that is designed to be usable independently by individuals with intellectual and othercognitive disabilities. The prototype software system developed in this project is used in a betweensubjectspilot… more
Abstract:This project evaluates the technical merit and feasibility of Pocket Email, a PDA-basedaccessible email program which is universally designed to meet the unique needs of individuals withintellectual disabilities for communicating via email with family members and other caregivers while incommunity… more
Abstract:DESCRIPTION (provided by applicant): WAYFINDER: A Cognitive Aid for Independent Transportation ABSTRACT Transportation and mobility have long been areas of great dependency for individuals with intellectual disabilities, such as mental retardation. Few ind
ividuals with intellectual disabilities… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will demonstrate the feasibility of a platform technology for cancer therapy which overcomes the inherent shortcomings of other attempts to delivery siRNA to cancer cells. The difficulty with current siRNA delivery is that the enzymes in… more
Abstract:Our proposed receiver design will satisfy or exceed the requirements set forth in this solicitation. The key innovation is our melding of approaches - to produce a compact lightweight receiver with onboard processing that leverages picosecond timing resolution and burst acquisition methodology… more
Abstract:Advanced Technologies Group, Inc. (ATG) proposes to develop an innovative High Powered Ram-Air-Turbine (HiRAT) capable of producing over 60kw of power at an air speed of 250 knots. During Phase I ATG will design, analyze and test a scaled turbine to determine feasibility. Preliminary analysis… more
Abstract:This SBIR development effort concentrates on blade tip clearance management in the high pressure turbine. Improved seals in this location of a gas-turbine engine provide the highest benefits to overall engine efficiency, service life, stability and stall margin. The COAS proposed will deliver a… more
Abstract:This proposal will provide immediate decision support data, enabling appropriate and cost effective responses (shut down vs. continue) for training exercises/facilities. Specifically, the DoD requires the ability to "train as we fight and fight as we train", however training is severely limited by… more
Abstract:The development of affordable, high performance hearing protection and communication systems is critical for USAF and DOD aircraft maintainers who must work in the vicinity of jet exhaust noise during launch and recovery operations. Aegisound is in a unique position to leverage recently completed… more
Abstract:Semivolatile organic matter is pervasive in the atmosphere. Its effect on the radiation balance of the earth depends on how this material is partitioned between the vapor and particle phases. Yet, no currently available instrumentation provides simultaneous, quantitative measurement of… more
Abstract:Rapid detection of the total trihalomethanes (TTHM) in treated drinking water is essential for compliance with the Environmental Protection Agency's (EPA) Stage 2 Disinfectants and Disinfection Byproducts (DBP) Rule, which limits the maximum contaminant level of TTHM in drinking water to 80 parts… more
Abstract:DESCRIPTION (provided by investigator): Lyme disease, caused by the gram-negative spirochete Borrelia burgdorferi and transmitted by Ixodid tick species, is the leading vector-borne infectious disease in the United States, with a steady rise in the number
of cases reported each year. The most… more
Abstract:The key to effective management of malaria is accurate diagnosis that is also rapid. The "gold standard" microscopy is time-consuming and labor-intensive and suffers from retirement of microscopic diagnostic experts and inaccurate slide reading. A field-deployable diagnostic method that is… more
Abstract:Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can… more
Abstract:Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and… more
Abstract:DESCRIPTION (provided by applicant): This project aims to develop talactoferrin (TLF, recombinant human lactoferrin) as a therapeutic agent to treat prematurely born neonates. The treatment will be given orally shortly after birth to prevent nosocomial inf
ections (NIs) due to abnormal bacterial… more
Abstract:DESCRIPTION (provided by applicant): Severe sepsis is a major cause of morbidity and mortality throughout the world. It is the leading cause of death in non-coronary intensive care units (ICUs) in the United States, with more than 750,000 cases occurring e
very year. This means that in the United… more
Abstract:An innovative concept for a scalable beamformer that can be applied to the full range of Air Force radars is proposed. The concept is photonics based and currently supports transmit/receive applications over the 0.1 to 20 GHz band. The design provides a digitally controlled True Time Delay… more
Abstract:In this program, Agiltron and the group of Professor D. W. Wang at Boston College propose a novel nano-porous coating for next generation MDA IR anti-reflection (AR) coatings for detectors and optics. The collaborative research leverages recent progress in nano-material development at Boston College… more
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