Abstract:DESCRIPTION (provided by applicant): The purpose of this research is to determine the efficacy of orally administered recombinant human lactoferrin (rhLF) in Phase II clinical trials in patients with mild to moderate asthma.
Asthma is one of the most prevalent chronic inflammatory diseases in the… more
Abstract:DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a long-term, debilitating disorder that causes loss of memory and cognitive functions. There is an urgent need for effective therapeutic agents to ameliorate the symptoms of AD. Important molecular drug targets in AD are the… more
Abstract:This Small Business Innovation Research (SBIR) Phase II research project develops the concept of using hand-held, mobile devices to link the physical world to information networks using advanced pattern and symbol recognition technology that will be deployed on the mobile device. The proposed mobile… more
Abstract:DESCRIPTION (provided by applicant): The population of aging adults in the United States is entering a period of rapid growth as baby boomers get older and life expectancy continues to increase. One problem that is significantly affecting their ability to live and function independently is low… more
Abstract:DESCRIPTION (provided by applicant): To address wayfinding difficulties and physical activity among cognitively-impaired older adults, we propose to develop a navigation aid that can be attached to three- and four-wheeled rollators. The navigation aid will provide navigation assistance to the user… more
Abstract:The Universal Trail Assessment Process (UTAP) and TrailWare, software for UTAP data, were developed to obtain objective trail information. Over 700 people within Federal, State, local and non-profit agencies have been UTAP trained throughout the US. Requiring 9 to 15 person hours per mile of trail… more
Abstract:DESCRIPTION (provided by applicant): There, is a high incidence of overuse injuries among manual wheelchair users. One method to prevent the development or delay the onset of injuries is to reduce the physical demand on the user during wheelchair propulsion. Configuration of the wheelchair can have… more
Abstract:DESCRIPTION (provided by applicant): People with disabilities have increased health risks as a result of a sedentary lifestyle. Limited access to fitness equipment is a primary barrier to physical activity and a significant environmental barrier to the health and well-being of people with… more
Abstract:People with mobility impairments are excluded from trails, shared-use paths, parks and other public areas where barriers are erected to prevent access by motorized trail vehicles (MTVs). To ensure the safety of trail users and the integrity of the natural environment, many recreation and/or… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project presents a new, non-contact method for sorting particles by size. The primary objective of Phase I activities is to evaluate the technical and commercial feasibility of a particle sorter based upon Aerodynamic Vectoring. This objective… more
Abstract:Chameleon Optics was founded on March 10, 1998 in Philadelphia, PA, for the purpose of developing unique devices based on proprietary chromogenic (color-changing) coatings. The company is a resident organization of the University City Science Center, one of the largest and most successful business… more
Abstract:Phase I work was targeted at investigation of a meteorological sensing package for unmanned aerial vehicles (UAVs). Much of this work was based upon operational experience gained during Cloud Cap Technology's involvement with numerous meteorological experiments which involved the use of small UAVs.… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase II SBIR proposal for a major extension to Cytel's flagship software, StatXact, to perform small sample exact inference for correlated categorical data. Such data are common in biomedical research, especially in areas such as genetics,… more
Abstract:DESCRIPTION (provided by applicant): The success and sensitivity of DNA detection is limited in important clinical, forensic, and environmental applications due to the presence of complex biological samples, such as blood, which reduce amplification efficiency. Different pre-PCR treatments that are… more
Abstract:ErisTech, a minority owned small certified defense contracting business based in San Diego, proposes a solution that will explore "best of breed" energy collection and storage techniques for surveillance airships in the stratosphere. Phase I work will consist of developing the most efficient power… more
Abstract:Successful completion of marketing and logistics research will provide post and pole plants in rural communities, forestland managers, and distribution businesses with critical understanding of the urban retail and wholesale marketplace and how best to position roundwood as a building, woodcraft and… more
Abstract:The project addresses National priorities to concurrently reduce fuel loadings (i.e., remove excess forest biomass) from forested lands and improve the economic and employment sustainability of rural communities. Forestlands adjacent to roads and in the true wildland-urban interface (WUI) are among… more
Abstract:DESCRIPTION (provided by applicant): Ischemic stroke is a major source of illness and burden in the U.S. Stroke survivors are at high risk for recurrence, and therefore they are an important group for secondary prevention. However, there are three major gaps of knowledge in stroke survivors that are… more
Abstract:DESCRIPTION (provided by applicant): In the United States, the right to determine if medical tests, procedures or treatments are to be conducted is manifest through the process of informed consent. The doctrine of informed consent specifies that competent individuals have the right to make a "right"… more
Abstract:Due to the widespread use of landmines in past and current conflicts, effective mine-clearing systems are in ever-increasing demand in today's military and humanitarian efforts around the world. GS Engineering (GSE) has invented a unique system that will greatly advance the current state of the art… more
Abstract:The operational capabilities of the Marine Corps Expeditionary Fighting Vehicle (EFV) are a leap-ahead technology as compared to the old AAV/P7. The early vehicle prototypes have identified several areas of improvement to make this an outstanding vehicle. This proposal will be directed at reducing… more
Abstract:Bushing degradation in tracked vehicles has attracted attention in the recent conflicts in hot, arid environments around the globe. Due to the increased ambient temperatures and the need for speed and agility, bushings are experiencing higher forces and higher temperatures. Due to this combined… more
Abstract:The current fuel economy of military vehicles limits the effectiveness of the deployment into various theaters. As Future Combat Systems (FCS) vehicles are developed, fuel economy, overall weight, performance, power generation, survivability, emissions and maintenance will highlight the need for… more
Abstract:79633 Although high-resolution geophysical measurements have been proven to be valuable for characterizing the subsurface at contaminated DOE sites, the data are not yet in routine use. The obstacles are twofold: (1) the potential inconsistency between intepretations of geophysical data and… more
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